Evaluation of serum bile acid profiles as biomarkers of liver injury in rodents
Luo, Lina, Schomaker, Shelli, Houle, Christopher, Aubrecht, Jiri, Colangelo, Jennifer L
Published in Toxicological sciences (01.01.2014)
Published in Toxicological sciences (01.01.2014)
Get full text
Journal Article
Discovery and Preclinical Profiling of 3‑[4-(Morpholin-4-yl)‑7H‑pyrrolo[2,3‑d]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant, and in Vivo Active LRRK2 Kinase Inhibitor
Henderson, Jaclyn L., Kormos, Bethany L., Hayward, Matthew M., Coffman, Karen J., Jasti, Jayasankar, Kurumbail, Ravi G., Wager, Travis T., Verhoest, Patrick R., Noell, G. Stephen, Chen, Yi, Needle, Elie, Berger, Zdenek, Steyn, Stefanus J., Houle, Christopher, Hirst, Warren D., Galatsis, Paul
Published in Journal of medicinal chemistry (08.01.2015)
Published in Journal of medicinal chemistry (08.01.2015)
Get full text
Journal Article
Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors
Zuhl, Andrea M, Nolan, Charles E, Brodney, Michael A, Niessen, Sherry, Atchison, Kevin, Houle, Christopher, Karanian, David A, Ambroise, Claude, Brulet, Jeffrey W, Beck, Elizabeth M, Doran, Shawn D, O'Neill, Brian T, Am Ende, Christopher W, Chang, Cheng, Geoghegan, Kieran F, West, Graham M, Judkins, Joshua C, Hou, Xinjun, Riddell, David R, Johnson, Douglas S
Published in Nature communications (11.10.2016)
Published in Nature communications (11.10.2016)
Get full text
Journal Article
Publication Categories in Toxicologic Pathology
Boyle, Molly H, Bennet, Bindu, Colman, Karyn, Frisk, Anna-Lena, Garcia, Begonya, Houle, Christopher D, Romeike, Annette, Sura, Radhakrishna, Werner, Jonathan, Elmore, Susan A
Published in Toxicologic pathology (01.07.2021)
Published in Toxicologic pathology (01.07.2021)
Get more information
Journal Article
Perspectives on drug-induced vascular injury
Morton, Daniel, Houle, Christopher D, Tomlinson, Lindsay
Published in Toxicologic pathology (01.06.2014)
Published in Toxicologic pathology (01.06.2014)
Get more information
Journal Article
Effects of lersivirine on canine and rodent thyroid function
Houle, Christopher D, Finch, Gregory L, Mauthe, Robert J, Potter, David M, Walisser, Jacqueline A, Gardner, Iain B, DeWit, Robert H
Published in Toxicologic pathology (01.07.2014)
Published in Toxicologic pathology (01.07.2014)
Get more information
Journal Article
Histologic and cytologic detection of endocrine and reproductive tract effects of exemestane in female rats treated for up to twenty-eight days
Mirsky, Michael L, Sivaraman, Lakshmi, Houle, Christopher, Potter, David M, Chapin, Robert E, Cappon, Gregg D
Published in Toxicologic pathology (01.06.2011)
Published in Toxicologic pathology (01.06.2011)
Get more information
Journal Article
Loss of Expression and Altered Localization of KAI1 and CD9 Protein Are Associated with Epithelial Ovarian Cancer Progression
Houle, Christopher D., Ding, Xiao-Yu, Foley, Julie F., Afshari, Cynthia A., Barrett, J.Carl, Davis, Barbara J.
Published in Gynecologic oncology (01.07.2002)
Published in Gynecologic oncology (01.07.2002)
Get full text
Journal Article
Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens oxazepam and Wyeth-14,643
Iida, Mari, Anna, Colleen H., Hartis, Jennifer, Bruno, Maribel, Wetmore, Barbara, Dubin, Joshua R., Sieber, Stella, Bennett, Lee, Cunningham, Michael L., Paules, Richard S., Tomer, Kenneth B., Houle, Christopher D., Merrick, Alex B., Sills, Robert C., Devereux, Theodora R.
