Topical versus Systemic Antimicrobial Therapy for Treating Mildly Infected Diabetic Foot Ulcers: A Randomized, Controlled, Double-Blinded, Multicenter Trial of Pexiganan Cream
Lipsky, Benjamin A., Holroyd, Kenneth J., Zasloff, Michael
Published in Clinical infectious diseases (15.12.2008)
Published in Clinical infectious diseases (15.12.2008)
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Human and Machine Intelligence Together Drive Drug Repurposing in Rare Diseases
Challa, Anup P, Zaleski, Nicole M, Jerome, Rebecca N, Lavieri, Robert R, Shirey-Rice, Jana K, Barnado, April, Lindsell, Christopher J, Aronoff, David M, Crofford, Leslie J, Harris, Raymond C, Alp Ikizler, T, Mayer, Ingrid A, Holroyd, Kenneth J, Pulley, Jill M
Published in Frontiers in genetics (28.07.2021)
Published in Frontiers in genetics (28.07.2021)
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In Vitro Antibacterial Properties of Pexiganan, an Analog of Magainin
Ge, Y, MacDonald, D L, Holroyd, K J, Thornsberry, C, Wexler, H, Zasloff, M
Published in Antimicrobial Agents and Chemotherapy (01.04.1999)
Published in Antimicrobial Agents and Chemotherapy (01.04.1999)
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A Phase I/IIA Trial of Continuous Five-Day Infusion of Squalamine Lactate (MSI-1256F) Plus Carboplatin and Paclitaxel in Patients with Advanced Non-Small Cell Lung Cancer
HERBST, Roy S, HAMMOND, Lisa A, SOLOMON, Stephen, SCHILLER, Joan H, CARBONE, David P, TRAN, Hai T, HOLROYD, Kenneth J, DESAI, Avinash, WILLIAMS, Jon I, NEBIYOU BEKELE, B, HAIT, Howard, ALLGOOD, Victoria
Published in Clinical cancer research (15.09.2003)
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Published in Clinical cancer research (15.09.2003)
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Interleukin 9: A Candidate Gene for Asthma
Nicolaides, Nicholas C., Holroyd, Kenneth J., Ewart, Susan L., Eleff, Scott M., Kiser, Matthew B., Dragwa, Carl R., Sullivan, Christine D., Grasso, Luigi, Zhang, Liu-Yi, Messler, Carol J., Zhou, Tingyi, Kleeberger, Steven R., Buetow, Kenneth H., Levitt, Roy C.
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.1997)
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A Phase I and Pharmacokinetic Study of Squalamine, a Novel Antiangiogenic Agent, in Patients with Advanced Cancers
BHARGAVA, Pankaj, MARSHALL, John L, DAHUT, William, RIZVI, Naiyer, TROCKY, Nina, WILLIAMS, Jon I, HAIT, Howard, SONG, Sharon, HOLROYD, Kenneth J, HAWKINS, Michael J
Published in Clinical cancer research (01.12.2001)
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Published in Clinical cancer research (01.12.2001)
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Leveraging Human Genetics to Identify Safety Signals Prior to Drug Marketing Approval and Clinical Use
Jerome, Rebecca N., Joly, Meghan Morrison, Kennedy, Nan, Shirey-Rice, Jana K., Roden, Dan M., Bernard, Gordon R., Holroyd, Kenneth J., Denny, Joshua C., Pulley, Jill M.
Published in Drug safety (01.06.2020)
Published in Drug safety (01.06.2020)
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A Phase I and Pharmacokinetic Study of Squalamine, an Aminosterol Angiogenesis Inhibitor
HAO, Desirée, HAMMOND, Lisa A, WILLIAMS, Jon I, HOLROYD, Kenneth J, ROWINSKY, Eric K, ECKHARDT, S. Gail, PATNAIK, Amita, TAKIMOTO, Chris H, SCHWARTZ, Garry H, GOETZ, Andrew D, TOLCHER, Anthony W, MCCREERY, Heather A, MAMUN, Khalid
Published in Clinical cancer research (01.07.2003)
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Published in Clinical cancer research (01.07.2003)
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Squalamine Treatment of Human Tumors in nu/nu Mice Enhances Platinum-based Chemotherapies
WILLIAMS, Jon I, WEITMAN, Steven, VON HOFF, Daniel D, GONZALEZ, Cristina M, JUNDT, Carita H, MARTY, Jennifer, STRINGER, Stephanie D, HOLROYD, Kenneth J, MCLANE, Michael P, QIMING CHEN, ZASLOFF, Michael
Published in Clinical cancer research (01.03.2001)
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Published in Clinical cancer research (01.03.2001)
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Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics
Pulley, Jill M, Shirey-Rice, Jana K, Lavieri, Robert R, Jerome, Rebecca N, Zaleski, Nicole M, Aronoff, David M, Bastarache, Lisa, Niu, Xinnan, Holroyd, Kenneth J, Roden, Dan M, Skaar, Eric P, Niswender, Colleen M, Marnett, Lawrence J, Lindsley, Craig W, Ekstrom, Leeland B, Bentley, Alan R, Bernard, Gordon R, Hong, Charles C, Denny, Joshua C
