Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients
Claushuis, Theodora A.M., van Vught, Lonneke A., Scicluna, Brendon P., Wiewel, Maryse A., Klein Klouwenberg, Peter M.C., Hoogendijk, Arie J., Ong, David S.Y., Cremer, Olaf L., Horn, Janneke, Franitza, Marek, Toliat, Mohammad R., Nürnberg, Peter, Zwinderman, Aeilko H., Bonten, Marc J., Schultz, Marcus J., van der Poll, Tom
Published in Blood (16.06.2016)
Published in Blood (16.06.2016)
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Dynamic Transcriptome-Proteome Correlation Networks Reveal Human Myeloid Differentiation and Neutrophil-Specific Programming
Hoogendijk, Arie J., Pourfarzad, Farzin, Aarts, Cathelijn E.M., Tool, Anton T.J., Hiemstra, Ida H., Grassi, Luigi, Frontini, Mattia, Meijer, Alexander B., van den Biggelaar, Maartje, Kuijpers, Taco W.
Published in Cell reports (Cambridge) (19.11.2019)
Published in Cell reports (Cambridge) (19.11.2019)
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A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission
Scicluna, Brendon P, Klein Klouwenberg, Peter M C, van Vught, Lonneke A, Wiewel, Maryse A, Ong, David S Y, Zwinderman, Aeilko H, Franitza, Marek, Toliat, Mohammad R, Nürnberg, Peter, Hoogendijk, Arie J, Horn, Janneke, Cremer, Olaf L, Schultz, Marcus J, Bonten, Marc J, van der Poll, Tom
Published in American journal of respiratory and critical care medicine (01.10.2015)
Published in American journal of respiratory and critical care medicine (01.10.2015)
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Journal Article
Integrative phosphoproteomic analysis reveal hemostatic-endothelial signaling interplay
Groten, Stijn A, van den Eshof, Bart L, van Alphen, Floris P J, Meijer, Alexander B, van den Biggelaar, Maartje, Hoogendijk, Arie J
Published in Journal of thrombosis and haemostasis (21.10.2024)
Published in Journal of thrombosis and haemostasis (21.10.2024)
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Journal Article
Immune suppression is associated with enhanced systemic inflammatory, endothelial and procoagulant responses in critically ill patients
Brands, Xanthe, Uhel, Fabrice, van Vught, Lonneke A, Wiewel, Maryse A, Hoogendijk, Arie J, Lutter, René, Schultz, Marcus J, Scicluna, Brendon P, van der Poll, Tom
Published in PloS one (25.07.2022)
Published in PloS one (25.07.2022)
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Journal Article
The leukocyte non-coding RNA landscape in critically ill patients with sepsis
Scicluna, Brendon P, Uhel, Fabrice, van Vught, Lonneke A, Wiewel, Maryse A, Hoogendijk, Arie J, Baessman, Ingelore, Franitza, Marek, Nürnberg, Peter, Horn, Janneke, Cremer, Olaf L, Bonten, Marc J, Schultz, Marcus J, van der Poll, Tom
Published in eLife (11.12.2020)
Published in eLife (11.12.2020)
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Journal Article
Syntaxin 5 determines Weibel-Palade body size and Von Willebrand factor secretion by controlling Golgi architecture
Kat, Marije, Karampini, Ellie, Hoogendijk, Arie J, Bürgisser, Petra E, Mulder, Aat A, Van Alphen, Floris P J, Olins, Jenny, Geerts, Dirk, Van den Biggelaar, Maartje, Margadant, Coert, Voorberg, Jan, Bierings, Ruben
Published in Haematologica (Roma) (01.08.2022)
Published in Haematologica (Roma) (01.08.2022)
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Distinct protein patterns related to postnatal development in small for gestational age preterm infants
Smit, Eva R, Romijn, Michelle, Langerhorst, Pieter, van der Zwaan, Carmen, van der Staaij, Hilde, Rotteveel, Joost, van Kaam, Anton H, Fustolo-Gunnink, Suzanne F, Hoogendijk, Arie J, Onland, Wes, Finken, Martijn J J, van den Biggelaar, Maartje
Published in Pediatric research (16.08.2024)
Published in Pediatric research (16.08.2024)
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Journal Article
Admission Hyperglycemia in Critically Ill Sepsis Patients: Association With Outcome and Host Response
van Vught, Lonneke A, Wiewel, Maryse A, Klein Klouwenberg, Peter M C, Hoogendijk, Arie J, Scicluna, Brendon P, Ong, David S Y, Cremer, Olaf L, Horn, Janneke, Bonten, Marc M J, Schultz, Marcus J, van der Poll, Tom
Published in Critical care medicine (01.07.2016)
Published in Critical care medicine (01.07.2016)
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Journal Article
Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients
van Vught, Lonneke A, Scicluna, Brendon P, Wiewel, Maryse A, Hoogendijk, Arie J, Klein Klouwenberg, Peter M C, Franitza, Marek, Toliat, Mohammad R, Nürnberg, Peter, Cremer, Olaf L, Horn, Janneke, Schultz, Marcus J, Bonten, Marc M J, van der Poll, Tom
Published in American journal of respiratory and critical care medicine (01.12.2016)
Published in American journal of respiratory and critical care medicine (01.12.2016)
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Journal Article
Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes
van Amstel, Rombout B. E., Kennedy, Jason N., Scicluna, Brendon P., Bos, Lieuwe D. J., Peters-Sengers, Hessel, Butler, Joe M., Cano-Gamez, Eddie, Knight, Julian C., Vlaar, Alexander P. J., Cremer, Olaf L., Angus, Derek C., van der Poll, Tom, Seymour, Christopher W., van Vught, Lonneke A.