Published in Carcinogenesis (New York) (01.04.2003)
Published in Carcinogenesis (New York) (01.04.2003)
Get full text
Journal Article
K-ras mutations in lung tumors and tumors from other organs are consistent with a common mechanism of ethylene oxide tumorigenesis in the B6C3F1 mouse
Hong, Hue-Hua L, Houle, Christopher D, Ton, Thai-Vu T, Sills, Robert C
Published in Toxicologic pathology (01.01.2007)
Published in Toxicologic pathology (01.01.2007)
Get more information
Journal Article
Frequent p53 and H-ras mutations in benzene- and ethylene oxide-induced mammary gland carcinomas from B6C3F1 mice
Houle, Christopher D, Ton, Thai-Vu T, Clayton, Natasha, Huff, James, Hong, Hue-Hua L, Sills, Robert C
Published in Toxicologic pathology (01.10.2006)
Published in Toxicologic pathology (01.10.2006)
Get more information
Journal Article
Spontaneous and irradiation-induced tumor susceptibility in BRCA2 germline mutant mice and cooperative effects with a p53 germline mutation
McAllister, Kimberly A, Houle, Christopher D, Malphurs, Jason, Ward, Toni, Collins, N Keith, Gersch, William, Wharey, Laura, Seely, John C, Betz, Laura, Bennett, L Michelle, Wiseman, Roger W, Davis, Barbara J
Published in Toxicologic pathology (01.01.2006)
Published in Toxicologic pathology (01.01.2006)
Get more information
Journal Article
Cardiovascular Involvement in 8 Dogs with Blastomyces Dermatitidis Infection
Schmiedt, C, Kellum, H, Legendre, A.M, Gompf, R.E, Bright, J.M, Houle, C.D, Schutten, M, Stepien, R
Published in Journal of veterinary internal medicine (01.11.2006)
Published in Journal of veterinary internal medicine (01.11.2006)
Get full text
Journal Article
LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits
Baptista, Marco A S, Merchant, Kalpana, Barrett, Ted, Bhargava, Sakshi, Bryce, Dianne K, Ellis, J Michael, Estrada, Anthony A, Fell, Matthew J, Fiske, Brian K, Fuji, Reina N, Galatsis, Paul, Henry, Anastasia G, Hill, Sue, Hirst, Warren, Houle, Christopher, Kennedy, Matthew E, Liu, Xingrong, Maddess, Matthew L, Markgraf, Carrie, Mei, Hong, Meier, William A, Needle, Elie, Ploch, Stephen, Royer, Christopher, Rudolph, Karin, Sharma, Alok K, Stepan, Antonia, Steyn, Stefan, Trost, Craig, Yin, Zhizhang, Yu, Hongshi, Wang, Xiang, Sherer, Todd B
Published in Science translational medicine (22.04.2020)
Published in Science translational medicine (22.04.2020)
Get more information
Journal Article
Mutant Brca2/ p53 mice exhibit altered radiation responses in the developing mammary gland
Houle, Christopher D., Peddada, Shyamal D., McAllister, Kimberly A., Ward, Toni, Malphurs, Jason, Gersch, William D., Davis, Barbara J.
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.11.2005)
Published in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie (01.11.2005)
Get full text
Journal Article
Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators
Shah, Falgun, Stepan, Antonia F., O'Mahony, Alison, Velichko, Sharlene, Folias, Alexandra E., Houle, Christopher, Shaffer, Christopher L., Marcek, John, Whritenour, Jessica, Stanton, Robert, Berg, Ellen L.
Published in Cell chemical biology (20.07.2017)
Published in Cell chemical biology (20.07.2017)
Get full text
Journal Article