Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double-blind, placebo-controlled clinical trial
Dellinger, Ryan W, Holmes, Holly E, Hu-Seliger, Tina, Butt, Rodney W, Harrison, Stephen A, Mozaffarian, Dariush, Chen, Oliver, Guarente, Leonard
Published in Hepatology (Baltimore, Md.) (01.09.2023)
Published in Hepatology (Baltimore, Md.) (01.09.2023)
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Journal Article
Efficacy and tolerability of EH301 for amyotrophic lateral sclerosis: a randomized, double-blind, placebo-controlled human pilot study
de la Rubia, JosÉ E., Drehmer, Eraci, Platero, JosÉ L., Benlloch, MarÍa, Caplliure-Llopis, Jordi, Villaron-Casales, Carlos, de Bernardo, Nieves, AlarcÓn, Jorge, Fuente, Cristian, Carrera, Sandra, Sancho, David, GarcÍa-Pardo, Pilar, Pascual, Raquel, JuÁrez, Marta, Cuerda-Ballester, María, Forner, Alfonso, Sancho-Castillo, Sandra, Barrios, Carlos, Obrador, Elena, Marchio, Patricia, Salvador, Rosario, Holmes, Holly E., Dellinger, Ryan W., Guarente, Leonard, Estrela, José M.
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (02.01.2019)
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (02.01.2019)
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Journal Article
Study the Longitudinal in vivo and Cross-Sectional ex vivo Brain Volume Difference for Disease Progression and Treatment Effect on Mouse Model of Tauopathy Using Automated MRI Structural Parcellation
Ma, Da, Holmes, Holly E, Cardoso, Manuel J, Modat, Marc, Harrison, Ian F, Powell, Nick M, O'Callaghan, James M, Ismail, Ozama, Johnson, Ross A, O'Neill, Michael J, Collins, Emily C, Beg, Mirza F, Popuri, Karteek, Lythgoe, Mark F, Ourselin, Sebastien
Published in Frontiers in neuroscience (24.01.2019)
Published in Frontiers in neuroscience (24.01.2019)
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Journal Article
Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome
Powell, Nick M, Modat, Marc, Cardoso, M Jorge, Ma, Da, Holmes, Holly E, Yu, Yichao, O'Callaghan, James, Cleary, Jon O, Sinclair, Ben, Wiseman, Frances K, Tybulewicz, Victor L J, Fisher, Elizabeth M C, Lythgoe, Mark F, Ourselin, Sébastien
Published in PloS one (22.09.2016)
Published in PloS one (22.09.2016)
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Journal Article
In Vivo Imaging of Tau Pathology Using Magnetic Resonance Imaging Textural Analysis
Colgan, Niall, Ganeshan, Balaji, Harrison, Ian F, Ismail, Ozama, Holmes, Holly E, Wells, Jack A, Powell, Nick M, O'Callaghan, James M, O'Neill, Michael J, Murray, Tracey K, Ahmed, Zeshan, Collins, Emily C, Johnson, Ross A, Groves, Ashley, Lythgoe, Mark F
Published in Frontiers in neuroscience (06.11.2017)
Published in Frontiers in neuroscience (06.11.2017)
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Journal Article
Gene expression profiles in sporadic ALS fibroblasts define disease subtypes and the metabolic effects of the investigational drug EH301
Fels, Jasmine A, Casalena, Gabriella, Konrad, Csaba, Holmes, Holly E, Dellinger, Ryan W, Manfredi, Giovanni
Published in Human molecular genetics (10.10.2022)
Published in Human molecular genetics (10.10.2022)
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Journal Article
Elevated homocysteine is associated with increased rates of epigenetic aging in a population with mild cognitive impairment
Holmes, Holly E., Valentin, Rafael E., Jernerén, Fredrik, de Jager Loots, Celeste A., Refsum, Helga, Smith, A. David, Guarente, Leonard, Dellinger, Ryan W., Sampson, Dayle
Published in Aging cell (27.06.2024)
Published in Aging cell (27.06.2024)
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Journal Article
Safety Assessment of High-Purity, Synthetic Nicotinamide Riboside (NR-E) in a 90-Day Repeated Dose Oral Toxicity Study, With a 28-Day Recovery Arm
