Iron Metabolism in the Recovery Phase of Critical Illness with a Focus on Sepsis
Zhang, Xiyang, Holbein, Bruce, Zhou, Juan, Lehmann, Christian
Published in International journal of molecular sciences (26.06.2024)
Published in International journal of molecular sciences (26.06.2024)
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Journal Article
Iron should be restricted in acute infection
Scott, Cassidy R, Holbein, Bruce E, Lehmann, Christian D
Published in Frontiers in bioscience (01.01.2020)
Published in Frontiers in bioscience (01.01.2020)
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Journal Article
Iron Sequestrant DIBI, a Potential Alternative for Nares Decolonization of Methicillin-Resistant Staphylococcus aureus, Is Anti-infective and Inhibitory for Mupirocin-Resistant Isolates
Allan, David S, Parquet, Maria Del Carmen, Savage, Kimberley A, Holbein, Bruce E
Published in Antimicrobial agents and chemotherapy (21.02.2020)
Published in Antimicrobial agents and chemotherapy (21.02.2020)
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Journal Article
Comparison of Treatment Effects of Different Iron Chelators in Experimental Models of Sepsis
Lehmann, Christian, Aali, Maral, Zhou, Juan, Holbein, Bruce
Published in Life (Basel, Switzerland) (14.01.2021)
Published in Life (Basel, Switzerland) (14.01.2021)
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Journal Article
Iron Chelation as a Potential Therapeutic Approach in Acute Lung Injury
Zhang, Xiyang, Zhou, Juan, Holbein, Bruce E, Lehmann, Christian
Published in Life (Basel, Switzerland) (01.07.2023)
Published in Life (Basel, Switzerland) (01.07.2023)
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Journal Article
Anti-Inflammatory Effects of the Iron Chelator, DIBI, in Experimental Acute Lung Injury
Lehmann, Christian, Alizadeh-Tabrizi, Nazli, Hall, Stefan, Faridi, Sufyan, Euodia, Irene, Holbein, Bruce, Zhou, Juan, Chappe, Valerie
Published in Molecules (Basel, Switzerland) (23.06.2022)
Published in Molecules (Basel, Switzerland) (23.06.2022)
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Journal Article
Novel Iron-Chelator DIBI Inhibits Staphylococcus aureus Growth, Suppresses Experimental MRSA Infection in Mice and Enhances the Activities of Diverse Antibiotics in vitro
Parquet, Maria Del Carmen, Savage, Kimberley A, Allan, David S, Davidson, Ross J, Holbein, Bruce E
Published in Frontiers in microbiology (14.08.2018)
Published in Frontiers in microbiology (14.08.2018)
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Journal Article
Iron Restriction to Clinical Isolates of Candida albicans by the Novel Chelator DIBI Inhibits Growth and Increases Sensitivity to Azoles In Vitro and In Vivo in a Murine Model of Experimental Vaginitis
Savage, Kimberley A, Parquet, Maria del Carmen, Allan, David S, Davidson, Ross J, Holbein, Bruce E, Lilly, Elizabeth A, Fidel, Jr, Paul L
Published in Antimicrobial agents and chemotherapy (01.08.2018)
Published in Antimicrobial agents and chemotherapy (01.08.2018)
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Journal Article
Antibiotic-Resistant Acinetobacter baumannii Is Susceptible to the Novel Iron-Sequestering Anti-infective DIBI In Vitro and in Experimental Pneumonia in Mice
Parquet, Maria Del Carmen, Savage, Kimberley A, Allan, David S, Ang, M Trisha C, Chen, Wangxue, Logan, Susan M, Holbein, Bruce E
Published in Antimicrobial agents and chemotherapy (01.09.2019)
Published in Antimicrobial agents and chemotherapy (01.09.2019)
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Journal Article
Anti-inflammatory and anti-bacterial effects of iron chelation in experimental sepsis
Islam, Sufia, PhD, Jarosch, Stefan, DEAA, Zhou, Juan, MD, PhD, Parquet, Maria del Carmen, PhD, Toguri, James Thomas, BSc, Colp, Patricia, Holbein, Bruce E., PhD, Lehmann, Christian, MD, PhD, FRCPC
Published in The Journal of surgical research (01.01.2016)
Published in The Journal of surgical research (01.01.2016)
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Journal Article
Selective sensitivity of the gut microbiome to iron chelators in polybacterial abdominal sepsis
Dickson, Kayle, Liu, Simo, Zhou, Juan, Langille, Morgan, Holbein, Bruce E., Lehmann, Christian
Published in Medical hypotheses (01.11.2018)
Published in Medical hypotheses (01.11.2018)
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Journal Article
Iron-withdrawing anti-infectives for new host-directed therapies based on iron dependence, the Achilles’ heel of antibiotic-resistant microbes
Holbein, Bruce E., Ang, M. Trisha C., Allan, David S., Chen, Wangxue, Lehmann, Christian
Published in Environmental chemistry letters (01.08.2021)
Published in Environmental chemistry letters (01.08.2021)
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Journal Article
Enhanced Fe3+ binding through cooperativity of 3-hydroxypyridin-4-one groups within a linear co-polymer: wrapping effect leading to superior antimicrobial activity
Gumbau-Brisa, Roger, Ang, M. Trisha C., Holbein, Bruce E., Bierenstiel, Matthias
Published in Biometals (01.12.2020)
Published in Biometals (01.12.2020)
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Journal Article
Iron chelation for the treatment of uveitis
Chen, Junru, Zhou, Juan, Kelly, Mel, Holbein, Bruce E, Lehmann, Christian
Published in Medical hypotheses (01.06.2017)
Published in Medical hypotheses (01.06.2017)
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Journal Article
DIBI, a novel 3-hydroxypyridin-4-one chelator iron-binding polymer, inhibits breast cancer cell growth and functions as a chemosensitizer by promoting S-phase DNA damage
Greenshields, Anna L., Power Coombs, Melanie R., Fernando, Wasundara, Holbein, Bruce E., Hoskin, David W.
Published in Biometals (01.12.2019)
Published in Biometals (01.12.2019)
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Journal Article
Antimicrobial Activity of the Iron-Chelator, DIBI, against Multidrug-Resistant Canine Methicillin-Susceptible Staphylococcus pseudintermedius: A Preliminary Study of Four Clinical Strains
Nocera, Francesca Paola, Iovane, Giuseppe, De Martino, Luisa, Holbein, Bruce E.
Published in Pathogens (Basel) (07.06.2022)
Published in Pathogens (Basel) (07.06.2022)
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Journal Article