Catalytic efficiency and kcat / KM : a useful comparator?
Eisenthal, Robert, Danson, Michael J, Hough, David W
Published in Trends in biotechnology (Regular ed.) (01.06.2007)
Published in Trends in biotechnology (Regular ed.) (01.06.2007)
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Efficacy and safety of paliperidone palmitate in adult patients with acutely symptomatic schizophrenia: a randomized, double-blind, placebo-controlled, dose-response study
Gopal, Srihari, Hough, David W, Xu, Haiyan, Lull, Julia M, Gassmann-Mayer, Cristiana, Remmerie, Bart M, Eerdekens, Marielle H, Brown, David W
Published in International clinical psychopharmacology (01.09.2010)
Published in International clinical psychopharmacology (01.09.2010)
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Metabolism of Pentose Sugars in the Hyperthermophilic Archaea Sulfolobus solfataricus and Sulfolobus acidocaldarius
Nunn, Charlotte E.M., Johnsen, Ulrike, Schönheit, Peter, Fuhrer, Tobias, Sauer, Uwe, Hough, David W., Danson, Michael J.
Published in The Journal of biological chemistry (29.10.2010)
Published in The Journal of biological chemistry (29.10.2010)
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Paliperidone extended-release as adjunctive therapy to lithium or valproate in the treatment of acute mania: A randomized, placebo-controlled study
Berwaerts, Joris, Lane, Rosanne, Nuamah, Isaac F, Lim, Pilar, Remmerie, Bart, Hough, David W
Published in Journal of affective disorders (01.03.2011)
Published in Journal of affective disorders (01.03.2011)
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A randomized, placebo- and active-controlled study of paliperidone extended release for the treatment of acute manic and mixed episodes of bipolar I disorder
Vieta, Eduard, Nuamah, Isaac F, Lim, Pilar, Yuen, Eric C, Palumbo, Joseph M, Hough, David W, Berwaerts, Joris
Published in Bipolar disorders (01.05.2010)
Published in Bipolar disorders (01.05.2010)
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Metabolic Pathway Promiscuity in the Archaeon Sulfolobus solfataricus Revealed by Studies on Glucose Dehydrogenase and 2-Keto-3-deoxygluconate Aldolase
Lamble, Henry J., Heyer, Narinder I., Bull, Steven D., Hough, David W., Danson, Michael J.
Published in The Journal of biological chemistry (05.09.2003)
Published in The Journal of biological chemistry (05.09.2003)
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Structurally Informed Site-Directed Mutagenesis of a Stereochemically Promiscuous Aldolase To Afford Stereochemically Complementary Biocatalysts
Royer, Sylvain F., Haslett, Luke, Crennell, Susan J., Hough, David W., Danson, Michael J., Bull, Steven D.
Published in Journal of the American Chemical Society (25.08.2010)
Published in Journal of the American Chemical Society (25.08.2010)
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Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex
Marrott, Nia L, Marshall, Jacqueline J T, Svergun, Dmitri I, Crennell, Susan J, Hough, David W, van den Elsen, Jean M H, Danson, Michael J
Published in Biochemical journal (01.11.2014)
Published in Biochemical journal (01.11.2014)
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A one-year prospective study of the safety, tolerability and pharmacokinetics of the highest available dose of paliperidone palmitate in patients with schizophrenia
Coppola, Danielle, Liu, Yanning, Gopal, Srihari, Remmerie, Bart, Samtani, Mahesh N, Hough, David W, Nuamah, Isaac, Sulaiman, Ahmad, Pandina, Gahan
Published in BMC psychiatry (28.03.2012)
Published in BMC psychiatry (28.03.2012)
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Structural adaptations of the cold-active citrate synthase from an Antarctic bacterium
Russell, Rupert JM, Gerike, Ursula, Danson, Michael J, Hough, David W, Taylor, Garry L
Published in Structure (London) (15.03.1998)
Published in Structure (London) (15.03.1998)
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Efficacy and Safety of the 3-Month Formulation of Paliperidone Palmitate vs Placebo for Relapse Prevention of Schizophrenia: A Randomized Clinical Trial
Berwaerts, Joris, Liu, Yanning, Gopal, Srihari, Nuamah, Isaac, Xu, Haiyan, Savitz, Adam, Coppola, Danielle, Schotte, Alain, Remmerie, Bart, Maruta, Nataliya, Hough, David W
Published in JAMA psychiatry (Chicago, Ill.) (01.08.2015)
Published in JAMA psychiatry (Chicago, Ill.) (01.08.2015)
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The Structural Basis for Substrate Promiscuity in 2-Keto-3-deoxygluconate Aldolase from the Entner-Doudoroff Pathway in Sulfolobus solfataricus
Theodossis, Alex, Walden, Helen, Westwick, Elaine J, Connaris, Helen, Lamble, Henry J, Hough, David W, Danson, Michael J, Taylor, Garry L
Published in The Journal of biological chemistry (15.10.2004)
Published in The Journal of biological chemistry (15.10.2004)
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Gluconate dehydratase from the promiscuous Entner–Doudoroff pathway in Sulfolobus solfataricus
Lamble, Henry J., Milburn, Christine C., Taylor, Garry L., Hough, David W., Danson, Michael J.
Published in FEBS letters (08.10.2004)
Published in FEBS letters (08.10.2004)
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Promiscuity in the part-phosphorylative Entner–Doudoroff pathway of the archaeon Sulfolobus solfataricus
Lamble, Henry J., Theodossis, Alex, Milburn, Christine C., Taylor, Garry L., Bull, Steven D., Hough, David W., Danson, Michael J.
Published in FEBS letters (19.12.2005)
Published in FEBS letters (19.12.2005)
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Evaluation of the effect of paliperidone extended release and quetiapine on corrected QT intervals: a randomized, double-blind, placebo-controlled study
Hough, David W, Natarajan, Jaya, Vandebosch, An, Rossenu, Stefan, Kramer, Michelle, Eerdekens, Mariëlle
Published in International clinical psychopharmacology (01.01.2011)
Published in International clinical psychopharmacology (01.01.2011)
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The Structural Basis of Substrate Promiscuity in Glucose Dehydrogenase from the Hyperthermophilic Archaeon Sulfolobus solfataricus
Milburn, Christine C., Lamble, Henry J., Theodossis, Alex, Bull, Steven D., Hough, David W., Danson, Michael J., Taylor, Garry L.
Published in The Journal of biological chemistry (26.05.2006)
Published in The Journal of biological chemistry (26.05.2006)
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