Simlukafusp alfa (FAP-IL2v) immunocytokine is a versatile combination partner for cancer immunotherapy
Waldhauer, Inja, Gonzalez-Nicolini, Valeria, Freimoser-Grundschober, Anne, Nayak, Tapan K, Fahrni, Linda, Hosse, Ralf J, Gerrits, Danny, Geven, Edwin J W, Sam, Johannes, Lang, Sabine, Bommer, Esther, Steinhart, Virginie, Husar, Elisabeth, Colombetti, Sara, Van Puijenbroek, Erwin, Neubauer, Markus, Cline, J Mark, Garg, Pradeep K, Dugan, Gregory, Cavallo, Federica, Acuna, Gonzalo, Charo, Jehad, Teichgräber, Volker, Evers, Stefan, Boerman, Otto C, Bacac, Marina, Moessner, Ekkehard, Umaña, Pablo, Klein, Christian
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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RG7386, a Novel Tetravalent FAP-DR5 Antibody, Effectively Triggers FAP-Dependent, Avidity-Driven DR5 Hyperclustering and Tumor Cell Apoptosis
Brünker, Peter, Wartha, Katharina, Friess, Thomas, Grau-Richards, Sandra, Waldhauer, Inja, Koller, Claudia Ferrara, Weiser, Barbara, Majety, Meher, Runza, Valeria, Niu, Huifeng, Packman, Kathryn, Feng, Ningping, Daouti, Sherif, Hosse, Ralf J, Mössner, Ekkehard, Weber, Thomas G, Herting, Frank, Scheuer, Werner, Sade, Hadassah, Shao, Cuiying, Liu, Bin, Wang, Peng, Xu, Gary, Vega-Harring, Suzana, Klein, Christian, Bosslet, Klaus, Umaña, Pablo
Published in Molecular cancer therapeutics (01.05.2016)
Published in Molecular cancer therapeutics (01.05.2016)
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Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity
Wang, Chun Jing, Petersone, Lina, Edner, Natalie M., Heuts, Frank, Ovcinnikovs, Vitalijs, Ntavli, Elisavet, Kogimtzis, Alexandros, Fabri, Astrid, Elfaki, Yassin, Houghton, Luke P., Hosse, Ralf J., Schubert, David A., Frei, Andreas P., Ross, Ellen M., Walker, Lucy S. K.
Published in Nature communications (09.11.2022)
Published in Nature communications (09.11.2022)
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Author Correction: Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity
Wang, Chun Jing, Petersone, Lina, Edner, Natalie M., Heuts, Frank, Ovcinnikovs, Vitalijs, Ntavli, Elisavet, Kogimtzis, Alexandros, Fabri, Astrid, Elfaki, Yassin, Houghton, Luke P., Hosse, Ralf J., Schubert, David A., Frei, Andreas P., Ross, Ellen M., Walker, Lucy S. K.
Published in Nature communications (15.09.2023)
Published in Nature communications (15.09.2023)
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Characterization of anti-drug antibody responses to the T-cell engaging bispecific antibody cibisatamab to understand the impact on exposure
Lotz, Gregor P, Lutz, Achim, Martin-Facklam, Meret, Hansbauer, Andre, Schick, Eginhard, Moessner, Ekkehard, Antony, Michael, Stuchly, Thomas, Viert, Maria, Hosse, Ralf J, Freimoser-Grundschober, Anne, Klein, Christian, Schäfer, Martin, Ritter, Mirko, Stubenrauch, Kay-Gunnar
Published in Frontiers in immunology (31.05.2024)
Published in Frontiers in immunology (31.05.2024)
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A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors
Bacac, Marina, Fauti, Tanja, Sam, Johannes, Colombetti, Sara, Weinzierl, Tina, Ouaret, Djamila, Bodmer, Walter, Lehmann, Steffi, Hofer, Thomas, Hosse, Ralf J, Moessner, Ekkehard, Ast, Oliver, Bruenker, Peter, Grau-Richards, Sandra, Schaller, Teilo, Seidl, Annette, Gerdes, Christian, Perro, Mario, Nicolini, Valeria, Steinhoff, Nathalie, Dudal, Sherri, Neumann, Sebastian, von Hirschheydt, Thomas, Jaeger, Christiane, Saro, Jose, Karanikas, Vaios, Klein, Christian, Umaña, Pablo
Published in Clinical cancer research (01.07.2016)
Published in Clinical cancer research (01.07.2016)
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Target Expression, Generation, Preclinical Activity, and Pharmacokinetics of the BCMA-T Cell Bispecific Antibody EM801 for Multiple Myeloma Treatment
Seckinger, Anja, Delgado, Jose Antonio, Moser, Samuel, Moreno, Laura, Neuber, Brigitte, Grab, Anna, Lipp, Susanne, Merino, Juana, Prosper, Felipe, Emde, Martina, Delon, Camille, Latzko, Melanie, Gianotti, Reto, Lüoend, Remo, Murr, Ramona, Hosse, Ralf J., Harnisch, Lydia Jasmin, Bacac, Marina, Fauti, Tanja, Klein, Christian, Zabaleta, Aintzane, Hillengass, Jens, Cavalcanti-Adam, Elisabetta Ada, Ho, Anthony D., Hundemer, Michael, San Miguel, Jesus F., Strein, Klaus, Umaña, Pablo, Hose, Dirk, Paiva, Bruno, Vu, Minh Diem
Published in Cancer cell (13.03.2017)
Published in Cancer cell (13.03.2017)
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A long-lived IL-2 mutein that selectively activates and expands regulatory T cells as a therapy for autoimmune disease
Peterson, Laurence B., Bell, Charles J.M., Howlett, Sarah K., Pekalski, Marcin L., Brady, Kevin, Hinton, Heather, Sauter, Denise, Todd, John A., Umana, Pablo, Ast, Oliver, Waldhauer, Inja, Freimoser-Grundschober, Anne, Moessner, Ekkehard, Klein, Christian, Hosse, Ralf J., Wicker, Linda S.
