In vitro self-replication and multicistronic expression of large synthetic genomes
Libicher, K., Hornberger, R., Heymann, M., Mutschler, H.
Published in Nature communications (14.02.2020)
Published in Nature communications (14.02.2020)
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Journal Article
Protein degraders enter the clinic — a new approach to cancer therapy
Chirnomas, Deborah, Hornberger, Keith R., Crews, Craig M.
Published in Nature reviews. Clinical oncology (01.04.2023)
Published in Nature reviews. Clinical oncology (01.04.2023)
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Journal Article
RGM is a repulsive guidance molecule for retinal axons
Mueller, Bernhard K, Monnier, Philippe P, Sierra, Ana, Macchi, Paolo, Deitinghoff, Lutz, Andersen, Jens S, Mann, Matthias, Flad, Manuela, Hornberger, Martin R, Stahl, Bernd, Bonhoeffer, Friedrich
Published in Nature (London) (26.09.2002)
Published in Nature (London) (26.09.2002)
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Journal Article
446: A gain of function by the cancer-associated FGFR4 c.1162G>A (p.Gly388Arg) variant
Ulaganathan, V.K, Sperl, B, Mayr, T, Hornberger, R, Rapp, U.R, Ullrich, A
Published in European journal of cancer (1990) (01.07.2014)
Published in European journal of cancer (1990) (01.07.2014)
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Journal Article
Modulation of EphA Receptor Function by Coexpressed EphrinA Ligands on Retinal Ganglion Cell Axons
Hornberger, Martin R., Dütting, Dieter, Ciossek, Thomas, Yamada, Tomoko, Handwerker, Claudia, Lang, Susanne, Weth, Franco, Huf, Julita, Weßel, Ralf, Logan, Cairine, Tanaka, Hideaki, Drescher, Uwe
Published in Neuron (Cambridge, Mass.) (01.04.1999)
Published in Neuron (Cambridge, Mass.) (01.04.1999)
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Journal Article
Total Synthesis of Leucascandrolide A
Hornberger, Keith R, Hamblett, Christopher L, Leighton, James L
Published in Journal of the American Chemical Society (27.12.2000)
Published in Journal of the American Chemical Society (27.12.2000)
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Journal Article
Evidence for Allosteric Interactions of Antagonist Binding to the Smoothened Receptor
Rominger, Cynthia M, Bee, Wei-Lin Tiger, Copeland, Robert A, Davenport, Elizabeth A, Gilmartin, Aidan, Gontarek, Richard, Hornberger, Keith R, Kallal, Lorena A, Lai, Zhihong, Lawrie, Kenneth, Lu, Quinn, McMillan, Lynette, Truong, Maggie, Tummino, Peter J, Turunen, Brandon, Will, Matthew, Zuercher, William J, Rominger, David H
Published in The Journal of pharmacology and experimental therapeutics (01.06.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2009)
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Journal Article
Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors
Waterson, Alex G., Petrov, Kimberly G., Hornberger, Keith R., Hubbard, Robert D., Sammond, Douglas M., Smith, Stephon C., Dickson, Hamilton D., Caferro, Thomas R., Hinkle, Kevin W., Stevens, Kirk L., Dickerson, Scott H., Rusnak, David W., Spehar, Glenn M., Wood, Edgar R., Griffin, Robert J., Uehling, David E.
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
Published in Bioorganic & medicinal chemistry letters (01.03.2009)
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Journal Article
Dual EGFR/ErbB-2 inhibitors from novel pyrrolidinyl-acetylenic thieno[3,2- d]pyrimidines
Hubbard, Robert D., Dickerson, Scott H., Emerson, Holly K., Griffin, Robert J., Reno, Michael J., Hornberger, Keith R., Rusnak, David W., Wood, Edgar R., Uehling, David E., Waterson, Alex G.
Published in Bioorganic & medicinal chemistry (01.11.2008)
Published in Bioorganic & medicinal chemistry (01.11.2008)
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Journal Article
Association between parental education level & outcomes for children with long-term ventilator dependence: Communication behaviors as moderating variables
Hornberger, Sydney R., Zhang, Yin, Zhang, Nanhua, Giambra, Barbara K.
