Efficacy of a short course of specific immunotherapy in patients with allergic rhinoconjunctivitis to ragweed pollen
Patel, Piyush, MD, Holdich, Tom, MBBS, Fischer von Weikersthal-Drachenberg, Karl J., MD, Huber, Birgit, PhD
Published in Journal of allergy and clinical immunology (01.01.2014)
Published in Journal of allergy and clinical immunology (01.01.2014)
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Phase I clinical trial evaluating the safety and efficacy of ADP-A2M10 SPEAR T cells in patients with MAGE-A10+ advanced non-small cell lung cancer
Blumenschein, George R, Devarakonda, Siddhartha, Johnson, Melissa, Moreno, Victor, Gainor, Justin, Edelman, Martin J, Heymach, John V, Govindan, Ramaswamy, Bachier, Carlos, Doger de Spéville, Bernard, Frigault, Matthew J, Olszanski, Anthony J, Lam, Vincent K, Hyland, Natalie, Navenot, Jean-Marc, Fayngerts, Svetlana, Wolchinsky, Zohar, Broad, Robyn, Batrakou, Dzmitry, Pentony, Melissa M, Sanderson, Joseph P, Gerry, Andrew, Marks, Diane, Bai, Jane, Holdich, Tom, Norry, Elliot, Fracasso, Paula M
Published in Journal for immunotherapy of cancer (01.01.2022)
Published in Journal for immunotherapy of cancer (01.01.2022)
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Journal Article
Ultrashort-specific immunotherapy successfully treats seasonal allergic rhinoconjunctivitis to grass pollen
DuBuske, Lawrence M., Frew, Anthony J., Horak, Friedrich, Keith, Paul K., Corrigan, Christopher J., Aberer, Werner, Holdich, Tom, von Weikersthal-Drachenberg, Karl J. Fischer
Published in Allergy and asthma proceedings (01.05.2011)
Published in Allergy and asthma proceedings (01.05.2011)
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Journal Article
NY-ESO-1–specific TCR–engineered T cells mediate sustained antigen-specific antitumor effects in myeloma
Rapoport, Aaron P, Stadtmauer, Edward A, Binder-Scholl, Gwendolyn K, Goloubeva, Olga, Vogl, Dan T, Lacey, Simon F, Badros, Ashraf Z, Garfall, Alfred, Weiss, Brendan, Finklestein, Jeffrey, Kulikovskaya, Irina, Sinha, Sanjoy K, Kronsberg, Shari, Gupta, Minnal, Bond, Sarah, Melchiori, Luca, Brewer, Joanna E, Bennett, Alan D, Gerry, Andrew B, Pumphrey, Nicholas J, Williams, Daniel, Tayton- Martin, Helen K, Ribeiro, Lilliam, Holdich, Tom, Yanovich, Saul, Hardy, Nancy, Yared, Jean, Kerr, Naseem, Philip, Sunita, Westphal, Sandra, Siegel, Don L, Levine, Bruce L, Jakobsen, Bent K, Kalos, Michael, June, Carl H
Published in Nature medicine (01.08.2015)
Published in Nature medicine (01.08.2015)
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Abstract 2564: Selection of affinity-enhanced T-cell receptors for adoptive T-cell therapy targeting MAGE-A10
Border, Ellen, Sanderson, Joseph P., Weissensteiner, Thomas, Hyland, Natalie, Holdich, Tom, Brophy, Francine, Amado, Rafael, Gerry, Andrew, Pumphrey, Nicholas
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Phase I/IIa Study of Genetically Engineered NY-ESO-1 SPEAR T-Cells Administered Following Autologous Stem Cell Transplant in HLA-a02+ Patients with Advanced Multiple Myeloma: Long Term Follow-up (NCT01352286)
