Confinement of Therapeutic Enzymes in Selectively Permeable Polymer Vesicles by Polymerization-Induced Self-Assembly (PISA) Reduces Antibody Binding and Proteolytic Susceptibility
Blackman, Lewis D, Varlas, Spyridon, Arno, Maria C, Houston, Zachary H, Fletcher, Nicholas L, Thurecht, Kristofer J, Hasan, Muhammad, Gibson, Matthew I, O’Reilly, Rachel K
Published in ACS central science (27.06.2018)
Published in ACS central science (27.06.2018)
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Journal Article
Direct Comparison of Poly(ethylene glycol) and Phosphorylcholine Drug-Loaded Nanoparticles In Vitro and In Vivo
Noy, Janina-Miriam, Chen, Fan, Akhter, Dewan T, Houston, Zachary H, Fletcher, Nicholas L, Thurecht, Kristofer J, Stenzel, Martina H
Published in Biomacromolecules (08.06.2020)
Published in Biomacromolecules (08.06.2020)
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Journal Article
Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery
Goswami, Lalit N., Houston, Zachary H., Sarma, Saurav J., Jalisatgi, Satish S., Hawthorne, M. Frederick
Published in Organic & biomolecular chemistry (21.02.2013)
Published in Organic & biomolecular chemistry (21.02.2013)
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Journal Article
Innovative Therapeutic Strategies for Effective Treatment of Brain Metastases
Lim, Malcolm, Puttick, Simon, Houston, Zachary H, Thurecht, Kristofer J, Kalita-de Croft, Priyakshi, Mahler, Stephen, Rose, Stephen E, Jeffree, Rosalind L, Mazzieri, Roberta, Dolcetti, Riccardo, Lakhani, Sunil R, Saunus, Jodi M
Published in International journal of molecular sciences (14.03.2019)
Published in International journal of molecular sciences (14.03.2019)
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Journal Article
Understanding the Uptake of Nanomedicines at Different Stages of Brain Cancer Using a Modular Nanocarrier Platform and Precision Bispecific Antibodies
Houston, Zachary H, Bunt, Jens, Chen, Kok-Siong, Puttick, Simon, Howard, Christopher B, Fletcher, Nicholas L, Fuchs, Adrian V, Cui, Jiwei, Ju, Yi, Cowin, Gary, Song, Xin, Boyd, Andrew W, Mahler, Stephen M, Richards, Linda J, Caruso, Frank, Thurecht, Kristofer J
Published in ACS central science (27.05.2020)
Published in ACS central science (27.05.2020)
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Journal Article
Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab® antibody against glypican-1 (GPC-1)
Yeh, Mei-Chun, Tse, Brian W. C., Fletcher, Nicholas L., Houston, Zachary H., Lund, Maria, Volpert, Marianna, Stewart, Chelsea, Sokolowski, Kamil A., Jeet, Varinder, Thurecht, Kristofer J., Campbell, Douglas H., Walsh, Bradley J., Nelson, Colleen C., Russell, Pamela J.
Published in EJNMMI research (07.05.2020)
Published in EJNMMI research (07.05.2020)
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Journal Article
Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract
dos Santos, Aline Martins, Meneguin, Andréia Bagliotti, Akhter, Dewan Taslima, Fletcher, Nicholas, Houston, Zachary H., Bell, Craig, Thurecht, Kristofer J., Gremião, Maria Palmira Daflon
Published in European journal of pharmaceutics and biopharmaceutics (01.01.2021)
Published in European journal of pharmaceutics and biopharmaceutics (01.01.2021)
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Journal Article
Exploring the impact of severity in hepatic fibrosis disease on the intrahepatic distribution of novel biodegradable nanoparticles targeted towards different disease biomarkers
Balaji, Arunpandian, Bell, Craig A., Houston, Zachary H., Bridle, Kim R., Genz, Berit, Fletcher, Nicholas L., Ramm, Grant A., Thurecht, Kristofer J.
Published in Biomaterials (01.11.2023)
Published in Biomaterials (01.11.2023)
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Journal Article
Controlling the Biological Fate of Micellar Nanoparticles: Balancing Stealth and Targeting
Sivaram, Amal J, Wardiana, Andri, Alcantara, Sheilajen, Sonderegger, Stefan E, Fletcher, Nicholas L, Houston, Zachary H, Howard, Christopher B, Mahler, Stephen M, Alexander, Cameron, Kent, Stephen J, Bell, Craig A, Thurecht, Kristofer J
Published in ACS nano (27.10.2020)
Published in ACS nano (27.10.2020)
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Journal Article
Evaluation of the in vivo fate of ultrapure alginate in a BALB/c mouse model
A, Anitha, Fletcher, Nicholas L., Houston, Zachary H., Thurecht, Kristofer J., Grøndahl, Lisbeth
Published in Carbohydrate polymers (15.06.2021)
Published in Carbohydrate polymers (15.06.2021)
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Journal Article
Localised delivery of doxorubicin to prostate cancer cells through a PSMA-targeted hyperbranched polymer theranostic
Pearce, Amanda K., Simpson, Joshua D., Fletcher, Nicholas L., Houston, Zachary H., Fuchs, Adrian V., Russell, Pamela J., Whittaker, Andrew K., Thurecht, Kristofer J.