Marinescu, Anca G, Chen, Jayson, Holmes, Holly E, Guarente, Leonard, Mendes, Odete, Morris, Mark, Dellinger, Ryan W
Published in International journal of toxicology (01.07.2020)
Published in International journal of toxicology (01.07.2020)
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Journal Article
Imaging the accumulation and suppression of tau pathology using multiparametric MRI
Holmes, Holly E, Colgan, Niall, Ismail, Ozama, Ma, Da, Powell, Nick M, O'Callaghan, James M, Harrison, Ian F, Johnson, Ross A, Murray, Tracey K, Ahmed, Zeshan, Heggenes, Morton, Fisher, Alice, Cardoso, M.J, Modat, Marc, Walker-Samuel, Simon, Fisher, Elizabeth M.C, Ourselin, Sebastien, O'Neill, Michael J, Wells, Jack A, Collins, Emily C, Lythgoe, Mark F
Published in Neurobiology of aging (01.03.2016)
Published in Neurobiology of aging (01.03.2016)
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Journal Article
Increased Cerebral Vascular Reactivity in the Tau Expressing rTg4510 Mouse: Evidence against the Role of Tau Pathology to Impair Vascular Health in Alzheimer's Disease
Wells, Jack A, Holmes, Holly E, O'Callaghan, James M, Colgan, Niall, Ismail, Ozama, Fisher, Elizabeth MC, Siow, Bernard, Murray, Tracey K, Schwarz, Adam J, O'Neill, Michael J, Collins, Emily C, Lythgoe, Mark F
Published in Journal of cerebral blood flow and metabolism (01.03.2015)
Published in Journal of cerebral blood flow and metabolism (01.03.2015)
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Journal Article
AN IMAGING STRATEGY TO CHARACTERISE TAU PATHOLOGY IN VIVO IN A MODEL OF ALZHEIMER'S DISEASE USING MULTI-PARAMETRIC MRI
Holmes, Holly E, Ismail, Ozama, Wells, Jack, O'Callaghan, James, Powell, Nicholas, Murray, Tracey, Ahmed, Zehshan, O'Neill, Michael, Collins, Emily, Johnson, Ross, Colgan, Niall, Lythgoe, Mark F
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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Journal Article
P2‐026: HYPOPERFUSION IN THE ABSENCE OF APP GENE TRIPLICATION IN THE TC1 MOUSE MODEL OF DOWN's SYNDROME
Holmes, Holly E., Wiseman, Frances, O'Callaghan, James M., Wells, Jack, Tybulewicz, Victor L.J., Fisher, Elizabeth M.C., Lythgoe, Mark F.
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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Journal Article
HYPOPERFUSION IN THE ABSENCE OF APP GENE TRIPLICATION IN THE TC1 MOUSE MODEL OF DOWN’S SYNDROME
Holmes, Holly E., Wiseman, Frances, O'Callaghan, James M., Wells, Jack, Tybulewicz, Victor L.J., Fisher, Elizabeth M.C., Lythgoe, Mark F.
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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Journal Article
IC‐P‐211: AN IMAGING STRATEGY TO CHARACTERISE TAU PATHOLOGY IN VIVO IN A MODEL OF ALZHEIMER'S DISEASE USING MULTI‐PARAMETRIC MRI
Holmes, Holly E., Ismail, Ozama, Wells, Jack, O'Callaghan, James, Powell, Nicholas, Murray, Tracey, Ahmed, Zehshan, O'Neill, Michael, Collins, Emily, Johnson, Ross, Colgan, Niall, Lythgoe, Mark F.
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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Journal Article
Fully-Automated MMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome
Powell, Nick M, Modat, Marc, Cardoso, M Jorge, Ma, Da, Holmes, Holly E, Yu, Yichao, O'Callaghan, James, Cleary, Jon O, Sinclair, Ben, Wiseman, Frances K
Published in PloS one (01.09.2016)
Published in PloS one (01.09.2016)
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Journal Article
HYPOPERFUSION IN THE ABSENCE OF APP GENE TRIPLICATION IN THE TC1 MOUSE MODEL OF DOWN’S SYNDROME
Holmes, Holly E, Wiseman, Frances, O'Callaghan, James M, Wells, Jack, Tybulewicz, Victor L.J, Fisher, Elizabeth M.C, Lythgoe, Mark F
Published in Alzheimer's & dementia (2014)
Published in Alzheimer's & dementia (2014)
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Journal Article