Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination
Nemes, Elisa, Geldenhuys, Hennie, Rozot, Virginie, Rutkowski, Kathryn T, Ratangee, Frances, Bilek, Nicole, Mabwe, Simbarashe, Makhethe, Lebohang, Erasmus, Mzwandile, Toefy, Asma, Mulenga, Humphrey, Hanekom, Willem A, Self, Steven G, Bekker, Linda-Gail, Ryall, Robert, Gurunathan, Sanjay, DiazGranados, Carlos A, Andersen, Peter, Kromann, Ingrid, Evans, Thomas, Ellis, Ruth D, Landry, Bernard, Hokey, David A, Hopkins, Robert, Ginsberg, Ann M, Scriba, Thomas J, Hatherill, Mark
Published in The New England journal of medicine (12.07.2018)
Published in The New England journal of medicine (12.07.2018)
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Safety and immunogenicity of an inactivated whole cell tuberculosis vaccine booster in adults primed with BCG: A randomized, controlled trial of DAR-901
von Reyn, C Fordham, Lahey, Timothy, Arbeit, Robert D, Landry, Bernard, Kailani, Leway, Adams, Lisa V, Haynes, Brenda C, Mackenzie, Todd, Wieland-Alter, Wendy, Connor, Ruth I, Tvaroha, Sue, Hokey, David A, Ginsberg, Ann M, Waddell, Richard
Published in PloS one (12.05.2017)
Published in PloS one (12.05.2017)
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CD4+ T cell cytokine responses to the DAR-901 booster vaccine in BCG-primed adults: A randomized, placebo-controlled trial
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Published in PloS one (23.05.2019)
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A Phase I, Open-Label Trial, Evaluating the Safety and Immunogenicity of Candidate Tuberculosis Vaccines AERAS-402 and MVA85A, Administered by Prime-Boost Regime in BCG-Vaccinated Healthy Adults
Sheehan, Sharon, Harris, Stephanie A, Satti, Iman, Hokey, David A, Dheenadhayalan, Veerabadran, Stockdale, Lisa, Manjaly Thomas, Zita-Rose, Minhinnick, Alice, Wilkie, Morven, Vermaak, Samantha, Meyer, Joel, O'Shea, Matthew K, Pau, Maria Grazia, Versteege, Isabella, Douoguih, Macaya, Hendriks, Jenny, Sadoff, Jerald, Landry, Bernard, Moss, Paul, McShane, Helen
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Published in PloS one (03.11.2015)
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A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis -specific T-cell responses in human
van Dissel, Jaap T, Joosten, Simone A, Hoff, Søren T, Soonawala, Darius, Prins, Corine, Hokey, David A, O’Dee, Dawn M, Graves, Andrew, Thierry-Carstensen, Birgit, Andreasen, Lars V, Ruhwald, Morten, de Visser, Adriëtte W, Agger, Else Marie, Ottenhoff, Tom H.M, Kromann, Ingrid, Andersen, Peter
Published in Vaccine (12.12.2014)
Published in Vaccine (12.12.2014)
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Dose Optimization of H56:IC31 Vaccine for Tuberculosis-Endemic Populations. A Double-Blind, Placebo-controlled, Dose-Selection Trial
Suliman, Sara, Luabeya, Angelique Kany Kany, Geldenhuys, Hennie, Tameris, Michele, Hoff, Soren T, Shi, Zhongkai, Tait, Dereck, Kromann, Ingrid, Ruhwald, Morten, Rutkowski, Kathryn Tucker, Shepherd, Barbara, Hokey, David, Ginsberg, Ann M, Hanekom, Willem A, Andersen, Peter, Scriba, Thomas J, Hatherill, Mark
Published in American journal of respiratory and critical care medicine (15.01.2019)
Published in American journal of respiratory and critical care medicine (15.01.2019)
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Aerosol vaccination with AERAS-402 elicits robust cellular immune responses in the lungs of rhesus macaques but fails to protect against high-dose Mycobacterium tuberculosis challenge
Darrah, Patricia A, Bolton, Diane L, Lackner, Andrew A, Kaushal, Deepak, Aye, Pyone Pyone, Mehra, Smriti, Blanchard, James L, Didier, Peter J, Roy, Chad J, Rao, Srinivas S, Hokey, David A, Scanga, Charles A, Sizemore, Donata R, Sadoff, Jerald C, Roederer, Mario, Seder, Robert A
Published in The Journal of immunology (1950) (15.08.2014)
Published in The Journal of immunology (1950) (15.08.2014)
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A 2-Dose AERAS-402 Regimen Boosts CD8+ Polyfunctionality in HIV-Negative, BCG-Vaccinated Recipients
Sivakumaran, Dhanasekaran, Blatner, Gretta, Bakken, Rasmus, Hokey, David, Ritz, Christian, Jenum, Synne, Grewal, Harleen M. S.
