A novel class of antagonists for metabotropic glutamate receptors, 7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylates
Annoura, Hirokazu, Fukunaga, Atsuko, Uesugi, Mayumi, Tatsuoka, Toshio, Horikawa, Yoshiko
Published in Bioorganic & medicinal chemistry letters (09.04.1996)
Published in Bioorganic & medicinal chemistry letters (09.04.1996)
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Pharmacological Properties of the Potent Epileptogenic Amino Acid Dysiherbaine, a Novel Glutamate Receptor Agonist Isolated from the Marine Sponge Dysidea herbacea
Sakai, R, Swanson, G T, Shimamoto, K, Green, T, Contractor, A, Ghetti, A, Tamura-Horikawa, Y, Oiwa, C, Kamiya, H
Published in The Journal of pharmacology and experimental therapeutics (01.02.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.02.2001)
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The Synthesis and Antilipidperoxidation Activity of 4, 4-Diarylbutylamines and 4, 4-Diarylbutanamides
MIYANO, Seiji, TATSUOKA, Toshio, SUZUKI, Kenji, IMAO, Kayoko, SATOH, Fumio, ISHIHARA, Tkafumi, HIROTSU, Ichiro, KIHARA, Tetsuro, HATTA, Mizuho, HORIKAWA, Yoshiko, SUMOTO, Kunihiro
Published in Chemical & pharmaceutical bulletin (1990)
Published in Chemical & pharmaceutical bulletin (1990)
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Cerebral protective agents. Preparation and Pharmacological Evaluation of 4-(1,4-Benzoquinon-2-yl)-4-phenylbutanamides as Potential Cerebral Protective Agents
TATSUOKA, Toshio, SUZUKI, Kenji, IMAO, Kayoko, SATOH, Fumio, ISIHARA, Takehumi, HIROTU, Ichiro, KIHARA, Tetsuro, HATTA, Mizuho, HORIKAWA, Yoshiko, SUMOTO, Kunihiro, MIYANO, Seiji
Published in Chemical & pharmaceutical bulletin (1992)
Published in Chemical & pharmaceutical bulletin (1992)
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Discovery of (2S)-1-(4-Amino-2,3,5- trimethylphenoxy)-3-{4-[4-(4- fluorobenzyl)phenyl]-1-piperazinyl}-2- propanol Dimethanesulfonate (SUN N8075): A Dual Na+ and Ca2+ Channel Blocker with Antioxidant Activity
Annoura, Hirokazu, Nakanishi, Kyoko, Toba, Tetsuya, Takemoto, Naohiro, Imajo, Seiichi, Miyajima, Atsuko, Tamura-Horikawa, Yoshiko, Tamura, Shigeki
Published in Journal of medicinal chemistry (07.09.2000)
Published in Journal of medicinal chemistry (07.09.2000)
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Synthesis and biological evaluation of new 4-arylpiperidines and 4-aryl-4-piperidinols: dual Na(+) and Ca(2+) channel blockers with reduced affinity for dopamine D(2) receptors
Annoura, Hirokazu, Nakanishi, Kyoko, Uesugi, Mayumi, Fukunaga, Atsuko, Imajo, Seiichi, Miyajima, Atsuko, Tamura-Horikawa, Yoshiko, Tamura, Shigeki
Published in Bioorganic & medicinal chemistry (01.02.2002)
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Published in Bioorganic & medicinal chemistry (01.02.2002)
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Synthesis and biological evaluation of new 4-arylpiperidines and 4-aryl-4-piperidinols: Dual Na+ and Ca2+ channel blockers with reduced affinity for dopamine D2 receptors
ANNOURA, Hirokazu, NAKANISHI, Kyoko, UESUGI, Mayumi, FUKUNAGA, Atsuko, IMAJO, Seiichi, MIYAJIMA, Atsuko, TAMURA-HORIKAWA, Yoshiko, TAMURA, Shigeki
Published in Bioorganic & medicinal chemistry (01.02.2002)
Published in Bioorganic & medicinal chemistry (01.02.2002)
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Synthesis and biological evaluation of new 4-arylpiperidines and 4-aryl-4-piperidinols: dual Na + and Ca 2+ channel blockers with reduced affinity for dopamine D 2 receptors
Annoura, Hirokazu, Nakanishi, Kyoko, Uesugi, Mayumi, Fukunaga, Atsuko, Imajo, Seiichi, Miyajima, Atsuko, Tamura-Horikawa, Yoshiko, Tamura, Shigeki
Published in Bioorganic & medicinal chemistry (2002)
Published in Bioorganic & medicinal chemistry (2002)
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CYCLOPROPACHROMENECARBOXYLATE DERIVATIVES
HORIKAWA, YOSHIKO, TATSUOKA, TOSHIO, ANNOURA, HIROKAZU, FUKUNAGA, ATSUKO
Year of Publication 02.05.1996
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Year of Publication 02.05.1996
Patent
Discovery of (2 S )-1-(4-Amino-2,3,5- trimethylphenoxy)-3-{4-[4-(4- fluorobenzyl)phenyl]-1-piperazinyl}-2- propanol Dimethanesulfonate (SUN N8075): A Dual Na + and Ca 2+ Channel Blocker with Antioxidant Activity
Annoura, Hirokazu, Nakanishi, Kyoko, Toba, Tetsuya, Takemoto, Naohiro, Imajo, Seiichi, Miyajima, Atsuko, Tamura-Horikawa, Yoshiko, Tamura, Shigeki
Published in Journal of medicinal chemistry (01.09.2000)
Published in Journal of medicinal chemistry (01.09.2000)
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A novel class of Na + and Ca 2+ channel dual blockers with highly potent anti-ischemic effects
Annoura, Hirokazu, Nakanishi, Kyoko, Uesugi, Mayumi, Fukunaga, Atsuko, Miyajima, Atsuko, Tamura-Horikawa, Yoshiko, Tamura, Shigeki
Published in Bioorganic & medicinal chemistry letters (1999)
Published in Bioorganic & medicinal chemistry letters (1999)
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Activation of mGluR2/mGluR3 metabotropic glutamate receptor induces reversible suppression of spontaneous [Ca 2+] i oscillations in cultured rat cerebral cortical neurons
Horikawa, Yoshiko, Tamura, Shigeki, Inomata, Norio
Published in Neuroscience research. Supplement (1994)
Published in Neuroscience research. Supplement (1994)
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