4-1BB agonism: adding the accelerator to cancer immunotherapy
Chester, Cariad, Ambulkar, Siddhant, Kohrt, Holbrook E.
Published in Cancer Immunology, Immunotherapy (01.10.2016)
Published in Cancer Immunology, Immunotherapy (01.10.2016)
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Journal Article
Book Review
Therapeutic antitumor immunity by checkpoint blockade is enhanced by ibrutinib, an inhibitor of both BTK and ITK
Sagiv-Barfi, Idit, Kohrt, Holbrook E. K., Czerwinski, Debra K., Ng, Patrick P., Chang, Betty Y., Levy, Ronald
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.2015)
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Journal Article
Rationale for anti-CD137 cancer immunotherapy
Makkouk, Amani, Chester, Cariad, Kohrt, Holbrook E
Published in European journal of cancer (1990) (01.02.2016)
Published in European journal of cancer (1990) (01.02.2016)
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Journal Article
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
Herbst, Roy S., Soria, Jean-Charles, Kowanetz, Marcin, Fine, Gregg D., Hamid, Omid, Gordon, Michael S., Sosman, Jeffery A., McDermott, David F., Powderly, John D., Gettinger, Scott N., Kohrt, Holbrook E. K., Horn, Leora, Lawrence, Donald P., Rost, Sandra, Leabman, Maya, Xiao, Yuanyuan, Mokatrin, Ahmad, Koeppen, Hartmut, Hegde, Priti S., Mellman, Ira, Chen, Daniel S., Hodi, F. Stephen
Published in Nature (London) (27.11.2014)
Published in Nature (London) (27.11.2014)
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Journal Article
Boosting Cancer Immunotherapy with Anti-CD137 Antibody Therapy
Yonezawa, Atsushi, Dutt, Suparna, Chester, Cariad, Kim, Jeewon, Kohrt, Holbrook E
Published in Clinical cancer research (15.07.2015)
Published in Clinical cancer research (15.07.2015)
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Journal Article
CD44+ Cells in Head and Neck Squamous Cell Carcinoma Suppress T-Cell-Mediated Immunity by Selective Constitutive and Inducible Expression of PD-L1
Lee, Yunqin, Shin, June Ho, Longmire, Michelle, Wang, Hua, Kohrt, Holbrook E, Chang, Howard Y, Sunwoo, John B
Published in Clinical cancer research (15.07.2016)
Published in Clinical cancer research (15.07.2016)
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Journal Article
Pembrolizumab in Relapsed and Refractory Mycosis Fungoides and Sézary Syndrome: A Multicenter Phase II Study
Khodadoust, Michael S, Rook, Alain H, Porcu, Pierluigi, Foss, Francine, Moskowitz, Alison J, Shustov, Andrei, Shanbhag, Satish, Sokol, Lubomir, Fling, Steven P, Ramchurren, Nirasha, Pierce, Robert, Davis, Asa, Shine, Richard, Li, Shufeng, Fong, Sophia, Kim, Jinah, Yang, Yi, Blumenschein, Wendy M, Yearley, Jennifer H, Das, Biswajit, Patidar, Rajesh, Datta, Vivekananda, Cantu, Erin, McCutcheon, Justine N, Karlovich, Chris, Williams, P Mickey, Subrahmanyam, Priyanka B, Maecker, Holden T, Horwitz, Steven M, Sharon, Elad, Kohrt, Holbrook E, Cheever, Martin A, Kim, Youn H
Published in Journal of clinical oncology (01.01.2020)
Published in Journal of clinical oncology (01.01.2020)
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Journal Article
A First-in-Human Phase I Study of Subcutaneous Outpatient Recombinant Human IL15 (rhIL15) in Adults with Advanced Solid Tumors
Miller, Jeffrey S, Morishima, Chihiro, McNeel, Douglas G, Patel, Manish R, Kohrt, Holbrook E K, Thompson, John A, Sondel, Paul M, Wakelee, Heather A, Disis, Mary L, Kaiser, Judith C, Cheever, Martin A, Streicher, Howard, Creekmore, Steven P, Waldmann, Thomas A, Conlon, Kevin C
Published in Clinical cancer research (01.04.2018)
Published in Clinical cancer research (01.04.2018)
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Journal Article
PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma
