Search Results - "Houghten Richard A" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

The value of antimicrobial peptides in the age of resistance

The value of antimicrobial peptides in the age of resistance

by Magana, Maria, Pushpanathan, Muthuirulan, Santos, Ana L, Leanse, Leon, Fernandez, Michael, Ioannidis, Anastasios, Giulianotti, Marc A, Apidianakis, Yiorgos, Bradfute, Steven, Ferguson, Andrew L, Cherkasov, Artem, Seleem, Mohamed N, Pinilla, Clemencia, de la Fuente-Nunez, Cesar, Lazaridis, Themis, Dai, Tianhong, Houghten, Richard A, Hancock, Robert E W, Tegos, George P
Published in The Lancet infectious diseases (01.09.2020)

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Shifting from the single to the multitarget paradigm in drug discovery

Shifting from the single to the multitarget paradigm in drug discovery

by Medina-Franco, José L., Giulianotti, Marc A., Welmaker, Gregory S., Houghten, Richard A.
Published in Drug discovery today (01.05.2013)

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Mu-Opioid receptor biased ligands: A safer and painless discovery of analgesics?

Mu-Opioid receptor biased ligands: A safer and painless discovery of analgesics?

by Madariaga-Mazón, Abraham, Marmolejo-Valencia, Andrés F., Li, Yangmei, Toll, Lawrence, Houghten, Richard A., Martinez-Mayorga, Karina
Published in Drug discovery today (01.11.2017)

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Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide

Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide

by Li, Yangmei, Eans, Shainnel O, Ganno-Sherwood, Michelle, Eliasof, Abbe, Houghten, Richard A, McLaughlin, Jay P
Published in Molecules (Basel, Switzerland) (01.11.2023)

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Integrating virtual screening and combinatorial chemistry for accelerated drug discovery

Integrating virtual screening and combinatorial chemistry for accelerated drug discovery

by López-Vallejo, Fabian, Caulfield, Thomas, Martínez-Mayorga, Karina, Giulianotti, Marc A, Nefzi, Adel, Houghten, Richard A, Medina-Franco, Jose L
Published in Combinatorial chemistry & high throughput screening (01.07.2011)

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The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (MC3R) Small-Molecule Ligands

The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (MC3R) Small-Molecule Ligands

by Ericson, Mark D, Freeman, Katie T, LaVoi, Travis M, Donow, Haley M, Santos, Radleigh G, Giulianotti, Marc A, Pinilla, Clemencia, Houghten, Richard A, Haskell-Luevano, Carrie
Published in International journal of molecular sciences (14.06.2023)

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Discovery of Novel Inhibitors of a Disintegrin and Metalloprotease 17 (ADAM17) Using Glycosylated and Non-glycosylated Substrates

Discovery of Novel Inhibitors of a Disintegrin and Metalloprotease 17 (ADAM17) Using Glycosylated and Non-glycosylated Substrates

by Minond, Dmitriy, Cudic, Mare, Bionda, Nina, Giulianotti, Marc, Maida, Laura, Houghten, Richard A., Fields, Gregg B.
Published in The Journal of biological chemistry (19.10.2012)

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Chemoinformatic Analysis of Combinatorial Libraries, Drugs, Natural Products, and Molecular Libraries Small Molecule Repository

Chemoinformatic Analysis of Combinatorial Libraries, Drugs, Natural Products, and Molecular Libraries Small Molecule Repository

by Singh, Narender, Guha, Rajarshi, Giulianotti, Marc A, Pinilla, Clemencia, Houghten, Richard A, Medina-Franco, Jose L
Published in Journal of Chemical Information and Modeling (27.04.2009)

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Identification of a Novel Polyamine Scaffold With Potent Efflux Pump Inhibition Activity Toward Multi-Drug Resistant Bacterial Pathogens

Identification of a Novel Polyamine Scaffold With Potent Efflux Pump Inhibition Activity Toward Multi-Drug Resistant Bacterial Pathogens

by Fleeman, Renee M, Debevec, Ginamarie, Antonen, Kirsten, Adams, Jessie L, Santos, Radleigh G, Welmaker, Gregory S, Houghten, Richard A, Giulianotti, Marc A, Shaw, Lindsey N
Published in Frontiers in microbiology (14.06.2018)

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Activity of ADAM17 (a Disintegrin and Metalloprotease 17) Is Regulated by Its Noncatalytic Domains and Secondary Structure of its Substrates

Activity of ADAM17 (a Disintegrin and Metalloprotease 17) Is Regulated by Its Noncatalytic Domains and Secondary Structure of its Substrates

by Stawikowska, Roma, Cudic, Mare, Giulianotti, Marc, Houghten, Richard A., Fields, Gregg B., Minond, Dmitriy
Published in The Journal of biological chemistry (02.08.2013)

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Novel Cyclic Lipopeptides Fusaricidin Analogs for Treating Wound Infections

