Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents
Tari, Leslie W, Li, Xiaoming, Trzoss, Michael, Bensen, Daniel C, Chen, Zhiyong, Lam, Thanh, Zhang, Junhu, Lee, Suk Joong, Hough, Grayson, Phillipson, Doug, Akers-Rodriguez, Suzanne, Cunningham, Mark L, Kwan, Bryan P, Nelson, Kirk J, Castellano, Amanda, Locke, Jeff B, Brown-Driver, Vickie, Murphy, Timothy M, Ong, Voon S, Pillar, Chris M, Shinabarger, Dean L, Nix, Jay, Lightstone, Felice C, Wong, Sergio E, Nguyen, Toan B, Shaw, Karen J, Finn, John
Published in PloS one (26.12.2013)
Published in PloS one (26.12.2013)
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Identification of Bacteria-Selective Threonyl-tRNA Synthetase Substrate Inhibitors by Structure-Based Design
Teng, Min, Hilgers, Mark T, Cunningham, Mark L, Borchardt, Allen, Locke, Jeffrey B, Abraham, Sunny, Haley, Gregory, Kwan, Bryan P, Hall, Courtney, Hough, Grayson W, Shaw, Karen J, Finn, John
Published in Journal of medicinal chemistry (28.02.2013)
Published in Journal of medicinal chemistry (28.02.2013)
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Isolation of Apoptosis-Inducing Stilbenoids from Four Members of the Orchidaceae Family
Williams, Russell B, Martin, Steven M, Hu, Jin-Feng, Garo, Eliane, Rice, Stephanie M, Norman, Vanessa L, Lawrence, Julie A, Hough, Grayson W, Goering, Matt G, O'Neil-Johnson, Mark, Eldridge, Gary R, Starks, Courtney M
Published in Planta medica (2012)
Published in Planta medica (2012)
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Antibacterial clerodane diterpenes from Goldenrod ( Solidago virgaurea)
Starks, Courtney M., Williams, Russell B., Goering, Matt G., O’Neil-Johnson, Mark, Norman, Vanessa L., Hu, Jin-Feng, Garo, Eliane, Hough, Grayson W., Rice, Stephanie M., Eldridge, Gary R.
Published in Phytochemistry (Oxford) (2010)
Published in Phytochemistry (Oxford) (2010)
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Journal Article
Bacterial biofilm inhibitors from Diospyros dendo
Hu, J.F, Garo, E, Goering, M.G, Pasmore, M, Yoo, H.D, Esser, T, Sestrich, J, Cremin, P.A, Hough, G.W, Perrone, P
Published in Journal of natural products (Washington, D.C.) (01.01.2006)
Published in Journal of natural products (Washington, D.C.) (01.01.2006)
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Secoiridoid Glycosides from the Pitcher Plant Sarracenia alata
Hu, Jin-Feng, Starks, Courtney M., Williams, Russell B., Rice, Stephanie M., Norman, Vanessa L., Olson, Krista M., Hough, Grayson W., Goering, Matt G., O'Neil-Johnson, Mark, Eldridge, Gary R.
Published in Helvetica chimica acta (01.02.2009)
Published in Helvetica chimica acta (01.02.2009)
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Dammarane-Type Triterpene Glycosides from Oncoba manii Active against Methicillin-Resistant Staphylococcus aureus
Garo, Eliane, Hung, Chia S, Williams, Russell B, Olson, Krista M, Hu, Jin-Feng, Rice, Stephanie M, Hough, Grayson W, Goering, Matt G, O'Neil-Johnson, Mark, Eldridge, Gary R, Starks, Courtney M
Published in Planta medica (01.04.2009)
Published in Planta medica (01.04.2009)
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Anti-HCV Bioactivity of Pseudoguaianolides from Parthenium hispitum
Hu, Jin-Feng, Patel, Rupal, Li, Bin, Garo, Eliane, Hough, Grayson W, Goering, Matt G, Yoo, Hye-Dong, O'Neil-Johnson, Mark, Eldridge, Gary R
Published in Journal of natural products (Washington, D.C.) (01.04.2007)
Published in Journal of natural products (Washington, D.C.) (01.04.2007)
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Preclinical Evaluation of the Stability, Safety, and Efficacy of CD101, a Novel Echinocandin
Ong, Voon, Hough, Grayson, Schlosser, Michael, Bartizal, Ken, Balkovec, James M, James, Kenneth D, Krishnan, B Radha
Published in Antimicrobial agents and chemotherapy (01.11.2016)
Published in Antimicrobial agents and chemotherapy (01.11.2016)
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Bacterial Biofilm Inhibitors from Diospyros d endo
Hu, Jin-Feng, Garo, Eliane, Goering, Matt G, Pasmore, Mark, Yoo, Hye-Dong, Esser, Tim, Sestrich, Jennifer, Cremin, Peadar A, Hough, Grayson W, Perrone, Peter, Lee, Yin-Shi L, Le, Ngoc-Tram, O'Neil-Johnson, Mark, Costerton, John W, Eldridge, Gary R
Published in Journal of natural products (Washington, D.C.) (27.01.2006)
Published in Journal of natural products (Washington, D.C.) (27.01.2006)
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Journal Article
Laxanol, a new 2,5-diaryl-3,4-dihydroxymethyltetrahydrofuran type lignan from Justicia laxa
Hu, Jin-Feng, Starks, Courtney M., Garo, Eliane, Hough, Grayson W., Rice, Stephanie M., Goering, Matt G., O'Neil-Johnson, Mark, Eldridge, Gary R.
