Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference
Hop, Paul J, Luijk, René, Daxinger, Lucia, van Iterson, Maarten, Dekkers, Koen F, Jansen, Rick, van Meurs, Joyce B J, 't Hoen, Peter A C, Ikram, M Arfan, van Greevenbroek, Marleen M J, Boomsma, Dorret I, Slagboom, P Eline, Veldink, Jan H, van Zwet, Erik W, Heijmans, Bastiaan T
Published in Genome Biology (28.08.2020)
Published in Genome Biology (28.08.2020)
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Rare and common genetic determinants of mitochondrial function determine severity but not risk of amyotrophic lateral sclerosis
Harvey, Calum, Weinreich, Marcel, Lee, James A.K., Shaw, Allan C., Ferraiuolo, Laura, Mortiboys, Heather, Zhang, Sai, Hop, Paul J., Zwamborn, Ramona A.J., van Eijk, Kristel, Julian, Thomas H., Moll, Tobias, Iacoangeli, Alfredo, Al Khleifat, Ahmad, Quinn, John P., Pfaff, Abigail L., Kõks, Sulev, Poulton, Joanna, Battle, Stephanie L., Arking, Dan E., Snyder, Michael P., Veldink, Jan H., Kenna, Kevin P., Shaw, Pamela J., Cooper-Knock, Johnathan
Published in Heliyon (15.02.2024)
Published in Heliyon (15.02.2024)
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Systematic rare variant analyses identify RAB32 as a susceptibility gene for familial Parkinson’s disease
Hop, Paul J., Lai, Dongbing, Keagle, Pamela J., Baron, Desiree M., Kenna, Brendan J., Kooyman, Maarten, Shankaracharya, Halter, Cheryl, Straniero, Letizia, Asselta, Rosanna, Bonvegna, Salvatore, Soto-Beasley, Alexandra I., Wszolek, Zbigniew K., Uitti, Ryan J., Isaias, Ioannis Ugo, Pezzoli, Gianni, Ticozzi, Nicola, Ross, Owen A., Veldink, Jan H., Foroud, Tatiana M., Kenna, Kevin P., Landers, John E.
Published in Nature genetics (01.07.2024)
Published in Nature genetics (01.07.2024)
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Journal Article
Whole genome sequencing analysis reveals post-zygotic mutation variability in monozygotic twins discordant for amyotrophic lateral sclerosis
Tazelaar, Gijs H.P., Hop, Paul J., Seelen, Meinie, van Vugt, Joke J.F.A., van Rheenen, Wouter, Kool, Lindy, van Eijk, Kristel R., Gijzen, Marleen, Dooijes, Dennis, Moisse, Matthieu, Calvo, Andrea, Moglia, Cristina, Brunetti, Maura, Canosa, Antonio, Nordin, Angelica, Pardina, Jesus S. Mora, Ravits, John, Al-Chalabi, Ammar, Chio, Adriano, McLaughlin, Russell L., Hardiman, Orla, Van Damme, Philip, de Carvalho, Mamede, Neuwirth, Christoph, Weber, Markus, Andersen, Peter M, van den Berg, Leonard H., Veldink, Jan H., van Es, Michael A.
Published in Neurobiology of aging (01.02.2023)
Published in Neurobiology of aging (01.02.2023)
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Journal Article
Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis
Nabais, Marta F., Lin, Tian, Benyamin, Beben, Williams, Kelly L., Garton, Fleur C., Vinkhuyzen, Anna A. E., Zhang, Futao, Vallerga, Costanza L., Restuadi, Restuadi, Freydenzon, Anna, Zwamborn, Ramona A. J., Hop, Paul J., Robinson, Matthew R., Gratten, Jacob, Visscher, Peter M., Hannon, Eilis, Mill, Jonathan, Brown, Matthew A., Laing, Nigel G., Mather, Karen A., Sachdev, Perminder S., Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Henders, Anjali K., Needham, Merrilee, Veldink, Jan H., Mathers, Susan, Nicholson, Garth, Rowe, Dominic B., Henderson, Robert D., McCombe, Pamela A., Pamphlett, Roger, Yang, Jian, Blair, Ian P., McRae, Allan F., Wray, Naomi R.
Published in Npj genomic medicine (27.02.2020)
Published in Npj genomic medicine (27.02.2020)
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Journal Article
Cross-reactive probes on Illumina DNA methylation arrays: a large study on ALS shows that a cautionary approach is warranted in interpreting epigenome-wide association studies
Hop, Paul J, Zwamborn, Ramona A J, Hannon, Eilis J, Dekker, Annelot M, van Eijk, Kristel R, Walker, Emma M, Iacoangeli, Alfredo, Jones, Ashley R, Shatunov, Aleksey, Khleifat, Ahmad Al, Opie-Martin, Sarah, Shaw, Christopher E, Morrison, Karen E, Shaw, Pamela J, McLaughlin, Russell L, Hardiman, Orla, Al-Chalabi, Ammar, Van Den Berg, Leonard H, Mill, Jonathan, Veldink, Jan H
Published in NAR genomics and bioinformatics (01.12.2020)
Published in NAR genomics and bioinformatics (01.12.2020)
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Journal Article
Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis
Nabais, Marta F, Lin, Tian, Benyamin, Beben, Williams, Kelly L, Garton, Fleur C, Vinkhuyzen, Anna A E, Zhang, Futao, Vallerga, Costanza L, Restuadi, Restuadi, Freydenzon, Anna, Zwamborn, Ramona A J, Hop, Paul J, Robinson, Matthew R, Gratten, Jacob, Visscher, Peter M, Hannon, Eilis, Mill, Jonathan, Brown, Matthew A, Laing, Nigel G, Mather, Karen A, Sachdev, Perminder S, Ngo, Shyuan T, Steyn, Frederik J, Wallace, Leanne, Henders, Anjali K, Needham, Merrilee, Veldink, Jan H, Mathers, Susan, Nicholson, Garth, Rowe, Dominic B, Henderson, Robert D, McCombe, Pamela A, Pamphlett, Roger, Yang, Jian, Blair, Ian P, McRae, Allan F, Wray, Naomi R
Published in Npj genomic medicine (27.02.2020)
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Published in Npj genomic medicine (27.02.2020)
Journal Article
Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference
Hop, Paul J, Luijk, René, Daxinger, Lucia, Maarten Van Iterson, Dekkers, Koen F, Jansen, Rick, Consortium, Bios, Van Meurs, Joyce Bj, Peter Ac 't Hoen, Ikram, M Arfan, Marleen Mj Van Greevenbroek, Boomsma, Dorret I, P Eline Slagboom, Veldink, Jan H, Van Zwet, Erik W, Heijmans, Bastiaan T
Published in bioRxiv (30.10.2019)
Published in bioRxiv (30.10.2019)
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