Activating transcription factor 4 mediates hyperglycaemia-induced endothelial inflammation and retinal vascular leakage through activation of STAT3 in a mouse model of type 1 diabetes
Chen, Y., Wang, J. J., Li, J., Hosoya, K. I., Ratan, R., Townes, T., Zhang, S. X.
Published in Diabetologia (01.09.2012)
Published in Diabetologia (01.09.2012)
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Inhibition of TXNIP expression in vivo blocks early pathologies of diabetic retinopathy
Perrone, L, Devi, T S, Hosoya, K-I, Terasaki, T, Singh, L P
Published in Cell death & disease (01.08.2010)
Published in Cell death & disease (01.08.2010)
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mRna expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting
Hosoya, K I, Takashima, T, Tetsuka, K, Nagura, T, Ohtsuki, S, Takanaga, H, Ueda, M, Yanai, N, Obinata, M, Terasaki, T
Published in Journal of drug targeting (2000)
Published in Journal of drug targeting (2000)
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In-vivo and in-vitro evidence of a carrier-mediated efflux transport system for oestrone-3-sulphate across the blood-cerebrospinal fluid barrier
Kitazawa, T, Hosoya, K, Takahashi, T, Sugiyama, Y, Terasaki, T
Published in Journal of pharmacy and pharmacology (01.03.2000)
Published in Journal of pharmacy and pharmacology (01.03.2000)
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Journal Article
Acidic Amino Acid Transport Characteristics of a Newly Developed Conditionally Immortalized Rat Type 2 Astrocyte Cell Line (TR-AST)
Tetsuka, Kazuhiro, Hosoya, Ken-ichi, Ohtsuki, Sumio, Takanaga, Hitomi, Yanai, Nobuaki, Ueda, Masatsugu, Obinata, Masuo, Terasaki, Tetsuya
Published in Cell Structure and Function (01.08.2001)
Published in Cell Structure and Function (01.08.2001)
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Journal Article
Distribution of microsomal prostaglandin E synthase-1 in the mouse brain
Eskilsson, Anna, Tachikawa, Masanori, Hosoya, Ken-ichi, Blomqvist, Anders
Published in Journal of comparative neurology (1911) (01.10.2014)
Published in Journal of comparative neurology (1911) (01.10.2014)
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Role of blood–brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain
Ohtsuki, Sumio, Asaba, Hiroshi, Takanaga, Hitomi, Deguchi, Tsuneo, Hosoya, Ken‐ichi, Otagiri, Masaki, Terasaki, Tetsuya
Published in Journal of neurochemistry (01.10.2002)
Published in Journal of neurochemistry (01.10.2002)
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The structural barrier of absorptive mucosae: site difference of the permeability of fluorescein isothiocyanate-labelled dextran in rabbits
Hosoya, K, Kubo, H, Natsume, H, Sugibayashi, K, Morimoto, Y, Yamashita, S
Published in Biopharmaceutics & drug disposition (01.11.1993)
Published in Biopharmaceutics & drug disposition (01.11.1993)
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Conditionally Immortalized Retinal Capillary Endothelial Cell Lines (TR-iBRB) Expressing Differentiated Endothelial Cell Functions Derived from a Transgenic Rat
Hosoya, Ken-Ichi, Tomi, Masatoshi, Ohtsuki, Sumio, Takanaga, Hitomi, Ueda, Masatsugu, Yanai, Nobuaki, Obinata, Masuo, Terasaki, Tetsuya
Published in Experimental eye research (01.02.2001)
Published in Experimental eye research (01.02.2001)
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MCT1-mediated transport of L-lactic acid at the inner blood-retinal barrier: A possible route for delivery of monocarboxylic acid drugs to the retina
HOSOYA, Ken-Ichi, KONDO, Tetsu, TOMI, Masatoshi, TAKANAGA, Hitomi, OHTSUKI, Sumio, TERASAKI, Tetsuya
Published in Pharmaceutical research (01.12.2001)
Published in Pharmaceutical research (01.12.2001)
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Screening of cationic compounds as an absorption enhancer for nasal drug delivery
Natsume, Hideshi, Iwata, Satoko, Ohtake, Kazuo, Miyamoto, Misao, Yamaguchi, Masatoshi, Hosoya, Ken-ichi, Kobayashi, Daisuke, Sugibayashi, Kenji, Morimoto, Yasunori
Published in International journal of pharmaceutics (05.08.1999)
Published in International journal of pharmaceutics (05.08.1999)
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Internalization of basic fibroblast growth factor at the mouse blood–brain barrier involves perlecan, a heparan sulfate proteoglycan
Deguchi, Yoshiharu, Okutsu, Hiroshi, Okura, Takashi, Yamada, Shizuo, Kimura, Ryohei, Yuge, Takuro, Furukawa, Akihiko, Morimoto, Kazuhiro, Tachikawa, Masanori, Ohtsuki, Sumio, Hosoya, Ken‐ichi, Terasaki, Tetsuya
Published in Journal of neurochemistry (01.10.2002)
Published in Journal of neurochemistry (01.10.2002)
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Journal Article
Coordinating Etk/Bmx activation and VEGF upregulation to promote cell survival and proliferation
CHAU, Cindy H, CHEN, Kai-Yun, DENG, Hong-Tao, KIM, Kwang-Jin, HOSOYA, Ken-Ichi, TERASAKI, Tetsuya, SHIH, Hsiu-Ming, ANN, David K
Published in Oncogene (12.12.2002)
Published in Oncogene (12.12.2002)
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Characterization of the amino acid transport of new immortalized choroid plexus epithelial cell lines: A novel In vitro system for investigating transport functions at the blood-cerebrospinal fluid barrier
KITAZAWA, Takeo, HOSOYA, Ken-Ichi, WATANABE, Masatomi, TAKASHIMA, Tadayuki, OHTSUKI, Sumio, TAKANAGA, Hitomi, UEDA, Masatsugu, YANAI, Nobuaki, OBINATA, Masuo, TERASAKI, Tetsuya
Published in Pharmaceutical research (2001)
Published in Pharmaceutical research (2001)
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Blood-brain barrier transport of a novel mu sub(1)-specific opioid peptide, H-Tyr-d-Arg-Phe- beta -Ala-OH (TAPA)
Deguchi, Y, Miyakawa, Y, Sakurada, Sh, Naito, Y, Morimoto, K, Ohtsuki, S, Hosoya, K-I, Terasaki, T
Published in Journal of neurochemistry (01.03.2003)
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Published in Journal of neurochemistry (01.03.2003)
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