Prevention of brain damage after traumatic brain injury by pharmacological enhancement of KCNQ (Kv7, “M-type”) K+ currents in neurons
Vigil, Fabio A, Bozdemir, Eda, Bugay, Vladislav, Chun, Sang H, Hobbs, MaryAnn, Sanchez, Isamar, Hastings, Shayne D, Veraza, Rafael J, Holstein, Deborah M, Sprague, Shane M, M Carver, Chase, Cavazos, Jose E, Brenner, Robert, Lechleiter, James D, Shapiro, Mark S
Published in Journal of cerebral blood flow and metabolism (01.06.2020)
Published in Journal of cerebral blood flow and metabolism (01.06.2020)
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Stimulation of astrocyte fatty acid oxidation by thyroid hormone is protective against ischemic stroke-induced damage
Sayre, Naomi L, Sifuentes, Mikaela, Holstein, Deborah, Cheng, Sheue-yann, Zhu, Xuguang, Lechleiter, James D
Published in Journal of cerebral blood flow and metabolism (01.02.2017)
Published in Journal of cerebral blood flow and metabolism (01.02.2017)
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P2Y1R-Initiated, IP3R-Dependent Stimulation of Astrocyte Mitochondrial Metabolism Reduces and Partially Reverses Ischemic Neuronal Damage in Mouse
Zheng, Wei, Watts, Lora Talley, Holstein, Deborah M, Wewer, Jimmy, Lechleiter, James D
Published in Journal of cerebral blood flow and metabolism (01.04.2013)
Published in Journal of cerebral blood flow and metabolism (01.04.2013)
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A Mouse Model of Repetitive Blast Traumatic Brain Injury Reveals Post-Trauma Seizures and Increased Neuronal Excitability
Bugay, Vladislav, Bozdemir, Eda, Vigil, Fabio A, Chun, Sang H, Holstein, Deborah M, Elliott, William R, Sprague, Cassie J, Cavazos, Jose E, Zamora, David O, Rule, Gregory, Shapiro, Mark S, Lechleiter, James D, Brenner, Robert
Published in Journal of neurotrauma (15.01.2020)
Published in Journal of neurotrauma (15.01.2020)
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Journal Article
Calcineurin β protects brain after injury by activating the unfolded protein response
Chen, Yanan, Holstein, Deborah M, Aime, Sofia, Bollo, Mariana, Lechleiter, James D
Published in Neurobiology of disease (01.10.2016)
Published in Neurobiology of disease (01.10.2016)
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Purinergic receptor stimulation reduces cytotoxic edema and brain infarcts in mouse induced by photothrombosis by energizing glial mitochondria
Zheng, Wei, Watts, Lora Talley, Holstein, Deborah M, Prajapati, Suresh I, Keller, Charles, Grass, Eileen H, Walter, Christi A, Lechleiter, James D
Published in PloS one (22.12.2010)
Published in PloS one (22.12.2010)
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Acute Treatment with the M-Channel (Kv7, KCNQ) Opener Retigabine Reduces the Long-Term Effects of Repetitive Blast Traumatic Brain Injuries
Vigil, Fabio A., Belchior, Hindiael, Bugay, Vladislav, Bazaldua, Isabella I., Stoja, Aiola, Dantas, Denise C., Chun, Sang H., Farmer, Austin, Bozdemir, Eda, Holstein, Deborah M., Cavazos, Jose E., Lechleiter, James D., Brenner, Robert, Shapiro, Mark S.
Published in Neurotherapeutics (01.04.2023)
Published in Neurotherapeutics (01.04.2023)
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Neuroprotective Roles of the Adenosine A3 Receptor Agonist AST-004 in Mouse Model of Traumatic Brain Injury
Bozdemir, Eda, Vigil, Fabio A., Chun, Sang H., Espinoza, Liliana, Bugay, Vladislav, Khoury, Sarah M., Holstein, Deborah M., Stoja, Aiola, Lozano, Damian, Tunca, Ceyda, Sprague, Shane M., Cavazos, Jose E., Brenner, Robert, Liston, Theodore E., Shapiro, Mark S., Lechleiter, James D.
