Protection of humans by plant glucosinolates: efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora
Fahey, Jed W, Wehage, Scott L, Holtzclaw, W David, Kensler, Thomas W, Egner, Patricia A, Shapiro, Theresa A, Talalay, Paul
Published in Cancer prevention research (Philadelphia, Pa.) (01.04.2012)
Published in Cancer prevention research (Philadelphia, Pa.) (01.04.2012)
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Direct Evidence That Sulfhydryl Groups of Keap1 Are the Sensors Regulating Induction of Phase 2 Enzymes That Protect against Carcinogens and Oxidants
Dinkova-Kostova, Albena T., Holtzclaw, W. David, Cole, Robert N., Itoh, Ken, Wakabayashi, Nobunao, Katoh, Yasutake, Yamamoto, Masayuki, Talalay, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (03.09.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (03.09.2002)
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Protection against Electrophile and Oxidant Stress by Induction of the Phase 2 Response: Fate of Cysteines of the Keap1 Sensor Modified by Inducers
Wakabayashi, Nobunao, Dinkova-Kostova, Albena T., Holtzclaw, W. David, Kang, Moon-Il, Kobayashi, Akira, Yamamoto, Masayuki, Kensler, Thomas W., Talalay, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2004)
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The Role of Keap1 in Cellular Protective Responses
Dinkova-Kostova, Albena T, Holtzclaw, W. David, Kensler, Thomas W
Published in Chemical research in toxicology (01.12.2005)
Published in Chemical research in toxicology (01.12.2005)
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Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model
Kalin, Jay H, Eroglu, Abdulkerim, Liu, Hua, Holtzclaw, W David, Leigh, Irene, Proby, Charlotte M, Fahey, Jed W, Cole, Philip A, Dinkova-Kostova, Albena T
Published in PloS one (13.03.2019)
Published in PloS one (13.03.2019)
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Extremely Potent Triterpenoid Inducers of the Phase 2 Response: Correlations of Protection against Oxidant and Inflammatory Stress
Dinkova-Kostova, Albena T., Liby, Karen T., Stephenson, Katherine K., Holtzclaw, W. David, Gao, Xiangqun, Suh, Nanjoo, Williams, Charlotte, Risingsong, Renee, Honda, Tadashi, Gribble, Gordon W., Sporn, Michael B., Talalay, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (22.03.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (22.03.2005)
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Inactivation of Tautomerase Activity of Macrophage Migration Inhibitory Factor by Sulforaphane: a Potential Biomarker for Anti-inflammatory Intervention
HEALY, Zachary R, HUA LIU, DAVID HOLTZCLAW, W, TALALAY, Paul
Published in Cancer epidemiology, biomarkers & prevention (01.07.2011)
Published in Cancer epidemiology, biomarkers & prevention (01.07.2011)
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Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase I study
Shapiro, T.A, Fahey, J.W, Dinkova-Kostova, A.T, Holtzclaw, W.D, Stephenson, K.K, Wade, K.L, Ye, L, Talalay, P
Published in Nutrition and cancer (01.01.2006)
Published in Nutrition and cancer (01.01.2006)
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Exceptionally Potent Inducer of Cytoprotective Enzymes: ELUCIDATION OF THE STRUCTURAL FEATURES THAT DETERMINE INDUCER POTENCY AND REACTIVITY WITH Keap1
Dinkova-Kostova, Albena T, Talalay, Paul, Sharkey, John, Zhang, Ying, Holtzclaw, W. David, Wang, Xiu Jun, David, Emilie, Schiavoni, Katherine H, Finlayson, Stewart, Mierke, Dale F, Honda, Tadashi
Published in The Journal of biological chemistry (29.10.2010)
Published in The Journal of biological chemistry (29.10.2010)
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Unexpected Genetic and Structural Relationships of a Long-Forgotten Flavoenzyme to NAD(P)H:Quinone Reductase (DT-Diaphorase)
Zhao, Qinjian, Yang, Xiao Ling, Holtzclaw, W. David, Talalay, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (04.03.1997)
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An Exceptionally Potent Inducer of Cytoprotective Enzymes
Dinkova-Kostova, Albena T., Talalay, Paul, Sharkey, John, Zhang, Ying, Holtzclaw, W. David, Wang, Xiu Jun, David, Emilie, Schiavoni, Katherine H., Finlayson, Stewart, Mierke, Dale F., Honda, Tadashi
Published in The Journal of biological chemistry (01.10.2010)
Published in The Journal of biological chemistry (01.10.2010)
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Journal Article
Chemical and Molecular Regulation of Enzymes that Detoxify Carcinogens
Prestera, Tory, Holtzclaw, W. David, Zhang, Yuesheng, Talalay, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (01.04.1993)
Published in Proceedings of the National Academy of Sciences - PNAS (01.04.1993)
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An unusual case of ‘uncompetitive activation’ by ascorbic acid: purification and kinetic properties of a myrosinase from Raphanus sativus seedlings
SHIKITA, Mikio, FAHEY, Jed W., GOLDEN, Tamara R., David HOLTZCLAW, W., TALALAY, Paul
Published in Biochemical journal (01.08.1999)
Published in Biochemical journal (01.08.1999)
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Journal Article
Chemoprotection against cancer by Phase 2 enzyme induction
Talalay, Paul, Fahey, Jed W., Holtzclaw, W.David, Prestera, Tory, Zhang, Yuesheng
Published in Toxicology Letters (01.12.1995)
Published in Toxicology Letters (01.12.1995)
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Conference Proceeding
Comprehensive Chromatographic and Spectroscopic Methods for the Separation and Identification of Intact Glucosinolates
Prestera, Tory, Fahey, Jed W., Holtzclaw, W.David, Abeygunawardana, Chitrananda, Kachinski, Joseph L., Talalay, Paul
Published in Analytical biochemistry (01.08.1996)
Published in Analytical biochemistry (01.08.1996)
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