Nghiem, Paul T, Bhatia, Shailender, Lipson, Evan J, Kudchadkar, Ragini R, Miller, Natalie J, Annamalai, Lakshmanan, Berry, Sneha, Chartash, Elliot K, Daud, Adil, Fling, Steven P, Friedlander, Philip A, Kluger, Harriet M, Kohrt, Holbrook E, Lundgren, Lisa, Margolin, Kim, Mitchell, Alan, Olencki, Thomas, Pardoll, Drew M, Reddy, Sunil A, Shantha, Erica M, Sharfman, William H, Sharon, Elad, Shemanski, Lynn R, Shinohara, Michi M, Sunshine, Joel C, Taube, Janis M, Thompson, John A, Townson, Steven M, Yearley, Jennifer H, Topalian, Suzanne L, Cheever, Martin A
Published in The New England journal of medicine (30.06.2016)
Published in The New England journal of medicine (30.06.2016)
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Journal Article
Strategic Combinations: The Future of Oncolytic Virotherapy with Reovirus
Zhao, Xing, Chester, Cariad, Rajasekaran, Narendiran, He, ZhiXu, Kohrt, Holbrook E
Published in Molecular cancer therapeutics (01.05.2016)
Published in Molecular cancer therapeutics (01.05.2016)
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Journal Article
Assessing Immune-Related Adverse Events of Efficacious Combination Immunotherapies in Preclinical Models of Cancer
Liu, Jing, Blake, Stephen J, Harjunpää, Heidi, Fairfax, Kirsten A, Yong, Michelle C R, Allen, Stacey, Kohrt, Holbrook E, Takeda, Kazuyoshi, Smyth, Mark J, Teng, Michele W L
Published in Cancer research (Chicago, Ill.) (15.09.2016)
Published in Cancer research (Chicago, Ill.) (15.09.2016)
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Journal Article
Diffuse High Intensity PD–L1 Staining in Thymic Epithelial Tumors
Padda, Sukhmani K., Riess, Jonathan W., Schwartz, Erich J., Tian, Lu, Kohrt, Holbrook E., Neal, Joel W., West, Robert B., Wakelee, Heather A.
Published in Journal of thoracic oncology (01.03.2015)
Published in Journal of thoracic oncology (01.03.2015)
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Journal Article
Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor
Shin, June Ho, Zhang, Luhua, Murillo-Sauca, Oihana, Kim, Junmo, Kohrt, Holbrook E. K., Bui, Jack D., Sunwoo, John B.
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.2013)
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Journal Article
Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies
Kohrt, Holbrook E., Thielens, Ariane, Marabelle, Aurelien, Sagiv-Barfi, Idit, Sola, Caroline, Chanuc, Fabien, Fuseri, Nicolas, Bonnafous, Cécile, Czerwinski, Debra, Rajapaksa, Amanda, Waller, Erin, Ugolini, Sophie, Vivier, Eric, Romagné, François, Levy, Ronald, Bléry, Mathieu, André, Pascale
Published in Blood (30.01.2014)
Published in Blood (30.01.2014)
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Journal Article
Rapid development of exhaustion and down-regulation of eomesodermin limit the antitumor activity of adoptively transferred murine natural killer cells
Gill, Saar, Vasey, Adrianne E., De Souza, Alysha, Baker, Jeanette, Smith, Aaron T., Kohrt, Holbrook E., Florek, Mareike, Gibbs, Kenneth D., Tate, Keri, Ritchie, David S., Negrin, Robert S.
Published in Blood (14.06.2012)
Published in Blood (14.06.2012)
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Journal Article
Ibrutinib antagonizes rituximab-dependent NK cell–mediated cytotoxicity
Kohrt, Holbrook E., Sagiv-Barfi, Idit, Rafiq, Sarwish, Herman, Sarah E.M., Butchar, Jonathon P., Cheney, Carolyn, Zhang, Xiaoli, Buggy, Joseph J., Muthusamy, Natarajan, Levy, Ronald, Johnson, Amy J., Byrd, John C.
Published in Blood (20.03.2014)
Published in Blood (20.03.2014)
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Journal Article
CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies
Kohrt, Holbrook E., Houot, Roch, Goldstein, Matthew J., Weiskopf, Kipp, Alizadeh, Ash A., Brody, Josh, Müller, Antonia, Pachynski, Russell, Czerwinski, Debra, Coutre, Steven, Chao, Mark P., Chen, Lieping, Tedder, Thomas F., Levy, Ronald
Published in Blood (24.02.2011)
Published in Blood (24.02.2011)
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Journal Article
Acute myeloid leukaemia in the elderly: a review
Pollyea, Daniel A., Kohrt, Holbrook E., Medeiros, Bruno C.
Published in British journal of haematology (01.03.2011)
Published in British journal of haematology (01.03.2011)
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Journal Article