Mitochondrial dysfunction in aging and longevity: a causal or protective role?
Pulliam, Daniel A, Bhattacharya, Arunabh, Van Remmen, Holly
Published in Antioxidants & redox signaling (20.10.2013)
Published in Antioxidants & redox signaling (20.10.2013)
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A new mouse model of frailty: the Cu/Zn superoxide dismutase knockout mouse
Deepa, Sathyaseelan S., Bhaskaran, Shylesh, Espinoza, Sara, Brooks, Susan V., McArdle, Anne, Jackson, Malcolm J., Van Remmen, Holly, Richardson, Arlan
Published in GeroScience (01.04.2017)
Published in GeroScience (01.04.2017)
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Skeletal muscle weakness due to deficiency of CuZn-superoxide dismutase is associated with loss of functional innervation
Larkin, Lisa M, Davis, Carol S, Sims-Robinson, Catrina, Kostrominova, Tatiana Y, Van Remmen, Holly, Richardson, Arlan, Feldman, Eva L, Brooks, Susan V
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.11.2011)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.11.2011)
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Elevated phospholipid hydroperoxide glutathione peroxidase (GPX4) expression modulates oxylipin formation and inhibits age-related skeletal muscle atrophy and weakness
Czyżowska, Agnieszka, Brown, Jacob, Xu, Hongyang, Sataranatarajan, Kavitha, Kinter, Michael, Tyrell, Victoria J., O'Donnell, Valerie B., Van Remmen, Holly
Published in Redox biology (01.08.2023)
Published in Redox biology (01.08.2023)
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Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching
Ahn, Bumsoo, Ranjit, Rojina, Premkumar, Pavithra, Pharaoh, Gavin, Piekarz, Katarzyna M., Matsuzaki, Satoshi, Claflin, Dennis R., Riddle, Kaitlyn, Judge, Jennifer, Bhaskaran, Shylesh, Satara Natarajan, Kavithalakshmi, Barboza, Erika, Wronowski, Benjamin, Kinter, Michael, Humphries, Kenneth M., Griffin, Timothy M., Freeman, Willard M., Richardson, Arlan, Brooks, Susan V., Van Remmen, Holly
Published in Journal of cachexia, sarcopenia and muscle (01.04.2019)
Published in Journal of cachexia, sarcopenia and muscle (01.04.2019)
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High oxidative damage levels in the longest‐living rodent, the naked mole‐rat
Andziak, Blazej, O’Connor, Timothy P., Qi, Wenbo, DeWaal, Eric M., Pierce, Anson, Chaudhuri, Asish R., Van Remmen, Holly, Buffenstein, Rochelle
Published in Aging cell (01.12.2006)
Published in Aging cell (01.12.2006)
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Cancer cachexia in a mouse model of oxidative stress
Brown, Jacob L., Lawrence, Marcus M., Ahn, Bumsoo, Kneis, Parker, Piekarz, Katarzyna M., Qaisar, Rizwan, Ranjit, Rojina, Bian, Jan, Pharaoh, Gavin, Brown, Chase, Peelor, Fredrick F., Kinter, Michael T., Miller, Benjamin F., Richardson, Arlan, Van Remmen, Holly
Published in Journal of cachexia, sarcopenia and muscle (01.12.2020)
Published in Journal of cachexia, sarcopenia and muscle (01.12.2020)
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CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life
ELCHURI, Sailaja, OBERLEY, Terry D, WENBO QI, EISENSTEIN, Richard S, ROBERTS, L. Jackson, VAN REMMEN, Holly, EPSTEIN, Charles J, HUANG, Ting-Ting
Published in Oncogene (13.01.2005)
Published in Oncogene (13.01.2005)
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Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels
Lustgarten, Michael S., Bhattacharya, Arunabh, Muller, Florian L., Jang, Youngmok C., Shimizu, Takahiko, Shirasawa, Takuji, Richardson, Arlan, Van Remmen, Holly
Published in Biochemical and biophysical research communications (08.06.2012)
Published in Biochemical and biophysical research communications (08.06.2012)
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Glutathione peroxidase 4 differentially regulates the release of apoptogenic proteins from mitochondria
Liang, Hanyu, Ran, Qitao, Jang, Youngmok Charles, Holstein, Deborah, Lechleiter, James, McDonald-Marsh, Tiffany, Musatov, Andrej, Song, Wook, Van Remmen, Holly, Richardson, Arlan
