B cell rich meningeal inflammation associates with increased spinal cord pathology in multiple sclerosis
Reali, Camilla, Magliozzi, Roberta, Roncaroli, Federico, Nicholas, Richard, Howell, Owain W., Reynolds, Richard
Published in Brain pathology (Zurich, Switzerland) (01.07.2020)
Published in Brain pathology (Zurich, Switzerland) (01.07.2020)
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A Gradient of neuronal loss and meningeal inflammation in multiple sclerosis
Magliozzi, Roberta, Howell, Owain W., Reeves, Cheryl, Roncaroli, Federico, Nicholas, Richard, Serafini, Barbara, Aloisi, Francesca, Reynolds, Richard
Published in Annals of neurology (01.10.2010)
Published in Annals of neurology (01.10.2010)
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Inflammatory intrathecal profiles and cortical damage in multiple sclerosis
Magliozzi, Roberta, Howell, Owain W., Nicholas, Richard, Cruciani, Carolina, Castellaro, Marco, Romualdi, Chiara, Rossi, Stefania, Pitteri, Marco, Benedetti, Maria Donata, Gajofatto, Alberto, Pizzini, Francesca B., Montemezzi, Stefania, Rasia, Sarah, Capra, Ruggero, Bertoldo, Alessandra, Facchiano, Francesco, Monaco, Salvatore, Reynolds, Richard, Calabrese, Massimiliano
Published in Annals of neurology (01.04.2018)
Published in Annals of neurology (01.04.2018)
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Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier
Gallego-Delgado, Patricia, James, Rachel, Browne, Eleanor, Meng, Joanna, Umashankar, Swetha, Tan, Li, Picon, Carmen, Mazarakis, Nicholas D, Faisal, A Aldo, Howell, Owain W, Reynolds, Richard
Published in PLoS biology (01.12.2020)
Published in PLoS biology (01.12.2020)
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Meningeal inflammation is widespread and linked to cortical pathology in multiple sclerosis
Howell, Owain W., Reeves, Cheryl A., Nicholas, Richard, Carassiti, Daniele, Radotra, Bishan, Gentleman, Steve M., Serafini, Barbara, Aloisi, Francesca, Roncaroli, Federico, Magliozzi, Roberta, Reynolds, Richard
Published in Brain (London, England : 1878) (01.09.2011)
Published in Brain (London, England : 1878) (01.09.2011)
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Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats
GARDNER, Christopher, MAGLIOZZI, Roberta, DURRENBERGER, Pascal F, HOWELL, Owain W, RUNDLE, Jon, REYNOLDS, Richard
Published in Brain (London, England : 1878) (01.12.2013)
Published in Brain (London, England : 1878) (01.12.2013)
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Meningeal inflammation plays a role in the pathology of primary progressive multiple sclerosis
CHOI, Sung R, HOWELL, Owain W, CARASSITI, Daniele, MAGLIOZZI, Roberta, GVERIC, Djordje, MURARO, Paolo A, NICHOLAS, Richard, RONCAROLI, Federico, REYNOLDS, Richard
Published in Brain (London, England : 1878) (01.10.2012)
Published in Brain (London, England : 1878) (01.10.2012)
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Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism
Yutuc, Eylan, Angelini, Roberto, Baumert, Mark, Mast, Natalia, Pikuleva, Irina, Newton, Jillian, Clench, Malcolm R., Skibinski, David O. F., Howell, Owain W., Wang, Yuqin, Griffiths, William J.
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2020)
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Journal Article
Meningeal inflammation and cortical demyelination in acute multiple sclerosis
Bevan, Ryan J., Evans, Rhian, Griffiths, Lauren, Watkins, Lewis M., Rees, Mark I., Magliozzi, Roberta, Allen, Ingrid, McDonnell, Gavin, Kee, Rachel, Naughton, Michelle, Fitzgerald, Denise C., Reynolds, Richard, Neal, James W., Howell, Owain W.
