The International Serious Adverse Events Consortium
Holden, Arthur L., Contreras, Jorge L., John, Sally, Nelson, Matthew R.
Published in Nature reviews. Drug discovery (01.11.2014)
Published in Nature reviews. Drug discovery (01.11.2014)
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Journal Article
Phenotype standardization for drug-induced kidney disease
Mehta, Ravindra L., Awdishu, Linda, Davenport, Andrew, Murray, Patrick T., Macedo, Etienne, Cerda, Jorge, Chakaravarthi, Raj, Holden, Arthur L., Goldstein, Stuart L.
Published in Kidney international (01.08.2015)
Published in Kidney international (01.08.2015)
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Journal Article
6 Thiopurine Induced Pancreatitis in Inflammatory Bowel Disease: Clinical Features and Genetic Determinants
Heap, Graham A, Singh, Abhey, Bewshea, Claire M, Weedon, Michael, Dubois, Patrick, Andrews, Jane M, Annese, Vito, Bampton, Peter A, Bell, Sally, Cole, Andy, Connor, Susan J, Creed, Tom, D'Amato, Mauro, Fedorak, Richard N, Florin, Timothy H, Gaya, Daniel R, Greig, Emma, Halfvarson, Jonas, Irving, Peter M, Karban, Amir, Lawrance, Ian C, Lev-Tzion, Raffi, Lindsay, James O, Mawsley, Joel, Mazher, Zia, Orchard, Timothy R, Radford-Smith, Graham L, Reffitt, David, Silverberg, Mark S, Sturniolo, Giacomo C, Tsianos, Epameinondas V, Walsh, Alissa, Zeissig, Sebastian, Holden, Arthur L, Ahmad, Tariq
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2014)
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Journal Article
638 5-Aminosalicylate (5-ASA) Induced Nephrotoxicity in Inflammatory Bowel Disease
So, Kenji, Bewshea, Claire M, Heap, Graham A, Muller, Andrew F, Delaney, Michael P, Daneshmend, Tawfique K, Hart, Ailsa L, Orchard, Timothy R, Irving, Peter M, D'Souza, Richard, Mulgrew, Chris, Kwan, Jonathan, Silverberg, Mark S, Gearry, Richard B, Radford-Smith, Graham, Watermeyer, Gillian, D'Incà, Renata, Annese, Vito, Tsianos, Epameinondas V, Russell, Richard K, Wilson, David C, Parkes, Miles, Satsangi, Jack, Oram, Richard A, Weersma, Rinse K, Lawrance, Ian C, Holden, Arthur L, Lees, Charlie W, Ahmad, Tariq
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
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Journal Article
A 3.9-Centimorgan-Resolution Human Single-Nucleotide Polymorphism Linkage Map and Screening Set
Matise, Tara C., Sachidanandam, Ravi, Clark, Andrew G., Kruglyak, Leonid, Wijsman, Ellen, Kakol, Jerzy, Buyske, Steven, Chui, Buena, Cohen, Patrick, Toma, Claudia de, Ehm, Margaret, Glanowski, Stephen, He, Chunsheng, Heil, Jeremy, Markianos, Kyriacos, McMullen, Ivy, Pericak-Vance, Margaret A., Silbergleit, Arkadiy, Stein, Lincoln, Wagner, Michael, Wilson, Alexander F., Winick, Jeffrey D., Winn-Deen, Emily S., Yamashiro, Carl T., Cann, Howard M., Lai, Eric, Holden, Arthur L.