Published in Frontiers in immunology (11.06.2021)
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Induction of antitumor immunity in vivo following delivery of a novel HPV-16 DNA vaccine encoding an E6/E7 fusion antigen
Yan, Jian, Reichenbach, Dawn K, Corbitt, Natasha, Hokey, David A, Ramanathan, Mathura P, McKinney, Kibwei A, Weiner, David B, Sewell, Duane
Published in Vaccine (14.01.2009)
Published in Vaccine (14.01.2009)
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Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques
Hirao, Lauren A, Wu, Ling, Khan, Amir S, Hokey, David A, Yan, Jian, Dai, Anlan, Betts, Michael R, Draghia-Akli, Ruxandra, Weiner, David B
Published in Vaccine (13.06.2008)
Published in Vaccine (13.06.2008)
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The Cross-Species Mycobacterial Growth Inhibition Assay (MGIA) Project, 2010-2014
Brennan, Michael J, Tanner, Rachel, Morris, Sheldon, Scriba, Thomas J, Achkar, Jacqueline M, Zelmer, Andrea, Hokey, David A, Izzo, Angelo, Sharpe, Sally, Williams, Ann, Penn-Nicholson, Adam, Erasmus, Mzwandile, Stylianou, Elena, Hoft, Daniel F, McShane, Helen, Fletcher, Helen A
Published in Clinical and vaccine immunology (01.09.2017)
Published in Clinical and vaccine immunology (01.09.2017)
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A new tool for tuberculosis vaccine screening: Ex vivo Mycobacterial Growth Inhibition Assay indicates BCG-mediated protection in a murine model of tuberculosis
Zelmer, Andrea, Tanner, Rachel, Stylianou, Elena, Damelang, Timon, Morris, Sheldon, Izzo, Angelo, Williams, Ann, Sharpe, Sally, Pepponi, Ilaria, Walker, Barry, Hokey, David A, McShane, Helen, Brennan, Michael, Fletcher, Helen
Published in BMC infectious diseases (12.08.2016)
Published in BMC infectious diseases (12.08.2016)
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Safety and Immunogenicity of Adenovirus 35 Tuberculosis Vaccine Candidate in Adults with Active or Previous Tuberculosis. A Randomized Trial
van Zyl-Smit, Richard N, Esmail, Aliasgar, Bateman, Mary E, Dawson, Rodney, Goldin, Jonathan, van Rikxoort, Eva, Douoguih, Macaya, Pau, Maria Grazia, Sadoff, Jerald C, McClain, J Bruce, Snowden, Margaret Ann, Benko, Jacqueline, Hokey, David A, Rutkowski, Kathryn Tucker, Graves, Andrew, Shepherd, Barbara, Ishmukhamedov, Sadritdin, Kagina, Benjamin M N, Abel, Brian, Hanekom, Willem A, Scriba, Thomas J, Bateman, Eric D
Published in American journal of respiratory and critical care medicine (01.05.2017)
Published in American journal of respiratory and critical care medicine (01.05.2017)
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Immunostimulation of dendritic cells by cationic liposomes
Vangasseri, Dileep P., Cui, Zhengrong, Chen, Weihsu, Hokey, David A., Falo, Louis D., Huang, Leaf
Published in Molecular membrane biology (01.09.2006)
Published in Molecular membrane biology (01.09.2006)
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The novel tuberculosis vaccine, AERAS-402, is safe in healthy infants previously vaccinated with BCG, and induces dose-dependent CD4 and CD8T cell responses
Kagina, Benjamin M.N, Tameris, Michele D, Geldenhuys, Hennie, Hatherill, Mark, Abel, Brian, Hussey, Gregory D, Scriba, Thomas J, Mahomed, Hassan, Sadoff, Jerald C, Hanekom, Willem A
Published in Vaccine (14.10.2014)
Published in Vaccine (14.10.2014)
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The frequencies of IFNγ+IL2+TNFα+ PPD-specific CD4+CD45RO+ T-cells correlate with the magnitude of the QuantiFERON® gold in-tube response in a prospective study of healthy indian adolescents
Jenum, Synne, Grewal, Harleen M S, Hokey, David A, Kenneth, John, Vaz, Mario, Doherty, Timothy Mark, Jahnsen, Frode Lars
Published in PloS one (2014)
Published in PloS one (2014)
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OMIP‐022: Comprehensive assessment of antigen‐specific human T‐cell functionality and memory
Graves, Andrew J., Padilla, Marcelino G., Hokey, David A.
Published in Cytometry. Part A (01.07.2014)
Published in Cytometry. Part A (01.07.2014)
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