Titin function in the active sarcomere studied in frog muscle fibers upon inhibition of myosin motors by para-nitro-blebbistatin
Squarci, Caterina, Bianco, Pasquale, Reconditi, Massimo, Pertici, Irene, Caremani, Marco, Narayanan, Theyencheri, Horvath, Adam I., Malnasi-Csizmadia, Andras, Linari, Marco, Lombardi, Vincenzo, Piazzesi, Gabriella
Published in Biophysical journal (10.02.2023)
Published in Biophysical journal (10.02.2023)
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Journal Article
Titin activates myosin filaments in skeletal muscle by switching from an extensible spring to a mechanical rectifier
Squarci, Caterina, Bianco, Pasquale, Reconditi, Massimo, Pertici, Irene, Caremani, Marco, Narayanan, Theyencheri, Horváth, Ádám I, Málnási-Csizmadia, András, Linari, Marco, Lombardi, Vincenzo, Piazzesi, Gabriella
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2023)
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Journal Article
Myeloid Src-family kinases are critical for neutrophil-mediated autoinflammation in gout and motheaten models
Futosi, Krisztina, Németh, Tamás, Horváth, Ádám I, Abram, Clare L, Tusnády, Simon, Lowell, Clifford A, Helyes, Zsuzsanna, Mócsai, Attila
Published in The Journal of experimental medicine (03.07.2023)
Published in The Journal of experimental medicine (03.07.2023)
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Journal Article
Effect of allosteric inhibition of non-muscle myosin 2 on its intracellular diffusion
Horváth, Ádám I., Gyimesi, Máté, Várkuti, Boglárka H., Képiró, Miklós, Szegvári, Gábor, Lőrincz, István, Hegyi, György, Kovács, Mihály, Málnási-Csizmadia, András
Published in Scientific reports (07.08.2020)
Published in Scientific reports (07.08.2020)
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Application of neural-network-based deep-learning analysis to reveal changes of the movement parameters in rat neuromuscular disorder models
Winternitz, Mate, Gyimesi, Mate, Horvath, Adam I., Penzes, Mate, Malnasi-Csizmadia, Andras
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
The role of NM2 rearrangement during cytokinesis
Horvath, Adam I., Gyimesi, Mate, Kepiro, Miklos, Varkuti, Boglarka, Malnasi-Csizmadia, Andras
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Passive and active mechanical properties of titin studied in intact frog muscle fibers upon inhibition of myosin motors by para-nitro-blebbistatin
Squarci, Caterina, Bianco, Pasquale, Reconditi, Massimo, Pertici, Irene, Caremani, Marco, Narayanan, Theyencheri, Horvath, Adam I., Malnasi-Csizmadia, Andras, Linari, Marco, Lombardi, Vincenzo, Piazzesi, Gabriella
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
The New-Generation Muscle Relaxant MPH-220 Dissolves Spasticity in Muscles After Cns Injury - a Promising Drug to Address Post-Stroke Spasticity
Gyimesi, Mate, Horvath, Adam I., Túrós, Demeter, Hegyi, Gyorgy, Suthar, Sharad K., Kovacs, Mihaly, Malnasi-Csizmadia, Andras
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
First-in-class drug candidate (MPH-220) efficiently improves spastic gait disorders by selective inhibition of fast skeletal muscle myosin-2
Gyimesi, Mate, Horvath, Adam I., Turos, Demeter, Kumar Suthar, Sharad, Penzes, Mate, Canon, Louise, Kikuti, Carlos, Ruppel, Kathleen, Trivedi, Darshan V., Spudich, James A., Rauscher, Anna Á., Kovacs, Mihaly, Komoly, Samuel, Houdusse, Anne M., Malnasi-Csizmadia, Andras
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness
Gyimesi, Máté, Horváth, Ádám I., Túrós, Demeter, Suthar, Sharad Kumar, Pénzes, Máté, Kurdi, Csilla, Canon, Louise, Kikuti, Carlos, Ruppel, Kathleen M., Trivedi, Darshan V., Spudich, James A., Lőrincz, István, Rauscher, Anna Á., Kovács, Mihály, Pál, Endre, Komoly, Sámuel, Houdusse, Anne, Málnási-Csizmadia, András
Published in Cell (15.10.2020)
Published in Cell (15.10.2020)
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Interaction of SZV 1287, a novel oxime analgesic drug candidate, and its metabolites with serum albumin
Fliszár-Nyúl, Eszter, Faisal, Zelma, Mohos, Violetta, Derdák, Diána, Lemli, Beáta, Kálai, Tamás, Sár, Cecília, Zsidó, Balázs Z., Hetényi, Csaba, Horváth, Ádám I., Helyes, Zsuzsanna, Deme, Ruth, Bogdán, Dóra, Czompa, Andrea, Mátyus, Péter, Poór, Miklós
Published in Journal of molecular liquids (01.07.2021)
Published in Journal of molecular liquids (01.07.2021)
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Molecular Tattoo: Subcellular Confinement of Drug Effects In Vivo with Two-Photon Microscopy
Várkuti, Boglárka, Képiró, Miklós, Rauscher, Anna Á., Végner, László, Zsigmond, Áron, Imrich, Vanda, Ráti, Szilvia, Horváth, Ádám I., Varga, Máté, Kellermayer, Miklós S., Andras, Malnasi-Csizmadia
Published in Biophysical journal (03.02.2017)
Published in Biophysical journal (03.02.2017)
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Journal Article
Highly Soluble, Non-Phototoxic, Non-Fluorescent, Photostable Blebbistatin Derivatives
Rauscher, Anna Á., Kumar, Sharad, Várkuti, Boglárka H., Képiró, Miklós, Horváth, Ádám I., Végner, László, Hegyi, György, Borhegyi, Zsolt, Varga, Máté, Lenkei, Zsolt, Malnasi-Csizmadia, Andras
Published in Biophysical journal (03.02.2017)
Published in Biophysical journal (03.02.2017)
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Journal Article
미오신 2 이소형을 선택적으로 억제하는 약제학적으로 효과적인 화합물
KUMAR SUTHAR SHARAD, VEGNER LASZLO, HARI PETER, PENZES MATE, SZONYEGI ZOLTAN, LORINCZ ISTVAN, MALNASI CSIZMADIA ANDRAS, KOVACS MIHALY, HORVATH ADAM ISTVAN, GYIMESI MATE, REPASI JOZSEF, SIMON ZOLTAN, SZABO ANDRAS, BATORI SANDOR, HORVATH VAJK
Year of Publication 27.01.2021
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Year of Publication 27.01.2021
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