Published in Assay and drug development technologies (01.04.2017)
Published in Assay and drug development technologies (01.04.2017)
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Advocating for mutually beneficial access to shelved compounds
Pulley, Jill M, Jerome, Rebecca N, Shirey-Rice, Jana K, Zaleski, Nicole M, Naylor, Helen M, Pruijssers, Andrea J, Jackson, James C, Bernard, Gordon R, Holroyd, Kenneth J
Published in Future medicinal chemistry (01.06.2018)
Published in Future medicinal chemistry (01.06.2018)
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Increased expression of the calcium-activated chloride channel hCLCA1 in airways of patients with obstructive chronic bronchitis
Hauber, Hans-Peter, Bergeron, Celine, Tsicopoulos, Anne, Wallaert, Benoit, Olivenstein, Ron, Holroyd, Kenneth J, Levitt, Roy C, Hamid, Qutayba
Published in Canadian respiratory journal (2005)
Published in Canadian respiratory journal (2005)
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Motivation for Launching a Cancer Metastasis Inhibition (CMI) Program
Pulley, Jill M., Jerome, Rebecca N., Ogletree, Martin L., Bernard, Gordon R., Lavieri, Robert R., Zaleski, Nicole M., Hong, Charles C., Shirey-Rice, Jana K., Arteaga, Carlos L., Mayer, Ingrid A., Holroyd, Kenneth J., Cook, Rebecca S.
Published in Targeted oncology (01.02.2018)
Published in Targeted oncology (01.02.2018)
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When Enough Is Enough: Decision Criteria for Moving a Known Drug into Clinical Testing for a New Indication in the Absence of Preclinical Efficacy Data
Pulley, Jill M, Jerome, Rebecca N, Zaleski, Nicole M, Shirey-Rice, Jana K, Pruijssers, Andrea J, Lavieri, Robert R, Chettiar, Somsundaram N, Naylor, Helen M, Aronoff, David M, Edwards, David A, Niswender, Colleen M, Dugan, Laura L, Crofford, Leslie J, Bernard, Gordon R, Holroyd, Kenneth J
Published in Assay and drug development technologies (01.12.2017)
Published in Assay and drug development technologies (01.12.2017)
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IL-9 and its receptor in allergic and nonallergic lung disease: Increased expression in asthma
Shimbara, Ayako, Christodoulopoulos, Pota, Soussi-Gounni, Abdelilah, Olivenstein, Ronald, Nakamura, Yutaka, Levitt, Roy C., Nicolaides, Nicholas C., Holroyd, Kenneth J., Tsicopoulos, Anne, Lafitte, Jean-Jacques, Wallaert, Benoit, Hamid, Qutayba A.
Published in Journal of allergy and clinical immunology (01.01.2000)
Published in Journal of allergy and clinical immunology (01.01.2000)
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Up-Regulation of Interleukin-9 and the Interleukin-9-Associated Calcium-Activated Chloride Channel hCLCA1 in Nasal Mucosa Following In Vivo Allergen Challenge
Hauber, Hans-Peter, Bergeron, Celine, Toda, Masao, Kontolemos, Mario, Holroyd, Kenneth J, Levitt, Roy C, Hamid, Qutayba
Published in Allergy, asthma, and clinical immunology (15.03.2007)
Published in Allergy, asthma, and clinical immunology (15.03.2007)
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Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for Atopy
Postma, Dirkje S, Bleecker, Eugene R, Amelung, Pamela J, Holroyd, Kenneth J, Xu, Jianfeng, Panhuysen, Carolien I.M, Meyers, Deborah A, Levitt, Roy C
Published in The New England journal of medicine (05.10.1995)
Published in The New England journal of medicine (05.10.1995)
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Interleukin-9 Promotes Allergen-Induced Eosinophilic Inflammation and Airway Hyperresponsiveness in Transgenic Mice
McLane, Michael P, Haczku, Angela, van de Rijn, Matthijs, Weiss, Christine, Ferrante, Veronica, MacDonald, Dorothy, Renauld, Jean-Christophe, Nicolaides, Nicholas C, Holroyd, Kenneth J, Levitt, Roy C
Published in American journal of respiratory cell and molecular biology (01.11.1998)
Published in American journal of respiratory cell and molecular biology (01.11.1998)
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Linkage analysis of susceptibility to ozone-induced lung inflammation in inbred mice
Kleeberger, Steven R, Levitt, Roy C, Zhang, Liu-Yi, Longphre, Malinda, Harkema, Jack, Jedlicka, Anne, Eleff, Scott M, DiSilvestre, Deborah, Holroyd, Kenneth J
Published in Nature genetics (01.12.1997)
Published in Nature genetics (01.12.1997)
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