Architecture of a minimal signaling pathway explains the T-cell response to a 1 million-fold variation in antigen affinity and dose
Lever, Melissa, Lim, Hong-Sheng, Kruger, Philipp, Nguyen, John, Trendel, Nicola, Abu-Shah, Enas, Maini, Philip Kumar, van der Merwe, Philip Anton, Dushek, Omer
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2016)
Get full text
Journal Article
The contribution of major histocompatibility complex contacts to the affinity and kinetics of T cell receptor binding
Zhang, Hao, Lim, Hong-Sheng, Knapp, Berhard, Deane, Charlotte M, Aleksic, Milos, Dushek, Omer, van der Merwe, P Anton
Published in Scientific reports (13.10.2016)
Published in Scientific reports (13.10.2016)
Get full text
Journal Article
Costimulation of IL-2 Production through CD28 Is Dependent on the Size of Its Ligand
Lim, Hong-Sheng, Cordoba, Shaun-Paul, Dushek, Omer, Goyette, Jesse, Taylor, Alison, Rudd, Christopher E, van der Merwe, P Anton
Published in The Journal of immunology (1950) (01.12.2015)
Published in The Journal of immunology (1950) (01.12.2015)
Get full text
Journal Article
CD80 dimensions are important for T cell co-stimulation (P1396)
Lim, Hong-Sheng, Cordoba, Shaun-Paul, Goyette, Jesse, van der Merwe, Anton
Published in The Journal of immunology (1950) (01.05.2013)
Published in The Journal of immunology (1950) (01.05.2013)
Get full text
Journal Article
Architecture of a minimal signalling pathway explains the T cell response to a 1,000,000-fold variation in antigen affinity and dose
Lever, Melissa, Hong-Sheng, Lim, Kruger, Philipp, Nguyen, John, Trendel, Nicola, Abu-Shah, Enas, Maini, Philip K, Philip Anton Van Der Merwe, Dushek, Omer
Published in bioRxiv (27.08.2016)
Published in bioRxiv (27.08.2016)
Get full text
Paper