Rapoport, Aaron P., Stadtmauer, Edward A, Chagin, Karen, Faitg, Thomas, Iyengar, Malini, Trivedi, Trupti, Norry, Elliot, Holdich, Tom, Binder-Scholl, Gwendolyn, Amado, Rafael, Fang, Frank
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Two phase I/II open label clinical trials evaluating the safety and efficacy of autologous T cells expressing enhanced TCRs specific for NY-ESO-1 or MAGE-A10 in subjects with stage IIIb or stage IV non-small cell lung cancer (NCT02588612/NCT02592577)
Creelan, Ben C., Gainor, Justin F., Govindan, Ramaswamy, Hardy, Nancy M., Heymach, John, Mudad, Raja, Reckamp, Karen L., Bardwell, William, Holdich, Tom, Bartlett-Pandite, Arundathy N., Amado, Rafael G.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Initial safety assessment of MAGE-A10 c796 TCR T-cells in two clinical trials
Lam, Vincent K., Hong, David S., Heymach, John, Blumenschein, George R., Creelan, Ben C., Bradbury, Penelope Ann, Butler, Marcus O., Gainor, Justin F., Govindan, Ramaswamy, Johnson, Melissa Lynne, Mudad, Raja, Sullivan, Ryan J., Brophy, Francine, Hyland, Natalie, Chagin, Karen, Holdich, Tom, Norry, Elliot, Amado, Rafael G.
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Autologous genetically engineered NY-ESO-1 c259 T in HLA-A02:01, HLA02:05 and HLA02:06 positive patients with NY-ESO-1 expressing tumors
Mackall, Crystal, D'Angelo, Sandra P., Grupp, Stephan A., Odunsi, Kunle, Cristea, Mihaela C., Linette, Gerald P., Kluger, Harriet M., Kari, Gabor, Pandite, Lini, Holdich, Tom, Norry, Elliot, Binder-Scholl, Gwendolyn, Amado, Rafael G.
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Cytokine release syndrome (CRS) in patients treated with NY-ESO-1 c259 TCR
Mackall, Crystal, D'Angelo, Sandra P., Cristea, Mihaela C., Odunsi, Kunle, Norry, Elliot, Pandite, Lini, Holdich, Tom, Kari, Gabor, Ramachandran, Indu R., Ribeiro, Lilliam, Binder-Scholl, Gwendolyn, Amado, Rafael G.
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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Open label, non-randomized, multi-cohort pilot study of genetically engineered NY-ESO-1 specific NY-ESO-1 c259 t in HLA-A2 + patients with synovial sarcoma (NCT01343043)
Mackall, Crystal, Tap, William D., Glod, John, Druta, Mihaela, Chow, Warren Allen, Araujo, Dejka M., Grupp, Stephan A., Van Tine, Brian Andrew, Chagin, Karen, Van Winkle, Erin, Kari, Gabor, Trivedi, Trupti, Norry, Elliot, Holdich, Tom, Bartlett-Pandite, Arundathy N., Amado, Rafael G., D'Angelo, Sandra P.
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1c259T Cells in Synovial Sarcoma
D'Angelo, Sandra P., Melchiori, Luca, Merchant, Melinda S., Bernstein, Donna, Glod, John, Kaplan, Rosandra, Grupp, Stephan, Tap, William D., Chagin, Karen, Binder, Gwendolyn K., Basu, Samik, Lowther, Daniel E., Wang, Ruoxi, Bath, Natalie, Tipping, Alex, Betts, Gareth, Ramachandran, Indu, Navenot, Jean-Marc, Zhang, Hua, Wells, Daniel K., Winkle, Erin Van, Kari, Gabor, Trivedi, Trupti, Holdich, Tom, Pandite, Lini, Amado, Rafael, Mackall, Crystal L.
