Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors
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Published in Microbiology (Society for General Microbiology) (01.05.2012)
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Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma
Scanu, Tiziana, Spaapen, Robbert M., Bakker, Jeroen M., Pratap, Chandra Bhan, Wu, Lin-en, Hofland, Ingrid, Broeks, Annegien, Shukla, Vijay Kumar, Kumar, Mohan, Janssen, Hans, Song, Ji-Ying, Neefjes-Borst, E. Andra, te Riele, Hein, Holden, David W., Nath, Gopal, Neefjes, Jacques
Published in Cell host & microbe (10.06.2015)
Published in Cell host & microbe (10.06.2015)
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Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death
Thurston, Teresa L. M., Matthews, Sophie A., Jennings, Elliott, Alix, Eric, Shao, Feng, Shenoy, Avinash R., Birrell, Mark A., Holden, David W.
Published in Nature communications (03.11.2016)
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The Salmonella Effector SteD Mediates MARCH8-Dependent Ubiquitination of MHC II Molecules and Inhibits T Cell Activation
Bayer-Santos, Ethel, Durkin, Charlotte H., Rigano, Luciano A., Kupz, Andreas, Alix, Eric, Cerny, Ondrej, Jennings, Elliott, Liu, Mei, Ryan, Aindrias S., Lapaque, Nicolas, Kaufmann, Stefan H.E., Holden, David W.
Published in Cell host & microbe (09.11.2016)
Published in Cell host & microbe (09.11.2016)
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The Salmonella deubiquitinase SseL inhibits selective autophagy of cytosolic aggregates
Mesquita, Francisco S, Thomas, Mair, Sachse, Martin, Santos, António J M, Figueira, Rita, Holden, David W
Published in PLoS pathogens (01.06.2012)
Published in PLoS pathogens (01.06.2012)
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CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD
Cerny, Ondrej, Godlee, Camilla, Tocci, Romina, Cross, Nancy E, Shi, Haoran, Williamson, James C, Alix, Eric, Lehner, Paul J, Holden, David W
Published in PLoS pathogens (01.07.2021)
Published in PLoS pathogens (01.07.2021)
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PLEKHM1 Regulates Salmonella-Containing Vacuole Biogenesis and Infection
McEwan, David G., Richter, Benjamin, Claudi, Beatrice, Wigge, Christoph, Wild, Philipp, Farhan, Hesso, McGourty, Kieran, Coxon, Fraser P., Franz-Wachtel, Mirita, Perdu, Bram, Akutsu, Masato, Habermann, Anja, Kirchof, Anja, Helfrich, Miep H., Odgren, Paul R., Van Hul, Wim, Frangakis, Achilleas S., Rajalingam, Krishnaraj, Macek, Boris, Holden, David W., Bumann, Dirk, Dikic, Ivan
Published in Cell host & microbe (14.01.2015)
Published in Cell host & microbe (14.01.2015)
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The Salmonella transmembrane effector SteD hijacks AP1-mediated vesicular trafficking for delivery to antigen-loading MHCII compartments
Godlee, Camilla, Cerny, Ondrej, Liu, Mei, Blundell, Samkeliso, Gallagher, Alanna E, Shahin, Meriam, Holden, David W
Published in PLoS pathogens (01.05.2022)
Published in PLoS pathogens (01.05.2022)
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Modulation of Salmonella virulence by a novel SPI-2 injectisome effector that interacts with the dystrophin-associated protein complex
Yu, Xiu-Jun, Xie, Haixia, Li, Yan, Liu, Mei, Hou, Ruhong, Predeus, Alexander V, Perez Sepulveda, Blanca M, Hinton, Jay C D, Holden, David W, Thurston, Teresa L M
Published in mBio (17.07.2024)
Published in mBio (17.07.2024)
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Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism
Matthews-Palmer, Teige R.S., Gonzalez-Rodriguez, Nayim, Calcraft, Thomas, Lagercrantz, Signe, Zachs, Tobias, Yu, Xiu-Jun, Grabe, Grzegorz J., Holden, David W., Nans, Andrea, Rosenthal, Peter B., Rouse, Sarah L., Beeby, Morgan
Published in Journal of structural biology (01.06.2021)
Published in Journal of structural biology (01.06.2021)
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SseL, a Salmonella deubiquitinase required for macrophage killing and virulence
Rytkönen, Anne, Poh, John, Garmendia, Junkal, Boyle, Cliona, Thompson, Arthur, Liu, Mei, Freemont, Paul, Hinton, Jay C.D, Holden, David W
Published in Proceedings of the National Academy of Sciences - PNAS (27.02.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (27.02.2007)
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The Salmonella Kinase SteC Targets the MAP Kinase MEK to Regulate the Host Actin Cytoskeleton
Odendall, Charlotte, Rolhion, Nathalie, Förster, Andreas, Poh, John, Lamont, Douglas J., Liu, Mei, Freemont, Paul S., Catling, Andrew D., Holden, David W.
Published in Cell host & microbe (15.11.2012)
Published in Cell host & microbe (15.11.2012)
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