Decoding myofibroblast origins in human kidney fibrosis
Kuppe, Christoph, Ibrahim, Mahmoud M., Kranz, Jennifer, Zhang, Xiaoting, Ziegler, Susanne, Perales-Patón, Javier, Jansen, Jitske, Reimer, Katharina C., Smith, James R., Dobie, Ross, Wilson-Kanamori, John R., Halder, Maurice, Xu, Yaoxian, Kabgani, Nazanin, Kaesler, Nadine, Klaus, Martin, Gernhold, Lukas, Puelles, Victor G., Huber, Tobias B., Boor, Peter, Menzel, Sylvia, Hoogenboezem, Remco M., Bindels, Eric M. J., Steffens, Joachim, Floege, Jürgen, Schneider, Rebekka K., Saez-Rodriguez, Julio, Henderson, Neil C., Kramann, Rafael
Published in Nature (London) (14.01.2021)
Published in Nature (London) (14.01.2021)
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Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation
Zhao, Manzhi, Kiernan, Caoimhe H., Stairiker, Christopher J., Hope, Jennifer L., Leon, Leticia G., van Meurs, Marjan, Brouwers-Haspels, Inge, Boers, Ruben, Boers, Joachim, Gribnau, Joost, van IJcken, Wilfred F. J., Bindels, Eric M., Hoogenboezem, Remco M., Erkeland, Stefan J., Mueller, Yvonne M., Katsikis, Peter D.
Published in PLoS pathogens (01.06.2020)
Published in PLoS pathogens (01.06.2020)
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The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape
de Jong, Madelon M. E., Kellermayer, Zoltán, Papazian, Natalie, Tahri, Sabrin, Hofste op Bruinink, Davine, Hoogenboezem, Remco, Sanders, Mathijs A., van de Woestijne, Pieter C., Bos, P. Koen, Khandanpour, Cyrus, Vermeulen, Jessica, Moreau, Philippe, van Duin, Mark, Broijl, Annemiek, Sonneveld, Pieter, Cupedo, Tom
Published in Nature immunology (01.06.2021)
Published in Nature immunology (01.06.2021)
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Journal Article
Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
Misund, Kristine, Hofste op Bruinink, Davine, Coward, Eivind, Hoogenboezem, Remco M., Rustad, Even Holth, Sanders, Mathijs A., Rye, Morten, Sponaas, Anne-Marit, van der Holt, Bronno, Zweegman, Sonja, Hovig, Eivind, Meza-Zepeda, Leonardo A., Sundan, Anders, Myklebost, Ola, Sonneveld, Pieter, Waage, Anders
Published in Leukemia (01.07.2022)
Published in Leukemia (01.07.2022)
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A single oncogenic enhancer rearrangement causes concomitant EVI1 and GATA2 deregulation in leukemia
Gröschel, Stefan, Sanders, Mathijs A, Hoogenboezem, Remco, de Wit, Elzo, Bouwman, Britta A M, Erpelinck, Claudia, van der Velden, Vincent H J, Havermans, Marije, Avellino, Roberto, van Lom, Kirsten, Rombouts, Elwin J, van Duin, Mark, Döhner, Konstanze, Beverloo, H Berna, Bradner, James E, Döhner, Hartmut, Löwenberg, Bob, Valk, Peter J M, Bindels, Eric M J, de Laat, Wouter, Delwel, Ruud
Published in Cell (10.04.2014)
Published in Cell (10.04.2014)
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Yap1-Driven Intestinal Repair Is Controlled by Group 3 Innate Lymphoid Cells
Romera-Hernández, Mónica, Aparicio-Domingo, Patricia, Papazian, Natalie, Karrich, Julien J., Cornelissen, Ferry, Hoogenboezem, Remco M., Samsom, Janneke N., Cupedo, Tom
Published in Cell reports (Cambridge) (07.01.2020)
Published in Cell reports (Cambridge) (07.01.2020)
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MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML
Sanders, Mathijs A., Chew, Edward, Flensburg, Christoffer, Zeilemaker, Annelieke, Miller, Sarah E., al Hinai, Adil S., Bajel, Ashish, Luiken, Bram, Rijken, Melissa, Mclennan, Tamara, Hoogenboezem, Remco M., Kavelaars, François G., Fröhling, Stefan, Blewitt, Marnie E., Bindels, Eric M., Alexander, Warren S., Löwenberg, Bob, Roberts, Andrew W., Valk, Peter J.M., Majewski, Ian J.
