Structural analysis of leader peptide binding enables leader-free cyanobactin processing
Koehnke, Jesko, Mann, Greg, Bent, Andrew F, Ludewig, Hannes, Shirran, Sally, Botting, Catherine, Lebl, Tomas, Houssen, Wael E, Jaspars, Marcel, Naismith, James H
Published in Nature chemical biology (01.08.2015)
Published in Nature chemical biology (01.08.2015)
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N‑Prenylation of Tryptophan by an Aromatic Prenyltransferase from the Cyanobactin Biosynthetic Pathway
Dalponte, Luca, Parajuli, Anirudra, Younger, Ellen, Mattila, Antti, Jokela, Jouni, Wahlsten, Matti, Leikoski, Niina, Sivonen, Kaarina, Jarmusch, Scott A, Houssen, Wael E, Fewer, David P
Published in Biochemistry (Easton) (18.12.2018)
Published in Biochemistry (Easton) (18.12.2018)
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The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain
Koehnke, Jesko, Bent, Andrew, Houssen, Wael E, Zollman, David, Morawitz, Falk, Shirran, Sally, Vendome, Jeremie, Nneoyiegbe, Ada F, Trembleau, Laurent, Botting, Catherine H, Smith, Margaret C M, Jaspars, Marcel, Naismith, James H
Published in Nature structural & molecular biology (01.08.2012)
Published in Nature structural & molecular biology (01.08.2012)
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The structural biology of patellamide biosynthesis
Koehnke, Jesko, Bent, Andrew F, Houssen, Wael E, Mann, Greg, Jaspars, Marcel, Naismith, James H
Published in Current opinion in structural biology (01.12.2014)
Published in Current opinion in structural biology (01.12.2014)
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An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides
Houssen, Wael E., Bent, Andrew F., McEwan, Andrew R., Pieiller, Nathalie, Tabudravu, Jioji, Koehnke, Jesko, Mann, Greg, Adaba, Rosemary I., Thomas, Louise, Hawas, Usama W., Liu, Huanting, Schwarz-Linek, Ulrich, Smith, Margaret C. M., Naismith, James H., Jaspars, Marcel
Published in Angewandte Chemie International Edition (15.12.2014)
Published in Angewandte Chemie International Edition (15.12.2014)
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Isolation and anti-HIV-1 integrase activity of lentzeosides A–F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude Atacama Desert soil
Wichner, Dominik, Idris, Hamidah, Houssen, Wael E, McEwan, Andrew R, Bull, Alan T, Asenjo, Juan A, Goodfellow, Michael, Jaspars, Marcel, Ebel, Rainer, Rateb, Mostafa E
Published in Journal of antibiotics (01.04.2017)
Published in Journal of antibiotics (01.04.2017)
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The Discovery of New Cyanobactins from Cyanothece PCC 7425 Defines a New Signature for Processing of Patellamides
Houssen, Wael E., Koehnke, Jesko, Zollman, David, Vendome, Jeremie, Raab, Andrea, Smith, Margaret C. M., Naismith, James H., Jaspars, Marcel
Published in Chembiochem : a European journal of chemical biology (21.12.2012)
Published in Chembiochem : a European journal of chemical biology (21.12.2012)
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Bioguided discovery and pharmacophore modeling of the mycotoxic indole diterpene alkaloids penitrems as breast cancer proliferation, migration, and invasion inhibitors
Sallam, Asmaa A, Houssen, Wael E, Gissendanner, Chris R, Orabi, Khaled Y, Foudah, Ahmed I, El Sayed, Khalid A
Published in MedChemComm (01.10.2013)
Published in MedChemComm (01.10.2013)
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Spongionella secondary metabolites protect mitochondrial function in cortical neurons against oxidative stress
Leirós, Marta, Sánchez, Jon A, Alonso, Eva, Rateb, Mostafa E, Houssen, Wael E, Ebel, Rainer, Jaspars, Marcel, Alfonso, Amparo, Botana, Luis M
Published in Marine drugs (27.01.2014)
Published in Marine drugs (27.01.2014)
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Spongionella Secondary Metabolites Regulate Store Operated Calcium Entry Modulating Mitochondrial Functioning in SH-SY5Y Neuroblastoma Cells
Sánchez, Jon Andoni, Alfonso, Amparo, Leirós, Marta, Alonso, Eva, Rateb, Mostafa E., Jaspars, Marcel, Houssen, Wael E., Ebel, Rainer, Botana, Luís M.
Published in Cellular physiology and biochemistry (01.01.2015)
Published in Cellular physiology and biochemistry (01.01.2015)
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Spongionella Secondary Metabolites, Promising Modulators of Immune Response through CD147 Receptor Modulation
Sánchez, Jon Andoni, Alfonso, Amparo, Rodriguez, Ines, Alonso, Eva, Cifuentes, José Manuel, Bermudez, Roberto, Rateb, Mostafa E, Jaspars, Marcel, Houssen, Wael E, Ebel, Rainer, Tabudravu, Jioji, Botana, Luís M
Published in Frontiers in immunology (24.10.2016)
Published in Frontiers in immunology (24.10.2016)
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Solution Structure of the Leader Sequence of the Patellamide Precursor Peptide, PatE1-34
Houssen , Wael E., Wright, Stephen H., Kalverda, Arnout P., Thompson, Gary S., Kelly, Sharon M., Jaspars, Marcel
Published in Chembiochem : a European journal of chemical biology (03.09.2010)
Published in Chembiochem : a European journal of chemical biology (03.09.2010)
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Chemoenzymatic Late‐Stage Modifications Enable Downstream Click‐Mediated Fluorescent Tagging of Peptides
Colombano, Alessandro, Dalponte, Luca, Dall'Angelo, Sergio, Clemente, Claudia, Idress, Mohannad, Ghazal, Ahmad, Houssen, Wael E.
Published in Angewandte Chemie International Edition (11.04.2023)
Published in Angewandte Chemie International Edition (11.04.2023)
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SARS‐CoV‐2 Spike Protein‐Derived Cyclic Peptides as Modulators of Spike Interaction with GRP78
Johnson, Nicholas, Pattinson, Craig, Burgoyne, Kate, Hijazi, Karolin, Houssen, Wael E., Milne, Bruce F.
Published in Chembiochem : a European journal of chemical biology (17.06.2024)
Published in Chembiochem : a European journal of chemical biology (17.06.2024)
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Biochemical characterization of a cyanobactin arginine- N -prenylase from the autumnalamide biosynthetic pathway
Clemente, Claudia, Johnson, Nicholas, Ouyang, Xiaodan, Popin, Rafael V., Dall'Angelo, Sergio, Wahlsten, Matti, Jokela, Jouni, Colombano, Alessandro, Nardone, Brunello, Fewer, David P., Houssen, Wael E.
Published in Chemical communications (Cambridge, England) (27.10.2022)
Published in Chemical communications (Cambridge, England) (27.10.2022)
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Exploring the Limits of Cyanobactin Macrocyclase PatGmac: Cyclization of PawS-Derived Peptide Sunflower Trypsin Inhibitor‑1 and Cyclotide Kalata B1
Muhammad, Taj, Houssen, Wael E, Thomas, Louise, Alexandru-Crivac, Cristina-Nicoleta, Gunasekera, Sunithi, Jaspars, Marcel, Göransson, Ulf
Published in Journal of natural products (Washington, D.C.) (24.03.2023)
Published in Journal of natural products (Washington, D.C.) (24.03.2023)
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