Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation
Howden, Andrew J. M., Hukelmann, Jens L., Brenes, Alejandro, Spinelli, Laura, Sinclair, Linda V., Lamond, Angus I., Cantrell, Doreen A.
Published in Nature immunology (01.11.2019)
Published in Nature immunology (01.11.2019)
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Antigen receptor control of methionine metabolism in T cells
Sinclair, Linda V, Howden, Andrew Jm, Brenes, Alejandro, Spinelli, Laura, Hukelmann, Jens L, Macintyre, Andrew N, Liu, Xiaojing, Thomson, Sarah, Taylor, Peter M, Rathmell, Jeffrey C, Locasale, Jason W, Lamond, Angus I, Cantrell, Doreen A
Published in eLife (27.03.2019)
Published in eLife (27.03.2019)
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The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human
Mir, Rafeeq, Tonelli, Francesca, Lis, Pawel, Macartney, Thomas, Polinski, Nicole K, Martinez, Terina N, Chou, Meng-Yun, Howden, Andrew J M, König, Theresa, Hotzy, Christoph, Milenkovic, Ivan, Brücke, Thomas, Zimprich, Alexander, Sammler, Esther, Alessi, Dario R
Published in Biochemical journal (06.06.2018)
Published in Biochemical journal (06.06.2018)
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Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils
Fan, Ying, Howden, Andrew J M, Sarhan, Adil R, Lis, Pawel, Ito, Genta, Martinez, Terina N, Brockmann, Kathrin, Gasser, Thomas, Alessi, Dario R, Sammler, Esther M
Published in Biochemical journal (15.01.2018)
Published in Biochemical journal (15.01.2018)
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Journal Article
Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation
Marchingo, Julia M, Sinclair, Linda V, Howden, Andrew Jm, Cantrell, Doreen A
Published in eLife (05.02.2020)
Published in eLife (05.02.2020)
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Journal Article
Genome-Scale Metabolic Model Accurately Predicts Fluxes in Central Carbon Metabolism under Stress Conditions
Williams, Thomas C.R, Poolman, Mark G, Howden, Andrew J.M, Schwarzlander, Markus, Fell, David A, Ratcliffe, R. George, Sweetlove, Lee J
Published in Plant physiology (Bethesda) (01.09.2010)
Published in Plant physiology (Bethesda) (01.09.2010)
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Journal Article
Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism
Watts, Emily R, Howden, Andrew Jm, Morrison, Tyler, Sadiku, Pranvera, Hukelmann, Jens, von Kriegsheim, Alex, Ghesquiere, Bart, Murphy, Fiona, Mirchandani, Ananda S, Humphries, Duncan C, Grecian, Robert, Ryan, Eilise M, Coelho, Patricia, Blanco, Gio Rodriguez, Plant, Tracie M, Dickinson, Rebecca S, Finch, Andy, Vermaelen, Wesley, Cantrell, Doreen A, Whyte, Moira K, Walmsley, Sarah R
Published in The Journal of clinical investigation (15.05.2021)
Published in The Journal of clinical investigation (15.05.2021)
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An integrated proteome and transcriptome of B cell maturation defines poised activation states of transitional and mature B cells
Salerno, Fiamma, Howden, Andrew J. M., Matheson, Louise S., Gizlenci, Özge, Screen, Michael, Lingel, Holger, Brunner-Weinzierl, Monika C., Turner, Martin
Published in Nature communications (23.08.2023)
Published in Nature communications (23.08.2023)
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Astrocyte-oligodendrocyte interaction regulates central nervous system regeneration
Molina-Gonzalez, Irene, Holloway, Rebecca K., Jiwaji, Zoeb, Dando, Owen, Kent, Sarah A., Emelianova, Katie, Lloyd, Amy F., Forbes, Lindsey H., Mahmood, Ayisha, Skripuletz, Thomas, Gudi, Viktoria, Febery, James A., Johnson, Jeffrey A., Fowler, Jill H., Kuhlmann, Tanja, Williams, Anna, Chandran, Siddharthan, Stangel, Martin, Howden, Andrew J. M., Hardingham, Giles E., Miron, Veronique E.
Published in Nature communications (08.06.2023)
Published in Nature communications (08.06.2023)
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Journal Article
Extensive acute and sustained changes to neutrophil proteomes post-SARS-CoV-2 infection
Long, Merete B, Howden, Andrew Jm, Keir, Holly R, Rollings, Christina M, Giam, Yan Hui, Pembridge, Thomas, Delgado, Lilia, Abo-Leyah, Hani, Lloyd, Amy F, Sollberger, Gabriel, Hull, Rebecca, Gilmour, Amy, Hughes, Chloe, New, Benjamin Jm, Cassidy, Diane, Shoemark, Amelia, Richardson, Hollian, Lamond, Angus I, Cantrell, Doreen A, Chalmers, James D, Brenes, Alejandro J
Published in The European respiratory journal (01.03.2024)
Published in The European respiratory journal (01.03.2024)
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Journal Article
AMPK integrates metabolite and kinase-based immunometabolic control in macrophages
Phair, Iain R., Nisr, Raid B., Howden, Andrew J.M., Sovakova, Magdalena, Alqurashi, Noor, Foretz, Marc, Lamont, Douglas, Viollet, Benoit, Rena, Graham
Published in Molecular metabolism (Germany) (01.02.2023)
Published in Molecular metabolism (Germany) (01.02.2023)
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Journal Article
NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease
Ryan, Eilise M, Sadiku, Pranvera, Coelho, Patricia, Watts, Emily R, Zhang, Ailiang, Howden, Andrew J M, Sanchez-Garcia, Manuel A, Bewley, Martin, Cole, Joby, McHugh, Brian J, Vermaelen, Wesley, Ghesquiere, Bart, Carmeliet, Peter, Rodriguez Blanco, Giovanny, Von Kriegsheim, Alex, Sanchez, Yolanda, Rumsey, William, Callahan, James F, Cooper, George, Parkinson, Nicholas, Baillie, Kenneth, Cantrell, Doreen A, McCafferty, John, Choudhury, Gourab, Singh, Dave, Dockrell, David H, Whyte, Moira K B, Walmsley, Sarah R
Published in American journal of respiratory and critical care medicine (15.04.2023)
Published in American journal of respiratory and critical care medicine (15.04.2023)
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Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses
Hodge, Suzanne H, Krauss, Maria Z, Kaymak, Irem, King, James I, Howden, Andrew J M, Panic, Gordana, Grencis, Richard K, Swann, Jonathan R, Sinclair, Linda V, Hepworth, Matthew R
Published in The Journal of experimental medicine (06.03.2023)
Published in The Journal of experimental medicine (06.03.2023)
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Journal Article
Phytophthora capsici-tomato interaction features dramatic shifts in gene expression associated with a hemi-biotrophic lifestyle
Jupe, Julietta, Stam, Remco, Howden, Andrew JM, Morris, Jenny A, Zhang, Runxuan, Hedley, Pete E, Huitema, Edgar
Published in Genome biology (25.06.2013)
Published in Genome biology (25.06.2013)
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Quantitative analysis of the tomato nuclear proteome during Phytophthora capsici infection unveils regulators of immunity
Howden, Andrew J. M., Stam, Remco, Martinez Heredia, Victor, Motion, Graham B., Have, Sara, Hodge, Kelly, Marques Monteiro Amaro, Tiago M., Huitema, Edgar
Published in The New phytologist (01.07.2017)
Published in The New phytologist (01.07.2017)
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