Published in Biomaterials (01.10.2017)
Published in Biomaterials (01.10.2017)
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Journal Article
Development and Validation of a Targeted Treatment for Brain Tumors Using a Multi-Drug Loaded, Relapse-Resistant Polymeric Theranostic
Chu, Weijing, Houston, Zachary H., Fletcher, Nicholas L., Huda, Pie, Ahamed, Muneer, Lim, Ting Xiang, Day, Bryan W., Pinkham, Mark, Thurecht, Kristofer J.
Published in Biomacromolecules (12.06.2023)
Published in Biomacromolecules (12.06.2023)
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Journal Article
Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A Structure–Activity Comparison of Biodistribution
Humphries, James, Pizzi, David, Sonderegger, Stefan E, Fletcher, Nicholas L, Houston, Zachary H, Bell, Craig A, Kempe, Kristian, Thurecht, Kristofer J
Published in Biomacromolecules (10.08.2020)
Published in Biomacromolecules (10.08.2020)
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Journal Article
Ultrasound-responsive nanobubbles for enhanced intravitreal drug migration: An ex vivo evaluation
Thakur, Sachin S., Chen, Ying-Shan, Houston, Zachary H., Fletcher, Nicholas, Barnett, Nigel L., Thurecht, Kristofer J., Rupenthal, Ilva D., Parekh, Harendra S.
Published in European journal of pharmaceutics and biopharmaceutics (01.03.2019)
Published in European journal of pharmaceutics and biopharmaceutics (01.03.2019)
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Journal Article
Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation
Cifuentes-Rius, Anna, Ivask, Angela, Das, Shreya, Penya-Auladell, Nuria, Fabregas, Laura, Fletcher, Nicholas L, Houston, Zachary H, Thurecht, Kristofer J, Voelcker, Nicolas H
Published in ACS applied materials & interfaces (29.11.2017)
Published in ACS applied materials & interfaces (29.11.2017)
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Journal Article
A first-in-class dual-chelator theranostic agent designed for use with imaging-therapy radiometal pairs of different elements
Wood, James L, Ghosh, Saikat, Houston, Zachary H, Fletcher, Nicholas L, Humphries, James, Mardon, Karine, Akhter, Dewan T, Tieu, William, Ivashkevich, Alesia, Wheatcroft, Michael P, Thurecht, Kristofer J, Codd, Rachel
Published in Chemical science (Cambridge) (31.07.2024)
Published in Chemical science (Cambridge) (31.07.2024)
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Journal Article
Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption
Janowicz, Phillip W., Houston, Zachary H., Bunt, Jens, Fletcher, Nicholas L., Bell, Craig A., Cowin, Gary, Howard, Christopher B., Taslima, Dewan, Westra van Holthe, Nicholas, Prior, Amber, Soh, Vanessa, Ghosh, Saikat, Humphries, James, Huda, Pie, Mahler, Stephen M., Richards, Linda J., Thurecht, Kristofer J.
Published in Biomaterials (01.04.2022)
Published in Biomaterials (01.04.2022)
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Journal Article
Poly(2-ethyl-2-oxazoline) bottlebrushes: How nanomaterial dimensions can influence biological interactions
Pizzi, David, Mahmoud, Ayaat M., Klein, Tobias, Morrow, Joshua P., Humphries, James, Houston, Zachary H., Fletcher, Nicholas L., Bell, Craig A., Thurecht, Kristofer J., Kempe, Kristian
Published in European polymer journal (15.05.2021)
Published in European polymer journal (15.05.2021)
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Journal Article
Using Peptide Aptamer Targeted Polymers as a Model Nanomedicine for Investigating Drug Distribution in Cancer Nanotheranostics
Zhao, Yongmei, Houston, Zachary H, Simpson, Joshua D, Chen, Liyu, Fletcher, Nicholas L, Fuchs, Adrian V, Blakey, Idriss, Thurecht, Kristofer J
Published in Molecular pharmaceutics (02.10.2017)
Published in Molecular pharmaceutics (02.10.2017)
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Journal Article