Published in Neurotherapeutics (01.10.2021)
Published in Neurotherapeutics (01.10.2021)
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Nucleotide P2Y1 receptor agonists are in vitro and in vivo prodrugs of A1/A3 adenosine receptor agonists: implications for roles of P2Y1 and A1/A3 receptors in physiology and pathology
Liston, Theodore E., Hinz, Sonja, Müller, Christa E., Holstein, Deborah M., Wendling, Jay, Melton, Roger J., Campbell, Mary, Korinek, William S., Suresh, R. Rama, Sethre-Hofstad, Dane A., Gao, Zhan-Guo, Tosh, Dilip K., Jacobson, Kenneth A., Lechleiter, James D.
Published in Purinergic signalling (01.12.2020)
Published in Purinergic signalling (01.12.2020)
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Adenosine A1R/A3R agonist AST-004 reduces brain infarction in mouse and rat models of acute ischemic stroke
Fisher, Elizabeth S, Chen, Yanan, Sifuentes, Mikaela M, Stubblefield, Jeremy J, Lozano, Damian, Holstein, Deborah M, Ren, JingMei, Davenport, Matthew, DeRosa, Nicholas, Chen, Tsung-Pei, Nickel, Gerard, Liston, Theodore E, Lechleiter, James D
Published in Frontiers in stroke (01.01.2022)
Published in Frontiers in stroke (01.01.2022)
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The Trifunctional Protein Mediates Thyroid Hormone Receptor-Dependent Stimulation of Mitochondria Metabolism
Chocron, E. Sandra, Sayre, Naomi L, Holstein, Deborah, Saelim, Nuttawut, Ibdah, Jamal A, Dong, Lily Q, Zhu, Xuguang, Cheng, Sheue-Yann, Lechleiter, James D
Published in Molecular endocrinology (Baltimore, Md.) (01.07.2012)
Published in Molecular endocrinology (Baltimore, Md.) (01.07.2012)
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Corrigendum: Adenosine A1R/A3R agonist AST-004 reduces brain infarction in mouse and rat models of acute ischemic stroke
Fisher, Elizabeth S., Chen, Yanan, Sifuentes, Mikaela M., Stubblefield, Jeremy J., Lozano, Damian, Holstein, Deborah M., Ren, JingMei, Davenport, Matthew, DeRosa, Nicholas, Chen, Tsung-pei, Nickel, Gerard, Liston, Theodore E., Lechleiter, James D.
Published in Frontiers in stroke (29.01.2024)
Published in Frontiers in stroke (29.01.2024)
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Hyperglycemia-Induced Mitochondrial Dysfunction in Kidney and Brain Are Protected by β-Hydroxybutyrate Treatment: PO0693
Drel, Viktor, Holstein, Deborah, Kim, Jiwan J., Pamreddy, Annapurna, Lechleiter, James D., Sharma, Kumar
Published in Journal of the American Society of Nephrology (01.10.2021)
Published in Journal of the American Society of Nephrology (01.10.2021)
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Lack of Interactions Between Alteplase/Tenecteplase and the Adenosine A1R/A3R Agonist AST-004
Liston, Theodore E, Holstein, Deborah, Solt, Derek, Lozano, Damian, Korinek, William S, Lechleiter, James D
Published in Stroke (1970) (01.07.2024)
Published in Stroke (1970) (01.07.2024)
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HspB1 Overexpression Improves Life Span and Stress Resistance in an Invertebrate Model
Alexander, Courtney Carroll, Munkáscy, Erin, Tillmon, Haven, Fraker, Tamara, Scheirer, Jessica, Holstein, Deborah, Lozano, Damian, Khan, Maruf, Gidalevitz, Tali, Lechleiter, James D, Fisher, Alfred L, Zare, Habil, Rodriguez, Karl A
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (03.02.2022)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (03.02.2022)
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Ca2+ signalling system initiated by endoplasmic reticulum stress stimulates PERK activation
Feliziani, Constanza, Fernandez, Macarena, Quassollo, Gonzalo, Holstein, Deborah, Bairo, Sebastián M, Paton, James C, Paton, Adrienne W, de Batista, Juan, Lechleiter, James D, Bollo, Mariana
Published in Cell calcium (Edinburgh) (01.09.2022)
Published in Cell calcium (Edinburgh) (01.09.2022)
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Purinergic Receptor-Stimulated IP3-Mediated Ca2+ Release Enhances Neuroprotection by Increasing Astrocyte Mitochondrial Metabolism during Aging
Wu, Jun, Holstein, J. Deborah, Upadhyay, Geeta, Lin, Da-Ting, Conway, Stuart, Muller, Elizabeth, Lechleiter, James D
Published in The Journal of neuroscience (13.06.2007)
Published in The Journal of neuroscience (13.06.2007)
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