The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression
Espiritu, Shadrielle Melijah G., Liu, Lydia Y., Rubanova, Yulia, Bhandari, Vinayak, Holgersen, Erle M., Szyca, Lesia M., Fox, Natalie S., Chua, Melvin L.K., Yamaguchi, Takafumi N., Heisler, Lawrence E., Livingstone, Julie, Wintersinger, Jeff, Yousif, Fouad, Lalonde, Emilie, Rouette, Alexandre, Salcedo, Adriana, Houlahan, Kathleen E., Li, Constance H., Huang, Vincent, Fraser, Michael, van der Kwast, Theodorus, Morris, Quaid D., Bristow, Robert G., Boutros, Paul C.
Published in Cell (03.05.2018)
Published in Cell (03.05.2018)
Get full text
Journal Article
Deterministic evolution and stringent selection during preneoplasia
Karlsson, Kasper, Przybilla, Moritz J, Kotler, Eran, Khan, Aziz, Xu, Hang, Karagyozova, Kremena, Sockell, Alexandra, Wong, Wing H, Liu, Katherine, Mah, Amanda, Lo, Yuan-Hung, Lu, Bingxin, Houlahan, Kathleen E, Ma, Zhicheng, Suarez, Carlos J, Barnes, Chris P, Kuo, Calvin J, Curtis, Christina
Published in Nature (London) (08.06.2023)
Published in Nature (London) (08.06.2023)
Get full text
Journal Article
Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer
Lee, Joyce V., Housley, Filomena, Yau, Christina, Nakagawa, Rachel, Winkler, Juliane, Anttila, Johanna M., Munne, Pauliina M., Savelius, Mariel, Houlahan, Kathleen E., Van de Mark, Daniel, Hemmati, Golzar, Hernandez, Grace A., Zhang, Yibing, Samson, Susan, Baas, Carole, Kok, Marleen, Esserman, Laura J., van ‘t Veer, Laura J., Rugo, Hope S., Curtis, Christina, Klefström, Juha, Matloubian, Mehrdad, Goga, Andrei
Published in Nature communications (27.06.2022)
Published in Nature communications (27.06.2022)
Get full text
Journal Article
MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability
Dingar, Dharmendra, Tu, William B, Resetca, Diana, Lourenco, Corey, Tamachi, Aaliya, De Melo, Jason, Houlahan, Kathleen E, Kalkat, Manpreet, Chan, Pak-Kei, Boutros, Paul C, Raught, Brian, Penn, Linda Z
Published in Nature communications (29.08.2018)
Published in Nature communications (29.08.2018)
Get full text
Journal Article
Germline-mediated immunoediting sculpts breast cancer subtypes and metastatic proclivity
Houlahan, Kathleen E, Khan, Aziz, Greenwald, Noah F, Vivas, Cristina Sotomayor, West, Robert B, Angelo, Michael, Curtis, Christina
Published in Science (American Association for the Advancement of Science) (31.05.2024)
Published in Science (American Association for the Advancement of Science) (31.05.2024)
Get full text
Journal Article
Molecular Hallmarks of Multiparametric Magnetic Resonance Imaging Visibility in Prostate Cancer
Houlahan, Kathleen E., Salmasi, Amirali, Sadun, Taylor Y., Pooli, Aydin, Felker, Ely R., Livingstone, Julie, Huang, Vincent, Raman, Steven S., Ahuja, Preeti, Sisk, Anthony E., Boutros, Paul C., Reiter, Robert E.