Published in Intensive care medicine (01.11.2023)
Published in Intensive care medicine (01.11.2023)
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Journal Article
Variant mapping using mass spectrometry–based proteotyping as a diagnostic tool in von Willebrand disease
Kreft, Iris C., van Duijl, Tirsa T., van Kwawegen, Calvin, Atiq, Ferdows, Phan, Winny, Schuller, Margo B.P., Boon-Spijker, Mariëtte, van der Zwaan, Carmen, Meijer, Alexander B., Hoogendijk, Arie J., Bierings, Ruben, Eikenboom, Jeroen C.J., Leebeek, Frank W.G., van den Biggelaar, Maartje
Published in Journal of thrombosis and haemostasis (01.07.2024)
Published in Journal of thrombosis and haemostasis (01.07.2024)
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Journal Article
Source-specific host response and outcomes in critically ill patients with sepsis: a prospective cohort study
Peters-Sengers, Hessel, Butler, Joe M., Uhel, Fabrice, Schultz, Marcus J., Bonten, Marc J., Cremer, Olaf L., Scicluna, Brendon P., van Vught, Lonneke A., van der Poll, Tom
Published in Intensive care medicine (01.01.2022)
Published in Intensive care medicine (01.01.2022)
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Journal Article
The circular RNA landscape in specific peripheral blood mononuclear cells of critically ill patients with sepsis
Khan, Hina N, Brands, Xanthe, Aufiero, Simona, Hoogendijk, Arie J, Klarenbeek, Augustijn M, van Engelen, Tjitske S R, Haak, Bastiaan W, van Vught, Lonneke A, Horn, Janneke, Schultz, Marcus J, Zwinderman, Aeilko H, van der Poll, Tom, Scicluna, Brendon P
Published in Critical care (London, England) (13.07.2020)
Published in Critical care (London, England) (13.07.2020)
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Journal Article
The Host Response in Patients with Sepsis Developing Intensive Care Unit-acquired Secondary Infections
van Vught, Lonneke A, Wiewel, Maryse A, Hoogendijk, Arie J, Frencken, Jos F, Scicluna, Brendon P, Klein Klouwenberg, Peter M C, Zwinderman, Aeilko H, Lutter, Rene, Horn, Janneke, Schultz, Marcus J, Bonten, Marc M J, Cremer, Olaf L, van der Poll, Tom
Published in American journal of respiratory and critical care medicine (15.08.2017)
Published in American journal of respiratory and critical care medicine (15.08.2017)
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Journal Article
Proteomic profiling of neutrophils and plasma in community-acquired pneumonia reveals crucial proteins in diverse biological pathways linked to clinical outcome
Michels, Erik H. A., Chouchane, Osoul, de Brabander, Justin, de Vos, Alex F., Faber, Daniël R., Douma, Renée A., Smit, Eva R., Wiersinga, W. Joost, Biggelaar, Maartje van den, Poll, Tom van der, Hoogendijk, Arie J.
Published in Frontiers in immunology (18.10.2024)
Published in Frontiers in immunology (18.10.2024)
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Journal Article
Paradigm of Biased PAR1 (Protease-Activated Receptor-1) Activation and Inhibition in Endothelial Cells Dissected by Phosphoproteomics
van den Eshof, Bart L, Hoogendijk, Arie J, Simpson, Pelle J, van Alphen, Floris P J, Zanivan, Sara, Mertens, Koen, Meijer, Alexander B, van den Biggelaar, Maartje
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2017)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2017)
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Journal Article
Flow-induced Reorganization of Laminin-integrin Networks Within the Endothelial Basement Membrane Uncovered by Proteomics
Béguin, Eelke P., Janssen, Esmée F.J., Hoogenboezem, Mark, Meijer, Alexander B., Hoogendijk, Arie J., van den Biggelaar, Maartje
Published in Molecular & cellular proteomics (01.07.2020)
Published in Molecular & cellular proteomics (01.07.2020)
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Journal Article
Proteomic landscapes of inherited platelet disorders with different etiologies
Kreft, Iris C., Huisman, Elise J., Cnossen, Marjon H., van Alphen, Floris P.J., van der Zwaan, Carmen, van Leeuwen, Karin, van Spaendonk, Rosalina, Porcelijn, Leendert, Veen, Caroline S.B., van den Biggelaar, Maartje, de Haas, Masja, Meijer, Alexander B., Hoogendijk, Arie J.
Published in Journal of thrombosis and haemostasis (01.02.2023)
Published in Journal of thrombosis and haemostasis (01.02.2023)
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Journal Article
Expression of intra- and extracellular granzymes in patients with typhoid fever
de Jong, Hanna K, Garcia-Laorden, Maria Isabel, Hoogendijk, Arie J, Parry, Christopher M, Maude, Rapeephan R, Dondorp, Arjen M, Faiz, Mohammed Abul, van der Poll, Tom, Wiersinga, Willem Joost
Published in PLoS neglected tropical diseases (27.07.2017)
Published in PLoS neglected tropical diseases (27.07.2017)
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