Published in Free radical biology & medicine (01.08.2009)
Published in Free radical biology & medicine (01.08.2009)
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Age Related Changes in Muscle Mass and Force Generation in the Triple Transgenic (3xTgAD) Mouse Model of Alzheimer's Disease
Xu, Hongyang, Bhaskaran, Shylesh, Piekarz, Katarzyna M, Ranjit, Rojina, Bian, Jan, Kneis, Parker, Ellis, Aubrey, Bhandari, Suyesha, Rice, Heather C, Van Remmen, Holly
Published in Frontiers in aging neuroscience (25.04.2022)
Published in Frontiers in aging neuroscience (25.04.2022)
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The lack of CuZnSOD leads to impaired neurotransmitter release, neuromuscular junction destabilization and reduced muscle strength in mice
Shi, Yun, Ivannikov, Maxim V, Walsh, Michael E, Liu, Yuhong, Zhang, Yiqiang, Jaramillo, Carlos A, Macleod, Gregory T, Van Remmen, Holly
Published in PloS one (27.06.2014)
Published in PloS one (27.06.2014)
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Neuronal deletion of MnSOD in mice leads to demyelination, inflammation and progressive paralysis that mimics phenotypes associated with progressive multiple sclerosis
Bhaskaran, Shylesh, Kumar, Gaurav, Thadathil, Nidheesh, Piekarz, Katarzyna M., Mohammed, Sabira, Lopez, Sergio Dominguez, Qaisar, Rizwan, Walton, Dorothy, Brown, Jacob L., Murphy, Ashley, Smith, Nataliya, Saunders, Debra, Beckstead, Michael J., Plafker, Scott, Lewis, Tommy L., Towner, Rheal, Deepa, Sathyaseelan S., Richardson, Arlan, Axtell, Robert C., Van Remmen, Holly
Published in Redox biology (01.02.2023)
Published in Redox biology (01.02.2023)
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Lipid hydroperoxides and oxylipins are mediators of denervation induced muscle atrophy
Brown, Jacob L., Peelor, Fredrick F., Georgescu, Constantin, Wren, Jonathan D., Kinter, Michael, Tyrrell, Victoria J., O'Donnell, Valerie B., Miller, Benjamin F., Van Remmen, Holly
Published in Redox biology (01.11.2022)
Published in Redox biology (01.11.2022)
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Determining the contributions of protein synthesis and breakdown to muscle atrophy requires non‐steady‐state equations
Kobak, Kamil A., Lawrence, Marcus M., Pharaoh, Gavin, Borowik, Agnieszka K., Peelor, Frederick F., Shipman, Patrick D., Griffin, Timothy M., Van Remmen, Holly, Miller, Benjamin F.
Published in Journal of cachexia, sarcopenia and muscle (01.12.2021)
Published in Journal of cachexia, sarcopenia and muscle (01.12.2021)
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Dietary restriction attenuates age‐associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD
Jang, Young C., Liu, Yuhong, Hayworth, Christopher R., Bhattacharya, Arunabh, Lustgarten, Michael S., Muller, Florian L., Chaudhuri, Asish, Qi, Wenbo, Li, Yan, Huang, Jing‐Yi, Verdin, Eric, Richardson, Arlan, Van Remmen, Holly
Published in Aging cell (01.10.2012)
Published in Aging cell (01.10.2012)
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Lifelong reduction in complex IV induces tissue‐specific metabolic effects but does not reduce lifespan or healthspan in mice
Deepa, Sathyaseelan S., Pharaoh, Gavin, Kinter, Michael, Diaz, Vivian, Fok, Wilson C., Riddle, Kaitlyn, Pulliam, Daniel, Hill, Shauna, Fischer, Kathleen E., Soto, Vanessa, Georgescu, Constantin, Wren, Jonathan D., Viscomi, Carlo, Richardson, Arlan, Van Remmen, Holly
Published in Aging cell (01.08.2018)
Published in Aging cell (01.08.2018)
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A Novel Stable Isotope Approach Demonstrates Surprising Degree of Age-Related Decline in Skeletal Muscle Collagen Proteostasis
Abbott, Claire B, Lawrence, Marcus M, Kobak, Kamil A, Lopes, Erika Barboza Prado, Peelor, 3rd, Frederick F, Donald, Elizabeth J, Van Remmen, Holly, Griffin, Timothy M, Miller, Benjamin F
Published in Function (Oxford, England) (01.01.2021)
Published in Function (Oxford, England) (01.01.2021)
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