Novel Cyclic Lipopeptides Fusaricidin Analogs for Treating Wound Infections

by Gil, Joel, Pastar, Irena, Houghten, Richard A, Padhee, Shruti, Higa, Alexander, Solis, Michael, Valdez, Jose, Head, Cheyanne R, Michaels, Heather, Lenhart, Brian, Simms, Colin, Williams, Brandon, Cudic, Predrag, Davis, Stephen C
Published in Frontiers in microbiology (23.07.2021)

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A Novel Probe for Spliceosomal Proteins that Induces Autophagy and Death of Melanoma Cells Reveals New Targets for Melanoma Drug Discovery

A Novel Probe for Spliceosomal Proteins that Induces Autophagy and Death of Melanoma Cells Reveals New Targets for Melanoma Drug Discovery

by Palrasu, Manikandan, Knapinska, Anna M, Diez, Juan, Smith, Lyndsay, LaVoi, Travis, Giulianotti, Marc, Houghten, Richard A, Fields, Gregg B, Minond, Dmitriy
Published in Cellular physiology and biochemistry (2019)

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Palladium-Catalyzed C–H Functionalization Using Guanidine as a Directing Group: Ortho Arylation and Olefination of Arylguanidines

Palladium-Catalyzed C–H Functionalization Using Guanidine as a Directing Group: Ortho Arylation and Olefination of Arylguanidines

by Shao, Jiaan, Chen, Wenteng, Giulianotti, Marc A, Houghten, Richard A, Yu, Yongping
Published in Organic letters (02.11.2012)

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A traceless approach to amide and peptide construction from thioacids and dithiocarbamate-terminal amines

A traceless approach to amide and peptide construction from thioacids and dithiocarbamate-terminal amines

by Chen, Wenteng, Shao, Jiaan, Hu, Miao, Yu, Wanwan, Giulianotti, Marc A, Houghten, Richard A, Yu, Yongping
Published in Chemical science (Cambridge) (01.01.2013)

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Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity

by Schimmer, Aaron D., Welsh, Kate, Pinilla, Clemencia, Wang, Zhiliang, Krajewska, Maryla, Bonneau, Marie-Josee, Pedersen, Irene M., Kitada, Shinichi, Scott, Fiona L., Bailly-Maitre, Beatrice, Glinsky, Gennadi, Scudiero, Dominick, Sausville, Edward, Salvesen, Guy, Nefzi, Adel, Ostresh, John M., Houghten, Richard A., Reed, John C.
Published in Cancer cell (2004)

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The Current Status of Heterocyclic Combinatorial Libraries

The Current Status of Heterocyclic Combinatorial Libraries

by Nefzi, Adel, Ostresh, John M, Houghten, Richard A
Published in Chemical reviews (01.04.1997)

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Short Polybasic Peptide Sequences Are Potent Inhibitors of PC5/6 and PC7: Use of Positional Scanning-Synthetic Peptide Combinatorial Libraries as a Tool for the Optimization of Inhibitory Sequences

Short Polybasic Peptide Sequences Are Potent Inhibitors of PC5/6 and PC7: Use of Positional Scanning-Synthetic Peptide Combinatorial Libraries as a Tool for the Optimization of Inhibitory Sequences

by Fugere, Martin, Appel, Jon, Houghten, Richard A, Lindberg, Iris, Day, Robert
Published in Molecular pharmacology (01.01.2007)

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Combinatorial Chemistry: Libraries from Libraries, the Art of the Diversity-Oriented Transformation of Resin-Bound Peptides and Chiral Polyamides to Low Molecular Weight Acyclic and Heterocyclic Compounds

Combinatorial Chemistry: Libraries from Libraries, the Art of the Diversity-Oriented Transformation of Resin-Bound Peptides and Chiral Polyamides to Low Molecular Weight Acyclic and Heterocyclic Compounds

by Nefzi, Adel, Ostresh, John M, Yu, Jongping, Houghten, Richard A
Published in Journal of organic chemistry (28.05.2004)

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Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells

Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells

by Carter, Bing Z., Gronda, Marcela, Wang, Zhiliang, Welsh, Kate, Pinilla, Clemencia, Andreeff, Michael, Schober, Wendy D., Nefzi, Adel, Pond, Gregory R., Mawji, Imtiaz A., Houghten, Richard A., Ostresh, John, Brandwein, Joseph, Minden, Mark D., Schuh, Andre C., Wells, Richard A., Messner, Hans, Chun, Kathy, Reed, John C., Schimmer, Aaron D.
Published in Blood (15.05.2005)

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The mathematics of a successful deconvolution: a quantitative assessment of mixture-based combinatorial libraries screened against two formylpeptide receptors

The mathematics of a successful deconvolution: a quantitative assessment of mixture-based combinatorial libraries screened against two formylpeptide receptors

by Santos, Radleigh G, Appel, Jon R, Giulianotti, Marc A, Edwards, Bruce S, Sklar, Larry A, Houghten, Richard A, Pinilla, Clemencia
Published in Molecules (Basel, Switzerland) (30.05.2013)

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