Targeting of CD44 eradicates human acute myeloid leukemic stem cells
Dick, John E, Jin, Liqing, Hope, Kristin J, Zhai, Qiongli, Smadja-Joffe, Florence
Published in Nature medicine (01.10.2006)
Published in Nature medicine (01.10.2006)
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The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors
Liu, Lina, Vujovic, Ana, Deshpande, Nandan P., Sathe, Shashank, Anande, Govardhan, Chen, He Tian Tony, Xu, Joshua, Minden, Mark D., Yeo, Gene W., Unnikrishnan, Ashwin, Hope, Kristin J., Lu, Yu
Published in Nature communications (04.07.2022)
Published in Nature communications (04.07.2022)
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An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity
Hope, Kristin J., Cellot, Sonia, Ting, Stephen B., MacRae, Tara, Mayotte, Nadine, Iscove, Norman N., Sauvageau, Guy
Published in Cell stem cell (02.07.2010)
Published in Cell stem cell (02.07.2010)
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RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity
Cellot, Sonia, Hope, Kristin J., Chagraoui, Jalila, Sauvageau, Martin, Deneault, Éric, MacRae, Tara, Mayotte, Nadine, Wilhelm, Brian T., Landry, Josette R., Ting, Stephen B., Krosl, Jana, Humphries, Keith, Thompson, Alexander, Sauvageau, Guy
Published in Blood (29.08.2013)
Published in Blood (29.08.2013)
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RNA binding protein‐directed control of leukemic stem cell evolution and function
Joshi, Pratik, Keyvani Chahi, Ava, Liu, Lina, Moreira, Steven, Vujovic, Ana, Hope, Kristin J.
Published in HemaSphere (01.08.2024)
Published in HemaSphere (01.08.2024)
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DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants
Kwan, Vickie, Meka, Durga Praveen, White, Sean H., Hung, Claudia L., Holzapfel, Nicholas T., Walker, Susan, Murtaza, Nadeem, Unda, Brianna K., Schwanke, Birgit, Yuen, Ryan K.C., Habing, Kendra, Milsom, Chloe, Hope, Kristin J., Truant, Ray, Scherer, Stephen W., Calderon de Anda, Froylan, Singh, Karun K.
Published in Cell reports (Cambridge) (08.11.2016)
Published in Cell reports (Cambridge) (08.11.2016)
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Producing megakaryocytes from a human peripheral blood source
Ivetic, Nikola, Nazi, Ishac, Karim, Nadia, Clare, Rumi, Smith, James W., Moore, Jane C., Hope, Kristin J., Kelton, John G., Arnold, Donald M.
Published in Transfusion (Philadelphia, Pa.) (01.05.2016)
Published in Transfusion (Philadelphia, Pa.) (01.05.2016)
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Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia
Zhou, Xinyue, Zhang, Lixia, Aryal, Sajesan, Veasey, Virginia, Tajik, Amanda, Restelli, Cecilia, Moreira, Steven, Zhang, Pengcheng, Zhang, Yanfeng, Hope, Kristin J., Zhou, Yang, Cheng, Changde, Bhatia, Ravi, Lu, Rui
Published in Blood (07.11.2024)
Published in Blood (07.11.2024)
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Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells
Rentas, Stefan, Holzapfel, Nicholas T., Belew, Muluken S., Pratt, Gabriel A., Voisin, Veronique, Wilhelm, Brian T., Bader, Gary D., Yeo, Gene W., Hope, Kristin J.
Published in Nature (London) (28.04.2016)
Published in Nature (London) (28.04.2016)
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Journal Article
Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance
Ly, Michelle, Rentas, Stefan, Vujovic, Ana, Wong, Nicholas, Moreira, Steven, Xu, Joshua, Holzapfel, Nicholas, Bhatia, Sonam, Tran, Damian, Minden, Mark D, Draper, Jonathan S, Hope, Kristin J
Published in Cancer research (Chicago, Ill.) (15.11.2019)
Published in Cancer research (Chicago, Ill.) (15.11.2019)
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OTUD7A Regulates Neurodevelopmental Phenotypes in the 15q13.3 Microdeletion Syndrome
Uddin, Mohammed, Unda, Brianna K., Kwan, Vickie, Holzapfel, Nicholas T., White, Sean H., Chalil, Leon, Woodbury-Smith, Marc, Ho, Karen S., Harward, Erin, Murtaza, Nadeem, Dave, Biren, Pellecchia, Giovanna, D’Abate, Lia, Nalpathamkalam, Thomas, Lamoureux, Sylvia, Wei, John, Speevak, Marsha, Stavropoulos, James, Hope, Kristin J., Doble, Brad W., Nielsen, Jacob, Wassman, E. Robert, Scherer, Stephen W., Singh, Karun K.
Published in American journal of human genetics (01.02.2018)
Published in American journal of human genetics (01.02.2018)
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PLAG1 dampens protein synthesis to promote human hematopoietic stem cell self-renewal
Keyvani Chahi, Ava, Belew, Muluken S., Xu, Joshua, Chen, He Tian Tony, Rentas, Stefan, Voisin, Veronique, Krivdova, Gabriela, Lechman, Eric, Marhon, Sajid A., De Carvalho, Daniel D., Dick, John E., Bader, Gary D., Hope, Kristin J.
Published in Blood (01.09.2022)
Published in Blood (01.09.2022)
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Journal Article
A role for GPx3 in activity of normal and leukemia stem cells
Herault, Olivier, Hope, Kristin J, Deneault, Eric, Mayotte, Nadine, Chagraoui, Jalila, Wilhelm, Brian T, Cellot, Sonia, Sauvageau, Martin, Andrade-Navarro, Miguel A, Hébert, Josée, Sauvageau, Guy
Published in The Journal of experimental medicine (07.05.2012)
Published in The Journal of experimental medicine (07.05.2012)
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Spermidine metabolism regulates leukemia stem and progenitor cell function through KAT7 expression in patient-derived mouse models
Rondeau, Vincent, Berman, Jacob M, Ling, Tianyi, O'Brien, Cristiana, Culp-Hill, Rachel, Reisz, Julie A, Wunderlich, Mark, Chueh, Yun, Jiménez-Camacho, Karina E, Sexton, Christina, Carter, Katharine M, Stillwell, Cody, St-Germain, Jonathan, Yendi, Duhan, Gupta, Aarushi, Shi, Mary, Bourdine, Aleksandra, Paralkar, Vikram R, Jahangiri, Soheil, Hope, Kristin J, Tikhonova, Anastasia N, Arruda, Andrea, Minden, Mark D, Raught, Brian, D'Alessandro, Angelo, Jones, Courtney L
Published in Science translational medicine (25.09.2024)
Published in Science translational medicine (25.09.2024)
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