Published in Blood (04.10.2018)
Published in Blood (04.10.2018)
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Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome
Ribezzo, Flavia, Snoeren, Inge A. M., Ziegler, Susanne, Stoelben, Jacques, Olofsen, Patricia A., Henic, Almira, Ferreira, Monica Ventura, Chen, Si, Stalmann, Ursula S. A., Buesche, Guntram, Hoogenboezem, Remco M., Kramann, Rafael, Platzbecker, Uwe, Raaijmakers, Marc H. G. P., Ebert, Benjamin L., Schneider, Rebekka K.
Published in Leukemia (01.07.2019)
Published in Leukemia (01.07.2019)
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Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia
Smeenk, Leonie, Ottema, Sophie, Mulet-Lazaro, Roger, Ebert, Anja, Havermans, Marije, Varea, Andrea Arricibita, Fellner, Michaela, Pastoors, Dorien, van Herk, Stanley, Erpelinck-Verschueren, Claudia, Grob, Tim, Hoogenboezem, Remco M, Kavelaars, François G, Matson, Daniel R, Bresnick, Emery H, Bindels, Eric M, Kentsis, Alex, Zuber, Johannes, Delwel, Ruud
Published in Cancer discovery (01.11.2021)
Published in Cancer discovery (01.11.2021)
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An IL-1β-driven neutrophil–stromal cell axis fosters a BAFF-rich protumor microenvironment in individuals with multiple myeloma
de Jong, Madelon M. E., Fokkema, Cathelijne, Papazian, Natalie, Czeti, Ágnes, Appelman, Marjolein K., Vermeulen, Michael, van Heusden, Teddie, Hoogenboezem, Remco M., van Beek, Gregory, Tahri, Sabrin, Sanders, Mathijs A., van de Woestijne, Pieter C., Gay, Francesca, Moreau, Philippe, Büttner-Herold, Maike, Bruns, Heiko, van Duin, Mark, Broijl, Annemiek, Sonneveld, Pieter, Cupedo, Tom
Published in Nature immunology (01.05.2024)
Published in Nature immunology (01.05.2024)
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Myeloid cells promote interferon signaling-associated deterioration of the hematopoietic system
Feyen, Jacqueline, Ping, Zhen, Chen, Lanpeng, van Dijk, Claire, van Tienhoven, Tim V. D., van Strien, Paulina M. H., Hoogenboezem, Remco M., Wevers, Michiel J. W., Sanders, Mathijs A., Touw, Ivo P., Raaijmakers, Marc H. G. P.
Published in Nature communications (10.12.2022)
Published in Nature communications (10.12.2022)
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Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis
Skokowa, Julia, Steinemann, Doris, Katsman-Kuipers, Jenny E., Zeidler, Cornelia, Klimenkova, Olga, Klimiankou, Maksim, Ünalan, Murat, Kandabarau, Siarhei, Makaryan, Vahagn, Beekman, Renee, Behrens, Kira, Stocking, Carol, Obenauer, Julia, Schnittger, Susanne, Kohlmann, Alexander, Valkhof, Marijke G., Hoogenboezem, Remco, Göhring, Gudrun, Reinhardt, Dirk, Schlegelberger, Brigitte, Stanulla, Martin, Vandenberghe, Peter, Donadieu, Jean, Zwaan, C. Michel, Touw, Ivo P., van den Heuvel-Eibrink, Marry M., Dale, David C., Welte, Karl
Published in Blood (03.04.2014)
Published in Blood (03.04.2014)
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Cross-Tissue Transcriptomic Analysis of Human Secondary Lymphoid Organ-Residing ILC3s Reveals a Quiescent State in the Absence of Inflammation
Bar-Ephraim, Yotam E., Cornelissen, Ferry, Papazian, Natalie, Konijn, Tanja, Hoogenboezem, Remco M., Sanders, Mathijs A., Westerman, Bart A., Gönültas, Mehmet, Kwekkeboom, Jaap, Den Haan, Joke M.M., Reijmers, Rogier M., Mebius, Reina E., Cupedo, Tom
Published in Cell reports (Cambridge) (17.10.2017)
Published in Cell reports (Cambridge) (17.10.2017)
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Truncated CSF3 receptors induce pro‐inflammatory responses in severe congenital neutropenia
Olofsen, Patricia A., Bosch, Dennis A., Looper, Hans W. J., Strien, Paulina M. H., Hoogenboezem, Remco M., Roovers, Onno, Velden, Vincent H. J., Bindels, Eric M. J., De Pater, Emma M., Touw, Ivo P.
