Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids
Roodhart, Jeanine M.L., Daenen, Laura G.M., Stigter, Edwin C.A., Prins, Henk-Jan, Gerrits, Johan, Houthuijzen, Julia M., Gerritsen, Marije G., Schipper, Henk S., Backer, Marieke J.G., van Amersfoort, Miranda, Vermaat, Joost S.P., Moerer, Petra, Ishihara, Kenji, Kalkhoven, Eric, Beijnen, Jos H., Derksen, Patrick W.B., Medema, Rene H., Martens, Anton C., Brenkman, Arjan B., Voest, Emile E.
Published in Cancer cell (13.09.2011)
Published in Cancer cell (13.09.2011)
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BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance
Duarte, Alexandra A, Gogola, Ewa, Sachs, Norman, Barazas, Marco, Annunziato, Stefano, R de Ruiter, Julian, Velds, Arno, Blatter, Sohvi, Houthuijzen, Julia M, van de Ven, Marieke, Clevers, Hans, Borst, Piet, Jonkers, Jos, Rottenberg, Sven
Published in Nature methods (01.02.2018)
Published in Nature methods (01.02.2018)
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CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer
Houthuijzen, Julia M., de Bruijn, Roebi, van der Burg, Eline, Drenth, Anne Paulien, Wientjens, Ellen, Filipovic, Tamara, Bullock, Esme, Brambillasca, Chiara S., Pulver, Emilia M., Nieuwland, Marja, de Rink, Iris, van Diepen, Frank, Klarenbeek, Sjoerd, Kerkhoven, Ron, Brunton, Valerie G., Scheele, Colinda L.G.J., Boelens, Mirjam C., Jonkers, Jos
Published in Nature communications (12.01.2023)
Published in Nature communications (12.01.2023)
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Journal Article
GREM1 signaling in cancer: tumor promotor and suppressor?
Gao, Zhichun, Houthuijzen, Julia M., ten Dijke, Peter, Brazil, Derek P.
Published in Journal of cell communication and signaling (01.12.2023)
Published in Journal of cell communication and signaling (01.12.2023)
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Metastasis of breast cancer to bones alters the tumor immune microenvironment
Chao, Xue, Zhang, Ying, Zheng, Chengyou, Huang, Qitao, Lu, Jiabin, Pulver, Emilia M, Houthuijzen, Julia, Hutten, Stefan, Luo, Rongzhen, He, Jiehua, Sun, Peng
Published in European journal of medical research (13.03.2023)
Published in European journal of medical research (13.03.2023)
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Journal Article
Lysophospholipids secreted by splenic macrophages induce chemotherapy resistance via interference with the DNA damage response
Houthuijzen, Julia M., Daenen, Laura G. M., Roodhart, Jeanine M. L., Oosterom, Ilse, van Jaarsveld, Marijn T. M., Govaert, Klaas M., Smith, Michelle E., Sadatmand, Sahar J., Rosing, Hilde, Kruse, Fabian, Helms, Bernd J., van Rooijen, Nico, Beijnen, Jos H., Haribabu, Bodduluri, van de Lest, Chris H. A., Voest, Emile E
Published in Nature communications (12.11.2014)
Published in Nature communications (12.11.2014)
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Fatty acid 16:4(n‐3) stimulates a GPR120‐induced signaling cascade in splenic macrophages to promote chemotherapy resistance
Houthuijzen, Julia M., Oosterom, Ilse, Hudson, Brian D., Hirasawa, Akira, Daenen, Laura G. M., McLean, Chelsea M., Hansen, Steffen V. F., Jaarsveld, Marijn T. M., Peeper, Daniel S., Sadatmand, Sahar Jafari, Roodhart, Jeanine M. L., Lest, Chris H. A., Ulven, Trond, Ishihara, Kenji, Milligan, Graeme, Voest, Emile E.