Published in Journal of chemical research (01.01.2008)
Published in Journal of chemical research (01.01.2008)
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Isoflavones from Psorothamnus arborescens via high-throughput natural product chemistry methods
Hu, Jin-Feng, Garo, Eliane, Hough, Grayson W., Goering, Matt G., Yoo, Hye-Dong, O'Neil-Johnson, Mark, Eldridge, Gary R.
Published in Journal of chemical research (01.05.2007)
Published in Journal of chemical research (01.05.2007)
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CD101: a novel long‐acting echinocandin
Zhao, Yanan, Perez, Winder B., Jiménez‐Ortigosa, Cristina, Hough, Grayson, Locke, Jeffrey B., Ong, Voon, Bartizal, Ken, Perlin, David S.
Published in Cellular microbiology (01.09.2016)
Published in Cellular microbiology (01.09.2016)
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Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7‑(Benzimidazol-1-yl)-2,4-diaminoquinazolines
Lam, Thanh, Hilgers, Mark T, Cunningham, Mark L, Kwan, Bryan P, Nelson, Kirk J, Brown-Driver, Vickie, Ong, Voon, Trzoss, Michael, Hough, Grayson, Shaw, Karen Joy, Finn, John
Published in Journal of medicinal chemistry (13.02.2014)
Published in Journal of medicinal chemistry (13.02.2014)
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Development of Novel Immunoprophylactic Agents against Multidrug-Resistant Gram-Negative Bacterial Infections
Lovey, Arianne, Krel, Mila, Borchardt, Allen, Brady, Thomas, Cole, Jason N, Do, Quyen-Quyen, Fortier, Joanne, Hough, Grayson, Jiang, Wanlong, Noncovich, Alain, Tari, Les, Zhao, Qiping, Balkovec, James M, Zhao, Yanan, Perlin, David S
Published in Antimicrobial agents and chemotherapy (18.10.2021)
Published in Antimicrobial agents and chemotherapy (18.10.2021)
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Journal Article
CTC-177, a novel drug–Fc conjugate, shows promise as an immunoprophylactic agent against multidrug-resistant Gram-negative bacterial infections
Lovey, Arianne, Lee, Annie, Yu, Allison, Krel, Mila, Wang, Mingming, Paderu, Padmaja, Brady, Thomas, Hough, Grayson, Zhao, Qiping, Balkovec, James M, Perlin, David S, Zhao, Yanan
Published in JAC-antimicrobial resistance (01.08.2024)
Published in JAC-antimicrobial resistance (01.08.2024)
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Abstract LB131: CBO421, a novel drug Fc-conjugate, inhibits the enzymatic activity of CD73 and triggers CD73 internalization
Abelovski, Elizabeth, Dedeic, Nicholas, Döhrmann, Simon, Levin, James, Almaguer, Amanda, Zuill, Doug, Fortier, Joanne, Zhao, Qiping, Hernandez, Maria, Amundson, Karin, Moniz, Madison, Chen, Hongyuan, Panickar, Dhanya, Lam, Thanh, Brady, Tom, Borchardt, Allen, Hough, Grayson, Locke, Jeffrey B., Cole, Jason N., Tari, Leslie W.
Published in Cancer research (Chicago, Ill.) (05.04.2024)
Published in Cancer research (Chicago, Ill.) (05.04.2024)
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Abstract 2668: CBO421: A novel drug Fc-conjugate to prevent tumor immune evasion via the CD73/adenosine pathway
Almaguer, Amanda, Zuill, Doug, Döhrmann, Simon, Levin, James, Dedeic, Nicholas, Abelovski, Elizabeth, Fortier, Joanne, Zhao, Qiping, Hernandez, Maria, Amundson, Karin, Moniz, Madison, Chen, Hongyuan, Panickar, Dhanya, Lam, Thanh, Brady, Tom, Borchardt, Allen, Hough, Grayson, Locke, Jeffrey B., Cole, Jason N., Tari, Leslie W.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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