Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S
Sevenich, Lisa, Bowman, Robert L., Mason, Steven D., Quail, Daniela F., Rapaport, Franck, Elie, Benelita T., Brogi, Edi, Brastianos, Priscilla K., Hahn, William C., Holsinger, Leslie J., Massagué, Joan, Leslie, Christina S., Joyce, Johanna A.
Published in Nature cell biology (01.09.2014)
Published in Nature cell biology (01.09.2014)
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Journal Article
Treatment of Porphyromonas gulae infection and downstream pathology in the aged dog by lysine‐gingipain inhibitor COR388
Arastu‐Kapur, Shirin, Nguyen, Mai, Raha, Debasish, Ermini, Florian, Haditsch, Ursula, Araujo, Joseph, De Lannoy, Ines A. M., Ryder, Mark I., Dominy, Stephen S., Lynch, Casey, Holsinger, Leslie J.
Published in Pharmacology research & perspectives (01.02.2020)
Published in Pharmacology research & perspectives (01.02.2020)
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Journal Article
Multiple Erythematous-Yellow, Dome-Shaped Papules
Holsinger, J. Michael, DO, Campbell, Shannon M., DO, Witman, Patricia, MD
Published in American family physician (01.09.2010)
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Published in American family physician (01.09.2010)
Journal Article
Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors
Dominy, Stephen S, Lynch, Casey, Ermini, Florian, Benedyk, Malgorzata, Marczyk, Agata, Konradi, Andrei, Nguyen, Mai, Haditsch, Ursula, Raha, Debasish, Griffin, Christina, Holsinger, Leslie J, Arastu-Kapur, Shirin, Kaba, Samer, Lee, Alexander, Ryder, Mark I, Potempa, Barbara, Mydel, Piotr, Hellvard, Annelie, Adamowicz, Karina, Hasturk, Hatice, Walker, Glenn D, Reynolds, Eric C, Faull, Richard L M, Curtis, Maurice A, Dragunow, Mike, Potempa, Jan
Published in Science advances (01.01.2019)
Published in Science advances (01.01.2019)
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Journal Article
Alzheimer's Disease-Like Neurodegeneration in Porphyromonas gingivalis Infected Neurons with Persistent Expression of Active Gingipains
Haditsch, Ursula, Roth, Theresa, Rodriguez, Leo, Hancock, Sandy, Cecere, Thomas, Nguyen, Mai, Arastu-Kapur, Shirin, Broce, Sean, Raha, Debasish, Lynch, Casey C, Holsinger, Leslie J, Dominy, Stephen S, Ermini, Florian
Published in Journal of Alzheimer's disease (01.01.2020)
Published in Journal of Alzheimer's disease (01.01.2020)
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Journal Article
The Minimal Essential Core of a Cysteine-based Protein-tyrosine Phosphatase Revealed by a Novel 16-kDa VH1-like Phosphatase, VHZ
Alonso, Andres, Burkhalter, Stephen, Sasin, Joanna, Tautz, Lutz, Bogetz, Jori, Huynh, Huong, Bremer, Meire C D, Holsinger, Leslie J, Godzik, Adam, Mustelin, Tomas
Published in The Journal of biological chemistry (20.08.2004)
Published in The Journal of biological chemistry (20.08.2004)
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Journal Article
The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn)
Holsinger, Leslie J, Ward, Kevin, Duffield, Bill, Zachwieja, Joseph, Jallal, Bahija
Published in Oncogene (10.10.2002)
Published in Oncogene (10.10.2002)
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Journal Article
Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction
Holsinger, L.J., Graef, I.A., Swat, W., Chi, T., Bautista, D.M., Davidson, L., Lewis, R.S., Alt, F.W., Crabtree, G.R.
Published in Current biology (07.05.1998)
Published in Current biology (07.05.1998)
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Journal Article
Eosinophilic angiocentric fibrosis
Holsinger, J Michael, Magro, Cynthia, Allen, Carl, Powell, David, Agrawal, Amit
Published in Journal of otolaryngology-head and neck surgery (01.10.2008)
Published in Journal of otolaryngology-head and neck surgery (01.10.2008)
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Journal Article
Dermatology: a specialty that exemplifies the osteopathic medical profession
Campbell, Shannon M, Sammons, Dawn L, Sarsama-Nixon, Ramona M, Holsinger, J Michael, Stephenson, Sean, Walkowski, Stevan
Published in The Journal of the American Osteopathic Association (01.05.2011)
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Published in The Journal of the American Osteopathic Association (01.05.2011)
Journal Article
Increased levels of phospho‐tau217 in neuron cultures and CVN mice infected with Porphyromonas gingivalis
Ermini, Florian, Haditsch, Ursula, Rodriguez, Leo, Martinez‐Horta, Aurora, Broce, Sean, Raha, Debasish, Nguyen, Mai, Kapur, Shirin, Lynch, Casey C, Holsinger, Leslie J, Dominy, Stephen S
Published in Alzheimer's & dementia (01.12.2021)
Published in Alzheimer's & dementia (01.12.2021)
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Journal Article
Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model
Elie, Benelita Tina, Gocheva, Vasilena, Shree, Tanaya, Dalrymple, Stacie A., Holsinger, Leslie J., Joyce, Johanna A.
Published in Biochimie (01.11.2010)
Published in Biochimie (01.11.2010)
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Journal Article
Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70
Graef, Isabella A., Holsinger, Leslie J., Diver, Steve, Schreiber, Stuart L., Crabtree, Gerald R.
Published in The EMBO journal (15.09.1997)
Published in The EMBO journal (15.09.1997)
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Journal Article
Analysis of the posttranslational modifications of the influenza virus M2 protein
Holsinger, L J, Shaughnessy, M A, Micko, A, Pinto, L H, Lamb, R A
Published in Journal of Virology (01.02.1995)
Published in Journal of Virology (01.02.1995)
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Journal Article