Published in Annals of neurology (01.12.2018)
Published in Annals of neurology (01.12.2018)
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Journal Article
“Ependymal‐in” Gradient of Thalamic Damage in Progressive Multiple Sclerosis
Magliozzi, Roberta, Fadda, Giulia, Brown, Robert A., Bar‐Or, Amit, Howell, Owain W., Hametner, Simon, Marastoni, Damiano, Poli, Alberto, Nicholas, Richard, Calabrese, Massimiliano, Monaco, Salvatore, Reynolds, Richard
Published in Annals of neurology (01.10.2022)
Published in Annals of neurology (01.10.2022)
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The neuropathological basis of clinical progression in multiple sclerosis
Reynolds, Richard, Roncaroli, Federico, Nicholas, Richard, Radotra, Bishan, Gveric, Djordje, Howell, Owain
Published in Acta neuropathologica (01.08.2011)
Published in Acta neuropathologica (01.08.2011)
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Multiple sclerosis compartmentalised inflammation profiles in a Northern Ireland pre-DMT, post-mortem tissue cohort
Rachael, Kee, Michelle, Naughton, Samuel, Ward, McDonnell Gavin, V, Howell Owain, W, Fitzgerald Denise, C
Published in Journal of neurology, neurosurgery and psychiatry (28.11.2023)
Published in Journal of neurology, neurosurgery and psychiatry (28.11.2023)
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Complement activation and increased anaphylatoxin receptor expression are associated with cortical grey matter lesions and the compartmentalised inflammatory response of multiple sclerosis
Evans, Rhian, Watkins, Lewis M, Hawkins, Kristen, Santiago, Gabriella, Demetriou, Constantinos, Naughton, Michelle, Dittmer, Marie, Rees, Mark I, Fitzgerald, Denise, Morgan, B Paul, Neal, James W, Howell, Owain W
Published in Frontiers in cellular neuroscience (22.03.2023)
Published in Frontiers in cellular neuroscience (22.03.2023)
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Visualizing Cholesterol in the Brain by On-Tissue Derivatization and Quantitative Mass Spectrometry Imaging
Angelini, Roberto, Yutuc, Eylan, Wyatt, Mark F, Newton, Jillian, Yusuf, Fowzi A, Griffiths, Lauren, Cooze, Benjamin J, El Assad, Dana, Frache, Gilles, Rao, Wei, Allen, Luke B, Korade, Zeljka, Nguyen, Thu T. A, Rathnayake, Rathnayake A. C, Cologna, Stephanie M, Howell, Owain W, Clench, Malcolm R, Wang, Yuqin, Griffiths, William J
Published in Analytical chemistry (Washington) (23.03.2021)
Published in Analytical chemistry (Washington) (23.03.2021)
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Comparing the Pathology, Clinical, and Demographic Characteristics of Younger and Older‐Onset Multiple Sclerosis
Knowles, Sarah, Middleton, Rod, Cooze, Benjamin, Farkas, Ildiko, Leung, Yeung Yeung, Allen, Kelsey, Winslade, Molly, Owen, David R.J., Magliozzi, Roberta, Reynolds, Richard, Neal, James W., Pearson, Owen, Nicholas, Richard, Pickrell, W. Owen, Howell, Owain W.
Published in Annals of neurology (01.03.2024)
Published in Annals of neurology (01.03.2024)
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HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage
Dietz, Karen, He, Ye, Reynolds, Richard, Casaccia, Patrizia, Shen, Siming, Kim, Jin Young, Howell, Owain
Published in Nature neuroscience (01.02.2010)
Published in Nature neuroscience (01.02.2010)
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Detection of Epstein–Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look
Aloisi, Francesca, Serafini, Barbara, Magliozzi, Roberta, Howell, Owain W., Reynolds, Richard
Published in Brain (London, England : 1878) (01.12.2010)
Published in Brain (London, England : 1878) (01.12.2010)
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The association between neurodegeneration and local complement activation in the thalamus to progressive multiple sclerosis outcome
Cooze, Benjamin J., Dickerson, Matthew, Loganathan, Rukshikah, Watkins, Lewis M., Grounds, Ethan, Pearson, Ben R., Bevan, Ryan Jack, Morgan, B. Paul, Magliozzi, Roberta, Reynolds, Richard, Neal, James W., Howell, Owain W.
Published in Brain pathology (Zurich, Switzerland) (01.09.2022)
Published in Brain pathology (Zurich, Switzerland) (01.09.2022)
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Complement is activated in progressive multiple sclerosis cortical grey matter lesions
Watkins, Lewis M, Neal, James W, Loveless, Sam, Michailidou, Iliana, Ramaglia, Valeria, Rees, Mark I, Reynolds, Richard, Robertson, Neil P, Morgan, B Paul, Howell, Owain W
Published in Journal of neuroinflammation (22.06.2016)
Published in Journal of neuroinflammation (22.06.2016)
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