Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys
Tao, Yunlong, Vermilyea, Scott C., Zammit, Matthew, Lu, Jianfeng, Olsen, Miles, Metzger, Jeanette M., Yao, Lin, Chen, Yuejun, Phillips, Sean, Holden, James E., Bondarenko, Viktoriya, Block, Walter F., Barnhart, Todd E., Schultz-Darken, Nancy, Brunner, Kevin, Simmons, Heather, Christian, Bradley T., Emborg, Marina E., Zhang, Su-Chun
Published in Nature medicine (01.04.2021)
Published in Nature medicine (01.04.2021)
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Induced Pluripotent Stem Cell-Derived Neural Cells Survive and Mature in the Nonhuman Primate Brain
Emborg, Marina E., Liu, Yan, Xi, Jiajie, Zhang, Xiaoqing, Yin, Yingnan, Lu, Jianfeng, Joers, Valerie, Swanson, Christine, Holden, James E., Zhang, Su-Chun
Published in Cell reports (Cambridge) (28.03.2013)
Published in Cell reports (Cambridge) (28.03.2013)
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Striatal delivery of CERE-120, an AAV2 vector encoding human neurturin, enhances activity of the dopaminergic nigrostriatal system in aged monkeys
Herzog, Christopher D., Dass, Biplob, Holden, James E., Stansell III, James, Gasmi, Mehdi, Tuszynski, Mark H., Bartus, Raymond T., Kordower, Jeffrey H.
Published in Movement disorders (15.06.2007)
Published in Movement disorders (15.06.2007)
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Neurodegeneration Prevented by Lentiviral Vector Delivery of GDNF in Primate Models of Parkinson's Disease
Kordower, Jeffrey H., Emborg, Marina E., Bloch, Jocelyne, Ma, Shuang Y., Chu, Yaping, Leventhal, Liza, McBride, Jodi, Chen, Er-Yun, Palfi, Stéphane, Roitberg, Ben Zion, Brown, W. Douglas, Holden, James E., Pyzalski, Robert, Taylor, Michael D., Carvey, Paul, Ling, ZaoDung, Trono, Didier, Hantraye, Philippe, Déglon, Nicole, Aebischer, Patrick
Published in Science (American Association for the Advancement of Science) (27.10.2000)
Published in Science (American Association for the Advancement of Science) (27.10.2000)
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Subthalamic glutamic acid decarboxylase gene therapy: changes in motor function and cortical metabolism
Emborg, Marina E, Carbon, Maren, Holden, James E, During, Matthew J, Ma, Yilong, Tang, Chengke, Moirano, Jeffrey, Fitzsimons, Helen, Roitberg, Ben Z, Tuccar, Eray, Roberts, Andrew, Kaplitt, Michael G, Eidelberg, David
Published in Journal of cerebral blood flow and metabolism (01.03.2007)
Published in Journal of cerebral blood flow and metabolism (01.03.2007)
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PET Measures of D1, D2, and DAT Binding Are Associated With Heightened Tactile Responsivity in Rhesus Macaques: Implications for Sensory Processing Disorder
Schneider, Mary L, Moore, Colleen F, Ahlers, Elizabeth O, Barnhart, Todd E, Christian, Bradley T, DeJesus, Onofre T, Engle, Jonathan W, Holden, James E, Larson, Julie A, Moirano, Jeffrey M, Murali, Dhanabalan, Nickles, Robert J, Resch, Leslie M, Converse, Alexander K
Published in Frontiers in integrative neuroscience (17.07.2019)
Published in Frontiers in integrative neuroscience (17.07.2019)
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In vivo imaging of inflammation and oxidative stress in a nonhuman primate model of cardiac sympathetic neurodegeneration
Metzger, Jeanette M., Moore, Colleen F., Boettcher, Carissa A., Brunner, Kevin G., Fleddermann, Rachel A., Matsoff, Helen N., Resnikoff, Henry A., Bondarenko, Viktoriya, Kamp, Timothy J., Hacker, Timothy A., Barnhart, Todd E., Lao, Patrick J., Christian, Bradley T., Nickles, R. Jerry, Gallagher, Catherine L., Holden, James E., Emborg, Marina E.
