Phenotypic plasticity and the evolution of azole resistance in Aspergillus fumigatus; an expression profile of clinical isolates upon exposure to itraconazole
Hokken, Margriet W J, Zoll, Jan, Coolen, Jordy P M, Zwaan, Bas J, Verweij, Paul E, Melchers, Willem J G
Published in BMC genomics (09.01.2019)
Published in BMC genomics (09.01.2019)
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Molecular species selectivity of lipid transport creates a mitochondrial sink for di‐unsaturated phospholipids
Renne, Mike F, Bao, Xue, Hokken, Margriet WJ, Bierhuizen, Adolf S, Hermansson, Martin, Sprenger, Richard R, Ewing, Tom A, Ma, Xiao, Cox, Ruud C, Brouwers, Jos F, De Smet, Cedric H, Ejsing, Christer S, de Kroon, Anton IPM
Published in The EMBO journal (17.01.2022)
Published in The EMBO journal (17.01.2022)
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Journal Article
The Transcriptome Response to Azole Compounds in Aspergillus fumigatus Shows Differential Gene Expression across Pathways Essential for Azole Resistance and Cell Survival
Hokken, Margriet, Coolen, Jordy, Steenbreker, Hilbert, Zoll, Jan, Baltussen, Tim, Verweij, Paul, Melchers, Willem
Published in Journal of fungi (Basel) (30.07.2023)
Published in Journal of fungi (Basel) (30.07.2023)
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Journal Article
Facilitators of adaptation and antifungal resistance mechanisms in clinically relevant fungi
Hokken, Margriet W.J., Zwaan, B.J., Melchers, W.J.G., Verweij, P.E.
Published in Fungal genetics and biology (01.11.2019)
Published in Fungal genetics and biology (01.11.2019)
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Journal Article
Resistance profiling of Aspergillus fumigatus to olorofim indicates absence of intrinsic resistance and unveils the molecular mechanisms of acquired olorofim resistance
Buil, Jochem B., Oliver, Jason D., Law, Derek, Baltussen, Tim, Zoll, Jan, Hokken, Margriet W. J., Tehupeiory-Kooreman, Marlou, Melchers, Willem J. G., Birch, Mike, Verweij, Paul E.
Published in Emerging microbes & infections (31.12.2022)
Published in Emerging microbes & infections (31.12.2022)
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Journal Article
Hmg1 Gene Mutation Prevalence in Triazole-Resistant Aspergillus fumigatus Clinical Isolates
Resendiz-Sharpe, Agustin, Hokken, Margriet W.J., Mercier, Toine, Merckx, Rita, Verhagen, Kamiel, Dewitte, Lisa, Melchers, Willem J.G., Verweij, Paul E., Maertens, Johan, Lagrou, Katrien
Published in Journal of fungi (Basel) (16.10.2020)
Published in Journal of fungi (Basel) (16.10.2020)
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Journal Article
The Transcriptome Response to Azole Compounds in IAspergillus fumigatus/I Shows Differential Gene Expression across Pathways Essential for Azole Resistance and Cell Survival
Hokken, Margriet W. J, Coolen, Jordy P. M, Steenbreker, Hilbert, Zoll, Jan, Baltussen, Tim J. H, Verweij, Paul E, Melchers, Willem J. G
Published in Journal of fungi (Basel) (01.07.2023)
Published in Journal of fungi (Basel) (01.07.2023)
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Journal Article