Published in Cancer discovery (11.06.2018)
Published in Cancer discovery (11.06.2018)
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Journal Article
Genetically engineered NY-ESO-1 specific T cells in HLA-A201+ patients with advanced cancers
Merchant, Melinda S., Cristea, Mihaela C., Stadtmauer, Edward A., Tap, William D., D'Angelo, Sandra P., Grupp, Stephan A., Holdich, Tom, Binder-Scholl, Gwendolyn, Jakobsen, Bent K, Odunsi, Kunle, Rapoport, Aaron, Mackall, Crystal
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article
Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial Sarcoma
D'Angelo, Sandra P., Melchiori, Luca, Merchant, Melinda S., Bernstein, Donna, Glod, John, Kaplan, Rosandra, Grupp, Stephan, Tap, William D., Chagin, Karen, Binder, Gwendolyn K., Basu, Samik, Lowther, Daniel E., Wang, Ruoxi, Bath, Natalie, Tipping, Alex, Betts, Gareth, Ramachandran, Indu, Navenot, Jean-Marc, Zhang, Hua, Wells, Daniel K., Van Winkle, Erin, Kari, Gabor, Trivedi, Trupti, Holdich, Tom, Pandite, Lini, Amado, Rafael, Mackall, Crystal L.
Published in Cancer discovery (01.08.2018)
Published in Cancer discovery (01.08.2018)
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Journal Article
Abstract 4707: Genetically engineered NY-ESO-1-specific T cells in HLA-A2+ patients with synovial sarcoma
Merchant, Melinda S., D'Angelo, Sandra P., Zhang, Hua, Bernstein, Donna, Binder-Scholl, Gwen, Holdich, Tom, Melchiori, Luca, Williams, Dan, Fortin, Marylene, Peretz, Yoav, Howe, Jason, Mehler, Michael, Hug, Bruce A., Wright, Matthew, Grupp, Stephen, Meyers, Paul A., Tap, William, Jakobsen, Bent, Mackall, Crystal L.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 4701: NY-ESO T cells administered post ASCT for MM exhibit extended functionality without exhaustion in a natural pattern of effector and memory programming
Rapoport, Aaron, Stadtmauer, Edward, Melchiori, Luca, Wong, Ryan, Davila, Eduardo, Binder-Scholl, Gwendolyn, Holdich, Tom, Vogl, Dan, Weiss, Brendan, Finkelstein, Jeffrey, Lacey, Simon, Bond, Sarah, Fortin, Marylene, Peretz, Yoav, Brewer, Joanna, Bennett, Alan, Gerry, Andrew, Pumphrey, Nick, Tayton-Martin, Helen, Ribeiro, Lilliam, Badros, Ashraf, Yanovich, Saul, Hardy, Nancy, Yared, Jean, Kerr, Naseem, Philip, Sunita, Wesphal, Sandra, Levine, Bruce L., June, Carl, Kalos, Michael, Jakobsen, Bent
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259 T Cells in Synovial Sarcoma
D'Angelo, Sandra P, Melchiori, Luca, Merchant, Melinda S, Bernstein, Donna, Glod, John, Kaplan, Rosandra, Grupp, Stephan, Tap, William D, Chagin, Karen, Binder, Gwendolyn K, Basu, Samik, Lowther, Daniel E, Wang, Ruoxi, Bath, Natalie, Tipping, Alex, Betts, Gareth, Ramachandran, Indu, Navenot, Jean-Marc, Zhang, Hua, Wells, Daniel K, Van Winkle, Erin, Kari, Gabor, Trivedi, Trupti, Holdich, Tom, Pandite, Lini, Amado, Rafael, Mackall, Crystal L
Published in Cancer discovery (01.08.2018)
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Published in Cancer discovery (01.08.2018)
Journal Article
Optimizing engineered TCR T cell therapy for synovial sarcoma
D'Angelo, Sandra, Merchant, Melinda, Melchiori, Luca, Zhang, Hua, Pandite, Lini, Holdich, Tom, Binder-Scholl, Gwendolyn, Tap, William, Fortin, Marylene, Peretz, Yoav, Wright, Matthew, Meyers, Paul, Amado, Rafael, Jakobsen, Bent, Mackall, Crystal
Published in Journal for immunotherapy of cancer (04.11.2015)
Published in Journal for immunotherapy of cancer (04.11.2015)
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