Mesenchymal Stromal Cells and Their Extracellular Vesicles Enhance the Anti-Inflammatory Phenotype of Regulatory Macrophages by Downregulating the Production of Interleukin (IL)-23 and IL-22
Hyvärinen, Kati, Holopainen, Minna, Skirdenko, Vita, Ruhanen, Hanna, Lehenkari, Petri, Korhonen, Matti, Käkelä, Reijo, Laitinen, Saara, Kerkelä, Erja
Published in Frontiers in immunology (12.04.2018)
Published in Frontiers in immunology (12.04.2018)
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Journal Article
Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules
Valkonen, Sami, Holopainen, Minna, Colas, Romain A., Impola, Ulla, Dalli, Jesmond, Käkelä, Reijo, Siljander, Pia R.-M., Laitinen, Saara
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.08.2019)
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.08.2019)
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Journal Article
Fatty acid fingerprints in bronchoalveolar lavage fluid and its extracellular vesicles reflect equine asthma severity
Höglund, Nina, Nieminen, Petteri, Mustonen, Anne-Mari, Käkelä, Reijo, Tollis, Sylvain, Koho, Ninna, Holopainen, Minna, Ruhanen, Hanna, Mykkänen, Anna
Published in Scientific reports (17.06.2023)
Published in Scientific reports (17.06.2023)
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Journal Article
Metabolism and phospholipid assembly of polyunsaturated fatty acids in human bone marrow mesenchymal stromal cells1
Tigistu-Sahle, Feven, Lampinen, Milla, Kilpinen, Lotta, Holopainen, Minna, Lehenkari, Petri, Laitinen, Saara, Käkelä, Reijo
Published in Journal of lipid research (01.01.2017)
Published in Journal of lipid research (01.01.2017)
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Journal Article
Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization
Le Joncour, Vadim, Filppu, Pauliina, Hyvönen, Maija, Holopainen, Minna, Turunen, S Pauliina, Sihto, Harri, Burghardt, Isabel, Joensuu, Heikki, Tynninen, Olli, Jääskeläinen, Juha, Weller, Michael, Lehti, Kaisa, Käkelä, Reijo, Laakkonen, Pirjo
Published in EMBO molecular medicine (01.06.2019)
Published in EMBO molecular medicine (01.06.2019)
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Journal Article
Metabolism and phospholipid assembly of polyunsaturated fatty acids in human bone marrow mesenchymal stromal cells
Tigistu-Sahle, Feven, Lampinen, Milla, Kilpinen, Lotta, Holopainen, Minna, Lehenkari, Petri, Laitinen, Saara, Käkelä, Reijo
Published in Journal of lipid research (01.01.2017)
Published in Journal of lipid research (01.01.2017)
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Journal Article
Fatty acid profiles reveal dietary variability of a large calanoid copepod Limnocalanus macrurus in the northern Baltic Sea
von Weissenberg, Ella, Ruhanen, Hanna, Holopainen, Minna, Käkelä, Reijo, Engström-Öst, Jonna
Published in Frontiers in Marine Science (07.02.2024)
Published in Frontiers in Marine Science (07.02.2024)
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Journal Article
Repetitive amiodarone administration causes liver damage via adipose tissue ER stress-dependent lipolysis, leading to hepatotoxic free fatty acid accumulation
Hubel, Einav, Fishman, Sigal, Holopainen, Minna, Käkelä, Reijo, Shaffer, Ortal, Houri, Inbal, Zvibel, Isabel, Shibolet, Oren
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2021)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.09.2021)
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Journal Article
Improvement of high-density lipoprotein atheroprotective properties in patients with systemic lupus erythematosus after belimumab treatment