Published in European urology (01.07.2019)
Published in European urology (01.07.2019)
Get full text
Journal Article
Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection
Ewing, Adam D, Houlahan, Kathleen E, Hu, Yin, Ellrott, Kyle, Caloian, Cristian, Yamaguchi, Takafumi N, Bare, J Christopher, P'ng, Christine, Waggott, Daryl, Sabelnykova, Veronica Y, Kellen, Michael R, Norman, Thea C, Haussler, David, Friend, Stephen H, Stolovitzky, Gustavo, Margolin, Adam A, Stuart, Joshua M, Boutros, Paul C
Published in Nature methods (01.07.2015)
Published in Nature methods (01.07.2015)
Get full text
Journal Article
Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH
Hung, King L, Luebeck, Jens, Dehkordi, Siavash R, Colón, Caterina I, Li, Rui, Wong, Ivy Tsz-Lo, Coruh, Ceyda, Dharanipragada, Prashanthi, Lomeli, Shirley H, Weiser, Natasha E, Moriceau, Gatien, Zhang, Xiao, Bailey, Chris, Houlahan, Kathleen E, Yang, Wenting, González, Rocío Chamorro, Swanton, Charles, Curtis, Christina, Jamal-Hanjani, Mariam, Henssen, Anton G, Law, Julie A, Greenleaf, William J, Lo, Roger S, Mischel, Paul S, Bafna, Vineet, Chang, Howard Y
Published in Nature genetics (01.11.2022)
Published in Nature genetics (01.11.2022)
Get full text
Journal Article
Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts
Strand, Siri H., Rivero-Gutiérrez, Belén, Houlahan, Kathleen E., Seoane, Jose A., King, Lorraine M., Risom, Tyler, Simpson, Lunden A., Vennam, Sujay, Khan, Aziz, Cisneros, Luis, Hardman, Timothy, Harmon, Bryan, Couch, Fergus, Gallagher, Kristalyn, Kilgore, Mark, Wei, Shi, DeMichele, Angela, King, Tari, McAuliffe, Priscilla F., Nangia, Julie, Lee, Joanna, Tseng, Jennifer, Storniolo, Anna Maria, Thompson, Alastair M., Gupta, Gaorav P., Burns, Robyn, Veis, Deborah J., DeSchryver, Katherine, Zhu, Chunfang, Matusiak, Magdalena, Wang, Jason, Zhu, Shirley X., Tappenden, Jen, Ding, Daisy Yi, Zhang, Dadong, Luo, Jingqin, Jiang, Shu, Varma, Sushama, Anderson, Lauren, Straub, Cody, Srivastava, Sucheta, Curtis, Christina, Tibshirani, Rob, Angelo, Robert Michael, Hall, Allison, Owzar, Kouros, Polyak, Kornelia, Maley, Carlo, Marks, Jeffrey R., Colditz, Graham A., Hwang, E. Shelley, West, Robert B.
Published in Cancer cell (12.12.2022)
Published in Cancer cell (12.12.2022)
Get full text
Journal Article
Analysis of ductal carcinoma in situ by self-reported race reveals molecular differences related to outcome
Strand, Siri H., Houlahan, Kathleen E., Branch, Vernal, Lynch, Thomas, Rivero-Guitiérrez, Belén, Harmon, Bryan, Couch, Fergus, Gallagher, Kristalyn, Kilgore, Mark, Wei, Shi, DeMichele, Angela, King, Tari, McAuliffe, Priscilla, Curtis, Christina, Owzar, Kouros, Marks, Jeffrey R., Colditz, Graham A., Hwang, E. Shelley, West, Robert B.
Published in Breast cancer research : BCR (02.09.2024)
Published in Breast cancer research : BCR (02.09.2024)
Get full text
Journal Article
The landscape of RNA polymerase II-associated chromatin interactions in prostate cancer
Ramanand, Susmita G, Chen, Yong, Yuan, Jiapei, Daescu, Kelly, Lambros, Maryou Bk, Houlahan, Kathleen E, Carreira, Suzanne, Yuan, Wei, Baek, GuemHee, Sharp, Adam, Paschalis, Alec, Kanchwala, Mohammed, Gao, Yunpeng, Aslam, Adam, Safdar, Nida, Zhan, Xiaowei, Raj, Ganesh V, Xing, Chao, Boutros, Paul C, de Bono, Johann, Zhang, Michael Q, Mani, Ram S
Published in The Journal of clinical investigation (01.08.2020)
Published in The Journal of clinical investigation (01.08.2020)
Get full text
Journal Article
Genome-wide germline correlates of the epigenetic landscape of prostate cancer