Published in American journal of human genetics (01.08.2003)
Published in American journal of human genetics (01.08.2003)
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Journal Article
Linkage Disequilibrium and Inference of Ancestral Recombination in 538 Single-Nucleotide Polymorphism Clusters across the Human Genome
Clark, Andrew G., Nielsen, Rasmus, Signorovitch, James, Matise, Tara C., Glanowski, Stephen, Heil, Jeremy, Winn-Deen, Emily S., Holden, Arthur L., Lai, Eric
Published in American journal of human genetics (01.08.2003)
Published in American journal of human genetics (01.08.2003)
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Journal Article
HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants
Heap, Graham A, Weedon, Michael N, Bewshea, Claire M, Singh, Abhey, Chen, Mian, Satchwell, Jack B, Vivian, Julian P, So, Kenji, Dubois, Patrick C, Andrews, Jane M, Annese, Vito, Bampton, Peter, Barnardo, Martin, Bell, Sally, Cole, Andy, Connor, Susan J, Creed, Tom, Cummings, Fraser R, D'Amato, Mauro, Daneshmend, Tawfique K, Fedorak, Richard N, Florin, Timothy H, Gaya, Daniel R, Greig, Emma, Halfvarson, Jonas, Hart, Alisa, Irving, Peter M, Jones, Gareth, Karban, Amir, Lawrance, Ian C, Lee, James C, Lees, Charlie, Lev-Tzion, Raffi, Lindsay, James O, Mansfield, John, Mawdsley, Joel, Mazhar, Zia, Parkes, Miles, Parnell, Kirstie, Orchard, Timothy R, Radford-Smith, Graham, Russell, Richard K, Reffitt, David, Satsangi, Jack, Silverberg, Mark S, Sturniolo, Giacomo C, Tremelling, Mark, Tsianos, Epameinondas V, van Heel, David A, Walsh, Alissa, Watermeyer, Gill, Weersma, Rinse K, Zeissig, Sebastian, Rossjohn, Jamie, Holden, Arthur L, Ahmad, Tariq
Published in Nature genetics (01.10.2014)
Published in Nature genetics (01.10.2014)
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Journal Article
Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles
Goldstein, Jacqueline I., Fredrik Jarskog, L., Hilliard, Chris, Alfirevic, Ana, Duncan, Laramie, Fourches, Denis, Huang, Hailiang, Lek, Monkol, Neale, Benjamin M., Ripke, Stephan, Shianna, Kevin, Szatkiewicz, Jin P., Tropsha, Alexander, van den Oord, Edwin JCG, Cascorbi, Ingolf, Dettling, Michael, Gazit, Ephraim, Goff, Donald C., Holden, Arthur L., Kelly, Deanna L., Malhotra, Anil K., Nielsen, Jimmi, Pirmohamed, Munir, Rujescu, Dan, Werge, Thomas, Levy, Deborah L., Josiassen, Richard C., Kennedy, James L., Lieberman, Jeffrey A., Daly, Mark J., Sullivan, Patrick F.
Published in Nature communications (04.09.2014)
Published in Nature communications (04.09.2014)
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Journal Article
The International Serious Adverse Events Consortium: the international Serious Adverse Events Consortium is generating novel insights into the genetics and biology of drug-induced serious adverse events, and thereby improving pharmaceutical product development and decision-making
Holden, Arthur L, Contreras, Jorge L, John, Sally, Nelson, Matthew R
Published in Nature reviews. Drug discovery (01.11.2014)
Published in Nature reviews. Drug discovery (01.11.2014)
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Journal Article
Thiopurine induced pancreatitis in inflammatory bowel disease: clinical features and genetic determinants
Heap, Graham A., Singh, Abhey, Bewshea, Claire M., Weedon, Michael, Dubois, Patrick, Andrews, Jane M., Annese, Vito, Bampton, Peter A., Bell, Sally, Cole, Andy, Connor, Susan J., Creed, Tom, D'Amato, Mauro, Fedorak, Richard N., Florin, Timothy H., Gaya, Daniel R., Greig, Emma, Halfvarson, Jonas, Irving, Peter M., Karban, Amir, Lawrance, Ian C., Lev-Tzion, Raffi, Lindsay, James O., Mawsley, Joel, Mazher, Zia, Orchard, Timothy R., Radford-Smith, Graham L., Reffitt, David, Silverberg, Mark S., Sturniolo, Giacomo C., Tsianos, Epameinondas V., Walsh, Alissa, Zeissig, Sebastian, Holden, Arthur L., Ahmad, Tariq
Published in Gastroenterology (New York, N.Y. 1943) (2014)
Published in Gastroenterology (New York, N.Y. 1943) (2014)
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