Published in NPJ Parkinson's Disease (13.07.2018)
Published in NPJ Parkinson's Disease (13.07.2018)
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Metabolic rate in the right amygdala predicts negative affect in depressed patients
Abercrombie, H C, Schaefer, S M, Larson, C L, Oakes, T R, Lindgren, K A, Holden, J E, Perlman, S B, Turski, P A, Krahn, D D, Benca, R M, Davidson, R J
Published in Neuroreport (05.10.1998)
Published in Neuroreport (05.10.1998)
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Nonuniform cardiac denervation observed by 11C-meta-hydroxyephedrine PET in 6-OHDA-treated monkeys
Joers, Valerie, Seneczko, Kailie, Goecks, Nichole C, Kamp, Timothy J, Hacker, Timothy A, Brunner, Kevin G, Engle, Jonathan W, Barnhart, Todd E, Nickles, R Jerome, Holden, James E, Emborg, Marina E
Published in PloS one (2012)
Published in PloS one (2012)
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A Reversible Tracer Analysis Approach to the Study of Effective Dopamine Turnover
Sossi, Vesna, Doudet, Doris J., Holden, James E.
Published in Journal of cerebral blood flow and metabolism (01.04.2001)
Published in Journal of cerebral blood flow and metabolism (01.04.2001)
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Improved kinetic analysis of dynamic PET data with optimized HYPR-LR
Floberg, John M, Mistretta, Charles A, Weichert, Jamey P, Hall, Lance T, Holden, James E, Christian, Bradley T
Published in Medical physics (Lancaster) (01.06.2012)
Published in Medical physics (Lancaster) (01.06.2012)
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In-vivo Measurement of LDOPA Uptake, Dopamine Reserve and Turnover in the Rat Brain Using [18F]FDOPA PET
Walker, Matthew D, Dinelle, Katherine, Kornelsen, Rick, McCormick, Siobhan, Mah, Chenoa, Holden, James E, Farrer, Matthew J, Stoessl, A Jon, Sossi, Vesna
Published in Journal of cerebral blood flow and metabolism (01.01.2013)
Published in Journal of cerebral blood flow and metabolism (01.01.2013)
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A method for partial volume correction of PET-imaged tumor heterogeneity using expectation maximization with a spatially varying point spread function
Barbee, David L, Flynn, Ryan T, Holden, James E, Nickles, Robert J, Jeraj, Robert
Published in Physics in medicine & biology (07.01.2010)
Published in Physics in medicine & biology (07.01.2010)
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Prenatal Stress Induces Increased Striatal Dopamine Transporter Binding in Adult Nonhuman Primates
Converse, Alexander K, Moore, Colleen F, Moirano, Jeffrey M, Ahlers, Elizabeth O, Larson, Julie A, Engle, Jonathan W, Barnhart, Todd E, Murali, Dhanabalan, Christian, Bradley T, DeJesus, Onofre T, Holden, James E, Nickles, Robert J, Schneider, Mary L
Published in Biological psychiatry (1969) (01.10.2013)
Published in Biological psychiatry (1969) (01.10.2013)
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Moderate-Level Prenatal Alcohol Exposure Induces Sex Differences in Dopamine D1 Receptor Binding in Adult Rhesus Monkeys
Converse, Alexander K., Moore, Colleen F., Holden, James E., Ahlers, Elizabeth O., Moirano, Jeffrey M., Larson, Julie A., Resch, Leslie M., DeJesus, Onofre T., Barnhart, Todd E., Nickles, Robert J., Murali, Dhanabalan, Christian, Bradley T., Schneider, Mary L.
Published in Alcoholism, clinical and experimental research (01.12.2014)
Published in Alcoholism, clinical and experimental research (01.12.2014)
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In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease
Lee, Chong S., Samii, Ali, Sossi, Vesna, Ruth, Thomas J., Schulzer, Michael, Holden, James E., Wudel, Jess, Pal, Pramod K., De La Fuente-Fernandez, Raul, Calne, Donald B., Stoessl, A. Jon
Published in Annals of neurology (01.04.2000)
Published in Annals of neurology (01.04.2000)
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Dopamine transporter relation to levodopa-derived synaptic dopamine in a rat model of Parkinson's: an in vivo imaging study
Sossi, Vesna, Dinelle, Katherine, Topping, Geoffrey J, Holden, James E, Doudet, Doris, Schulzer, Michael, Ruth, Thomas J, Stoessl, A. Jon, de la Fuente-Fernandez, Raul
Published in Journal of neurochemistry (01.04.2009)
Published in Journal of neurochemistry (01.04.2009)
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A dual-tracer study of extrastriatal 6-[18F]fluoro-m-tyrosine and 6-[18F]-fluoro-l-dopa Uptake in Parkinson's disease
Li, Clarence T., Palotti, Matthew, Holden, James E., Oh, Jen, Okonkwo, Ozioma, Christian, Bradley T., Bendlin, Barbara B., Buyan-Dent, Laura, Harding, Sandra J., Stone, Charles K., DeJesus, Onofre T., Nickles, Robert J., Gallagher, Catherine L.
Published in Synapse (New York, N.Y.) (01.08.2014)
Published in Synapse (New York, N.Y.) (01.08.2014)
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