Houlahan, Kathleen E, Shiah, Yu-Jia, Gusev, Alexander, Yuan, Jiapei, Ahmed, Musaddeque, Shetty, Anamay, Ramanand, Susmita G, Yao, Cindy Q, Bell, Connor, O'Connor, Edward, Huang, Vincent, Fraser, Michael, Heisler, Lawrence E, Livingstone, Julie, Yamaguchi, Takafumi N, Rouette, Alexandre, Foucal, Adrien, Espiritu, Shadrielle Melijah G, Sinha, Ankit, Sam, Michelle, Timms, Lee, Johns, Jeremy, Wong, Ada, Murison, Alex, Orain, Michèle, Picard, Valérie, Hovington, Hélène, Bergeron, Alain, Lacombe, Louis, Lupien, Mathieu, Fradet, Yves, Têtu, Bernard, McPherson, John D, Pasaniuc, Bogdan, Kislinger, Thomas, Chua, Melvin L K, Pomerantz, Mark M, van der Kwast, Theodorus, Freedman, Matthew L, Mani, Ram S, He, Housheng H, Bristow, Robert G, Boutros, Paul C
Published in Nature medicine (01.10.2019)
Published in Nature medicine (01.10.2019)
Get full text
Journal Article
Insights on Future Directions in Cancer Research from the AACR NextGen Stars
Cañadas, Israel, Casirati, Gabriele, Houlahan, Kathleen E., Maxwell, Kara N., Mehta, Arnav, Parolia, Abhijit, Saulnier, Olivier, Taylor, Alison M., Thomas, Claire E., Vázquez-García, Ignacio
Published in Cancer discovery (04.09.2024)
Published in Cancer discovery (04.09.2024)
Get full text
Journal Article
Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer
Lee, Joyce V., Housley, Filomena, Yau, Christina, Nakagawa, Rachel, Winkler, Juliane, Anttila, Johanna M., Munne, Pauliina M., Savelius, Mariel, Houlahan, Kathleen E., Van de Mark, Daniel, Hemmati, Golzar, Hernandez, Grace A., Zhang, Yibing, Samson, Susan, Baas, Carole, Kok, Marleen, Esserman, Laura J., van ‘t Veer, Laura J., Rugo, Hope S., Curtis, Christina, Klefström, Juha, Matloubian, Mehrdad, Goga, Andrei
Published in Nature communications (21.11.2022)
Published in Nature communications (21.11.2022)
Get full text
Journal Article
CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer
Ahmed, Musaddeque, Soares, Fraser, Xia, Ji-Han, Yang, Yue, Li, Jing, Guo, Haiyang, Su, Peiran, Tian, Yijun, Lee, Hyung Joo, Wang, Miranda, Akhtar, Nayeema, Houlahan, Kathleen E, Bosch, Almudena, Zhou, Stanley, Mazrooei, Parisa, Hua, Junjie T, Chen, Sujun, Petricca, Jessica, Zeng, Yong, Davies, Alastair, Fraser, Michael, Quigley, David A, Feng, Felix Y, Boutros, Paul C, Lupien, Mathieu, Zoubeidi, Amina, Wang, Liang, Walsh, Martin J, Wang, Ting, Ren, Shancheng, Wei, Gong-Hong, He, Housheng Hansen
Published in Nature communications (19.03.2021)
Published in Nature communications (19.03.2021)
Get full text
Journal Article
A polygenic two-hit hypothesis for prostate cancer
Houlahan, Kathleen E, Livingstone, Julie, Fox, Natalie S, Kurganovs, Natalie, Zhu, Helen, Sietsma Penington, Jocelyn, Jung, Chol-Hee, Yamaguchi, Takafumi N, Heisler, Lawrence E, Jovelin, Richard, Costello, Anthony J, Pope, Bernard J, Kishan, Amar U, Corcoran, Niall M, Bristow, Robert G, Waszak, Sebastian M, Weischenfeldt, Joachim, He, Housheng H, Hung, Rayjean J, Hovens, Christopher M, Boutros, Paul C
Published in JNCI : Journal of the National Cancer Institute (11.04.2023)
Published in JNCI : Journal of the National Cancer Institute (11.04.2023)
Get full text
Journal Article
Prostate Cancer Transcriptomic Regulation by the Interplay of Germline Risk Alleles, Somatic Mutations, and 3D Genomic Architecture
Yuan, Jiapei, Houlahan, Kathleen E, Ramanand, Susmita G, Lee, Sora, Baek, GuemHee, Yang, Yang, Chen, Yong, Strand, Douglas W, Zhang, Michael Q, Boutros, Paul C, Mani, Ram S
Published in Cancer discovery (02.12.2022)
Published in Cancer discovery (02.12.2022)
Get full text
Journal Article
Modelling the MYC-driven normal-to-tumour switch in breast cancer
Lourenco, Corey, Kalkat, Manpreet, Houlahan, Kathleen E, De Melo, Jason, Longo, Joseph, Done, Susan J, Boutros, Paul C, Penn, Linda Z
Published in Disease models & mechanisms (01.07.2019)
Published in Disease models & mechanisms (01.07.2019)
Get full text
Journal Article