Published in British journal of haematology (01.01.2023)
Published in British journal of haematology (01.01.2023)
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An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation
Avellino, Roberto, Havermans, Marije, Erpelinck, Claudia, Sanders, Mathijs A., Hoogenboezem, Remco, van de Werken, Harmen J.G., Rombouts, Elwin, van Lom, Kirsten, van Strien, Paulina M.H., Gebhard, Claudia, Rehli, Michael, Pimanda, John, Beck, Dominik, Erkeland, Stefan, Kuiken, Thijs, de Looper, Hans, Gröschel, Stefan, Touw, Ivo, Bindels, Eric, Delwel, Ruud
Published in Blood (16.06.2016)
Published in Blood (16.06.2016)
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Identification of osteolineage cell‐derived extracellular vesicle cargo implicated in hematopoietic support
Morhayim, Jess, Ghebes, Corina A., Erkeland, Stefan J., Borg, Mariëtte N. D., Hoogenboezem, Remco M., Bindels, Eric M. J., Alphen, Floris P. J., Kassem, Moustapha, Wijnen, Andre J., Cornelissen, Jan J., Leeuwen, Johannes P., Eerden, Bram C. J., Voermans, Carlijn, Peppel, Jeroen, Braakman, Eric
Published in The FASEB journal (01.04.2020)
Published in The FASEB journal (01.04.2020)
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Activation of NF-κB driven inflammatory programs in mesenchymal elements attenuates hematopoiesis in low-risk myelodysplastic syndromes
Ping, Zhen, Chen, Si, Hermans, Sjoerd J. F., Kenswil, Keane J. G., Feyen, Jacqueline, van Dijk, Claire, Bindels, Eric M. J., Mylona, Athina M., Adisty, Niken M., Hoogenboezem, Remco M., Sanders, Mathijs A., Cremers, Eline M. P., Lindenbergh-Kortleve, Dicky J., Samsom, Janneke N., van de Loosdrecht, Arjan A., Raaijmakers, Marc H. G. P.
Published in Leukemia (01.02.2019)
Published in Leukemia (01.02.2019)
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Microfluidic evidence of synergistic effects between mesenchymal stromal cell-derived biochemical factors and biomechanical forces to control endothelial cell function
Zhang, Shuang, Tuk, Bastiaan, van de Peppel, Jeroen, Kremers, Gert-Jan, Koedam, Marijke, Pesch, Georg R., Rahman, Zaid, Hoogenboezem, Remco M., Bindels, Eric M.J., van Neck, Johan W., Boukany, Pouyan E., van Leeuwen, Johannes P.T.M., van der Eerden, Bram C.J.
Published in Acta biomaterialia (01.10.2022)
Published in Acta biomaterialia (01.10.2022)
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Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes
Zambetti, Noemi A, Bindels, Eric M J, Van Strien, Paulina M H, Valkhof, Marijke G, Adisty, Maria N, Hoogenboezem, Remco M, Sanders, Mathijs A, Rommens, Johanna M, Touw, Ivo P, Raaijmakers, Marc H G P
Published in Haematologica (Roma) (01.10.2015)
Published in Haematologica (Roma) (01.10.2015)
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Expression of Plet1 controls interstitial migration of murine small intestinal dendritic cells
Karrich, Julien J., Romera‐Hernández, Mónica, Papazian, Natalie, Veenbergen, Sharon, Cornelissen, Ferry, Aparicio‐Domingo, Patricia, Stenhouse, Frances H., Peddie, C. Diana, Hoogenboezem, Remco M., den Hollander, Chelsea W. J., Gaskell, Terri, Medley, Tanya, Boon, Louis, Blackburn, C. Clare, Withers, David R., Samsom, Janneke N., Cupedo, Tom
Published in European journal of immunology (01.02.2019)
Published in European journal of immunology (01.02.2019)
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