Dedemadi, Anastasia-Georgia, Gkolfinopoulou, Christina, Nikoleri, Dimitra, Nikoloudaki, Myrto, Ruhanen, Hanna, Holopainen, Minna, Kakela, Reijo, Christopoulou, Georgia, Bournazos, Stavros, Constantoulakis, Pantelis, Sidiropoulos, Prodromos, Bertsias, George, Chroni, Angeliki
Published in Rheumatology (Oxford, England) (21.03.2024)
Published in Rheumatology (Oxford, England) (21.03.2024)
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Journal Article
Small mitochondrial protein NERCLIN regulates cardiolipin homeostasis and mitochondrial ultrastructure
Konovalova, Svetlana, Torregrosa-Muñumer, Rubén, Manjunath, Pooja, Liu, Xiaonan, Baral, Sundar, Fatima, Kaneez, Holopainen, Minna, Kvist, Jouni, Rajendran, Jayasimman, Yang, Yang, Varjosalo, Markku, Käkelä, Reijo, Somerharju, Pentti, Tyynismaa, Henna
Published in Proceedings of the National Academy of Sciences - PNAS (25.07.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (25.07.2023)
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Journal Article
Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells
Holopainen, Minna, Colas, Romain A., Valkonen, Sami, Tigistu-Sahle, Feven, Hyvärinen, Kati, Mazzacuva, Francesca, Lehenkari, Petri, Käkelä, Reijo, Dalli, Jesmond, Kerkelä, Erja, Laitinen, Saara
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.10.2019)
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01.10.2019)
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Journal Article
Abstract LB-055: Novel therapeutic option targeting the tumor cell lysosomes
Joncour, Vadim Le, Filppu, Pauliina, Holopainen, Minna, Hyvönen, Maija, Turunen, S. Pauliina, Sihto, Harri, Burghardt, Isabel, Jääskeläinen, Juha, Weller, Michael, Lehti, Kaisa, Käkela, Reijo, Laakkonen, Pirjo
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Low-Density Lipoprotein Particles Carrying Proinflammatory Proteins with Altered Aggregation Pattern Detected in COVID-19 Patients 3 Months After HospitalizationRunning title: Low-Density Lipoprotein Particles in COVID-19 Patients
Ueland, Thor, Äikäs, Lauri A.O., Dahl, Tuva B., Gregersen, Ida, Olsen, Maria Belland, Michelsen, Annika, Schanke, Ylva, Holopainen, Minna, Ruhanen, Hanna, Singh, Sachin, Tveita, Anders Aune, Finbråten, Ane-Kristine, Heggelund, Lars, Trøseid, Marius, Dyrhol-Riise, Anne Ma, Nyman, Tuula A., Holven, Kirsten B, Öörni, Katariina, Aukrust, Pål, Halvorsen, Bente
Published in The Journal of infection (21.02.2023)
Published in The Journal of infection (21.02.2023)
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Journal Article
Low-density lipoprotein particles carrying proinflammatory proteins with altered aggregation pattern detected in COVID-19 patients 3 months after hospitalization
Ueland, Thor, Äikäs, Lauri A O, Dahl, Tuva B, Gregersen, Ida, Olsen, Maria Belland, Michelsen, Annika, Schanke, Ylva, Holopainen, Minna, Ruhanen, Hanna, Singh, Sachin, Tveita, Anders Aune, Finbråten, Ane-Kristine, Heggelund, Lars, Trøseid, Marius, Dyrhol-Riise, Anne Ma, Nyman, Tuula A, Holven, Kirsten B, Öörni, Katariina, Aukrust, Pål, Halvorsen, Bente
Published in The Journal of infection (01.05.2023)
Published in The Journal of infection (01.05.2023)
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Journal Article
Lipidomic changes of LDL after consumption of Camelina sativa oil, fatty fish and lean fish in subjects with impaired glucose metabolism—A randomized controlled trial
Erkkilä, Arja T., Manninen, Suvi, Fredrikson, Linda, Bhalke, Monika, Holopainen, Minna, Ruuth, Maija, Lankinen, Maria, Käkelä, Reijo, Öörni, Katariina, Schwab, Ursula S.
Published in Journal of clinical lipidology (01.09.2021)
Published in Journal of clinical lipidology (01.09.2021)
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Journal Article