Published in Journal of pediatric nursing (01.03.2024)
Published in Journal of pediatric nursing (01.03.2024)
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Journal Article
Shared and distinct functions of RAGS and ELF-1 in guiding retinal axons
Monschau, Bruno, Kremoser, Claus, Ohta, Kunimasa, Tanaka, Hideaki, Kaneko, Tomomi, Yamada, Tomoko, Handwerker, Claudia, Hornberger, Martin R., Löschinger, Jürgen, Pasquale, Elena B., Siever, Doyle A., Verderame, Michael F., Müller, Bernhard K., Bonhoeffer, Friedrich, Drescher, Uwe
Published in The EMBO journal (17.03.1997)
Published in The EMBO journal (17.03.1997)
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Journal Article
Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B‑Raf-Driven Tumors
Rheault, Tara R., Stellwagen, John C., Adjabeng, George M., Hornberger, Keith R., Petrov, Kimberly G., Waterson, Alex G., Dickerson, Scott H., Mook, Robert A., Laquerre, Sylvie G., King, Alastair J., Rossanese, Olivia W., Arnone, Marc R., Smitheman, Kimberly N., Kane-Carson, Laurie S., Han, Chao, Moorthy, Ganesh S., Moss, Katherine G., Uehling, David E.
Published in ACS medicinal chemistry letters (14.03.2013)
Published in ACS medicinal chemistry letters (14.03.2013)
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Journal Article
Room-Temperature Pd-Catalyzed Amidation of Aryl Bromides Using tert-Butyl Carbamate
Bhagwanth, Swapna, Waterson, Alex G, Adjabeng, George M, Hornberger, Keith R
Published in Journal of organic chemistry (19.06.2009)
Published in Journal of organic chemistry (19.06.2009)
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Journal Article
Dihydrobenzisoxazole-4-one compounds are novel selective inhibitors of aldosterone synthase (CYP11B2) with in vivo activity
Meyers, Kenneth, Cogan, Derek A., Burke, Jennifer, Arenas, Raquel, Balestra, Michael, Brown, Nicholas F., Chen, Zhidong, Cerny, Matthew A., Clifford, Holly E., Colombo, Federico, Fader, Lee, Frederick, Kosea S., Guo, Xin, Goldberg, Daniel, Hornberger, Keith R., Kugler, Stanley, Lord, John, Marshall, Daniel R., Moss, Neil, Parmentier, Jean-Huges, Richman, Jeremy R., Schmenk, Jennifer, Weldon, Steven M., Yu, Maolin, Zhang, Michael
Published in Bioorganic & medicinal chemistry letters (01.03.2018)
Published in Bioorganic & medicinal chemistry letters (01.03.2018)
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Journal Article
Yb(OTf)3-Catalyzed Oxymercuration of Homoallylic Alcohol-Derived Hemiacetals and Hemiketals
Dreher, Spencer D, Hornberger, Keith R, Sarraf, Stella T, Leighton, James L
Published in Organic letters (05.10.2000)
Published in Organic letters (05.10.2000)
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Journal Article
Discovery of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1: Optimization of kinase selectivity and pharmacokinetics
Hornberger, Keith R., Chen, Xin, Crew, Andrew P., Kleinberg, Andrew, Ma, Lifu, Mulvihill, Mark J., Wang, Jing, Wilde, Victoria L., Albertella, Mark, Bittner, Mark, Cooke, Andrew, Kadhim, Salam, Kahler, Jennifer, Maresca, Paul, May, Earl, Meyn, Peter, Romashko, Darlene, Tokar, Brianna, Turton, Roy
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
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Journal Article
Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1
Hornberger, Keith R., Berger, Dan M., Crew, Andrew P., Dong, Hanqing, Kleinberg, Andrew, Li, An-Hu, Medeiros, Matthew R., Mulvihill, Mark J., Siu, Kam, Tarrant, James, Wang, Jing, Weng, Felix, Wilde, Victoria L., Albertella, Mark, Bittner, Mark, Cooke, Andrew, Gray, Michael J., Maresca, Paul, May, Earl, Meyn, Peter, Peick, William, Romashko, Darlene, Tanowitz, Michael, Tokar, Brianna
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
Published in Bioorganic & medicinal chemistry letters (15.08.2013)
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Journal Article
Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding
EMMITTE, Kyle A, ADJEBANG, George M, JACKSON, Jeffrey R, KUNTZ, Kevin W, LANSING, Timothy J, MOOK, Robert A, NAILOR, Kristen E, POBANZ, Mark A, SMITH, Stephon C, SUNG, Chiu-Mei, CHEUNG, Mui, WEBB ANDREWS, C, BADIANG ALBERTI, Jennifer G, BAMBAL, Ramesh, CHAMBERLAIN, Stanley D, DAVIS-WARD, Ronda G, DICKSON, Hamilton D, HASSLER, Daniel F, HORNBERGER, Keith R
Published in Bioorganic & medicinal chemistry letters (15.03.2009)
Published in Bioorganic & medicinal chemistry letters (15.03.2009)
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Journal Article