Published in Journal of autoimmunity (01.12.2018)
Published in Journal of autoimmunity (01.12.2018)
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Excystation of Eimeria tenella Sporozoites Impaired by Antibody Recognizing Gametocyte/Oocyst Antigens GAM22 and GAM56
Krücken, Jürgen, Hosse, Ralf J, Mouafo, Aimdip N, Entzeroth, Rolf, Bierbaum, Stefan, Marinovski, Predrag, Hain, Karolina, Greif, Gisela, Wunderlich, Frank
Published in Eukaryotic Cell (01.02.2008)
Published in Eukaryotic Cell (01.02.2008)
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Immuno-PET and Immuno-SPECT of Rheumatoid Arthritis with Radiolabeled Anti-Fibroblast Activation Protein Antibody Correlates with Severity of Arthritis
Laverman, Peter, van der Geest, Tessa, Terry, Samantha Y A, Gerrits, Danny, Walgreen, Birgitte, Helsen, Monique M, Nayak, Tapan K, Freimoser-Grundschober, Anne, Waldhauer, Inja, Hosse, Ralf J, Moessner, Ekkehard, Umana, Pablo, Klein, Christian, Oyen, Wim J G, Koenders, Marije I, Boerman, Otto C
Published in Journal of Nuclear Medicine (01.05.2015)
Published in Journal of Nuclear Medicine (01.05.2015)
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Sustained in vivo signaling by long-lived IL-2 induces prolonged increases of regulatory T cells
Bell, Charles J.M, Sun, Yongliang, Nowak, Urszula M, Clark, Jan, Howlett, Sarah, Pekalski, Marcin L, Yang, Xin, Ast, Oliver, Waldhauer, Inja, Freimoser-Grundschober, Anne, Moessner, Ekkehard, Umana, Pablo, Klein, Christian, Hosse, Ralf J, Wicker, Linda S, Peterson, Laurence B
Published in Journal of autoimmunity (01.01.2015)
Published in Journal of autoimmunity (01.01.2015)
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XGFR, a novel affinity-matured bispecific antibody targeting IGF-1R and EGFR with combined signaling inhibition and enhanced immune activation for the treatment of pancreatic cancer
Schanzer, Juergen M, Wartha, Katharina, Moessner, Ekkehard, Hosse, Ralf J, Moser, Samuel, Croasdale, Rebecca, Trochanowska, Halina, Shao, Cuiying, Wang, Peng, Shi, Lei, Weinzierl, Tina, Rieder, Natascha, Bacac, Marina, Ries, Carola H, Kettenberger, Hubert, Schlothauer, Tilman, Friess, Thomas, Umana, Pablo, Klein, Christian
Published in mAbs (18.05.2016)
Published in mAbs (18.05.2016)
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Kinetic screening of antibody–Im7 conjugates by capture on a colicin E7 DNase domain using optical biosensors
Hosse, Ralf J., Tay, Leigh, Hattarki, Meghan K., Pontes-Braz, Luisa, Pearce, Lesley A., Nuttall, Stewart D., Dolezal, Olan
Published in Analytical biochemistry (15.02.2009)
Published in Analytical biochemistry (15.02.2009)
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Ribosome display for improved biotherapeutic molecules
Rothe, Achim, Hosse, Ralf J, Power, Barbara E
Published in Expert opinion on biological therapy (01.02.2006)
Published in Expert opinion on biological therapy (01.02.2006)
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Selection of human anti-CD28 scFvs from a T-NHL related scFv library using ribosome display
Rothe, Achim, Nathanielsz, Anne, Hosse, Ralf J., Oberhäuser, Frank, Strandmann, Elke P., Engert, Andreas, Hudson, Peter J., Power, Barbara E.
Published in Journal of biotechnology (15.07.2007)
Published in Journal of biotechnology (15.07.2007)
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Eimeria tenella: Genomic organization and expression of an 89 kDa cyclophilin
Hosse, Ralf J., Krücken, Jürgen, Bierbaum, Stefan, Greif, Gisela, Wunderlich, Frank
Published in Experimental parasitology (01.02.2008)
Published in Experimental parasitology (01.02.2008)
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Eimeria tenella: genomic organization and expression of an 89kDa cyclophilin
Hosse, Ralf J, Krücken, Jürgen, Bierbaum, Stefan, Greif, Gisela, Wunderlich, Frank
Published in Experimental parasitology (01.02.2008)
Published in Experimental parasitology (01.02.2008)
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Selection of Human Anti-CD22 scFvs from an Acute Lymphocytic Leukemia Related scFv Library with Ribosome Display
Rothe, Achim, Hosse, Ralf J., Nathanielsz, Anne, Oberhaeuser, Frank, von Strandmann, Elke Pogge, Engert, Andreas, Hudson, Peter J., Power, Barbara E.
Published in Blood (16.11.2006)
Published in Blood (16.11.2006)
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