Published in The FASEB journal (01.05.2017)
Published in The FASEB journal (01.05.2017)
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Amygdala 14-3-3ζ as a novel modulator of escalating alcohol intake in mice
Lesscher, Heidi M B, Houthuijzen, Julia M, Groot Koerkamp, Marian J, Holstege, Frank C P, Vanderschuren, Louk J M J
Published in PloS one (22.05.2012)
Published in PloS one (22.05.2012)
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Phase I study of combined indomethacin and platinum-based chemotherapy to reduce platinum-induced fatty acids
van der Velden, Daphne L., Cirkel, Geert A., Houthuijzen, Julia M., van Werkhoven, E., Roodhart, Jeanine M. L., Daenen, Laura G. M., Kaing, Sovann, Gerrits, Johan, Verhoeven-Duif, Nanda M., Grootscholten, Cecile, Boot, Henk, Sessa, Cristisiana, Bloemendal, Haiko J., De Vos, Filip Y., Voest, Emile E.
Published in Cancer chemotherapy and pharmacology (01.05.2018)
Published in Cancer chemotherapy and pharmacology (01.05.2018)
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Increased Plasma Levels of Chemoresistance-Inducing Fatty Acid 16:4(n-3) After Consumption of Fish and Fish Oil
Daenen, Laura G M, Cirkel, Geert A, Houthuijzen, Julia M, Gerrits, Johan, Oosterom, Ilse, Roodhart, Jeanine M L, van Tinteren, Harm, Ishihara, Kenji, Huitema, Alwin D R, Verhoeven-Duif, Nanda M, Voest, Emile E
Published in JAMA oncology (01.06.2015)
Published in JAMA oncology (01.06.2015)
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Abstract A052: Dissecting the immune regulatory mechanisms of distinct PI3K alterations in invasive lobular carcinoma
van Weverwijk, Antoinette, Schubert, Michael, Siefert, Joseph, van Miltenburg, Martine, Vrijland, Kim, Houthuijzen, Julia, Stunnenberg, Anne, Hau, Cheei-Sing, Wessels, Lodewyk, Jonkers, Jos, de Visser, Karin E
Published in Cancer research (Chicago, Ill.) (01.02.2024)
Published in Cancer research (Chicago, Ill.) (01.02.2024)
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Abstract 307: GPR120/FFAR4 activation by fatty acid 16:4(n-3) plays a key role in resistance to chemotherapy
Houthuijzen, Julia, Oosterom, Ilse, Hudson, Brian, Hirasawa, Akira, Daenen, Laura, McLean, Chelsea, Hansen, Steffen, van Jaarsveld, Marijn, Peeper, Daniel, Jafari Sadatmand, sahar, Roodhart, Jeanine, van de Lest, Chris, Ulven, Trond, Ishihara, Kenji, Milligan, Graeme, Voest, Emile
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract 891: Platinum-induced fatty acids mediate resistance to DNA damaging agents via homologous recombination
Daenen, Laura GM, Houthuijzen, Julia M., Kruse, Fabian, Kersbergen, Ariena, Roodhart, Jeanine M.L., Rottenberg, Sven, Voest, Emile E.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Abstract 800: Formation of chemotherapy resistance-inducing fatty acids by mesenchymal stem cells depends on COX-1, thromboxane synthase and intracellular calcium
Houthuijzen, Julia M., Roodhart, Jeanine M.L., Daenen, Laura G.M., Voest, Emile E.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Abstract 3771: Splenic macrophages induce chemotherapy resistance via DNA damage repair
Houthuijzen, Julia M., Daenen, Laura G.M., Roodhart, Jeanine M.L., Govaert, Klaas M., Smith, Michelle E., Thomale, Juergen, Sadatmand, Sahar J., Rosing, Hilde, Kruse, Fabian, Rooijen, Nico van, Beijnen, Jos H., Borst, Piet, Rottenberg, Sven, Haribabu, Bodduluri, Voest, Emile E.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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