Evidence That the Adenovirus Single-Stranded DNA Binding Protein Mediates the Assembly of Biomolecular Condensates to Form Viral Replication Compartments
Hidalgo, Paloma, Pimentel, Arturo, Mojica-Santamaría, Diana, von Stromberg, Konstantin, Hofmann-Sieber, Helga, Lona-Arrona, Christian, Dobner, Thomas, González, Ramón A
Published in Viruses (06.09.2021)
Published in Viruses (06.09.2021)
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Human Adenovirus Type 5 Infection Leads to Nuclear Envelope Destabilization and Membrane Permeability Independently of Adenovirus Death Protein
Pfitzner, Søren, Bosse, Jens B, Hofmann-Sieber, Helga, Flomm, Felix, Reimer, Rudolph, Dobner, Thomas, Grünewald, Kay, Franken, Linda E
Published in International journal of molecular sciences (02.12.2021)
Published in International journal of molecular sciences (02.12.2021)
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Protein-Protein Interactions Facilitate E4orf6-Dependent Regulation of E1B-55K SUMOylation in HAdV-C5 Infection
Fiedler, Marie, Ip, Wing-Hang, Hofmann-Sieber, Helga, Wilkens, Britta, Nkrumah, Francis K, Zhang, Wenli, Ehrhardt, Anja, Bertzbach, Luca D, Dobner, Thomas
Published in Viruses (24.02.2022)
Published in Viruses (24.02.2022)
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Efficient Transformation of Primary Human Mesenchymal Stromal Cells by Adenovirus Early Region 1 Oncogenes
Speiseder, Thomas, Hofmann-Sieber, Helga, Rodríguez, Estefanía, Schellenberg, Anna, Akyüz, Nuray, Dierlamm, Judith, Spruss, Thilo, Lange, Claudia, Dobner, Thomas
Published in Journal of virology (01.01.2017)
Published in Journal of virology (01.01.2017)
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Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice
Hauber, Ilona, Hofmann-Sieber, Helga, Chemnitz, Jan, Dubrau, Danilo, Chusainow, Janet, Stucka, Rolf, Hartjen, Philip, Schambach, Axel, Ziegler, Patrick, Hackmann, Karl, Schröck, Evelin, Schumacher, Udo, Lindner, Christoph, Grundhoff, Adam, Baum, Christopher, Manz, Markus G, Buchholz, Frank, Hauber, Joachim
Published in PLoS pathogens (01.09.2013)
Published in PLoS pathogens (01.09.2013)
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Engineering of a target site-specific recombinase by a combined evolution- and structure-guided approach
Abi-Ghanem, Josephine, Chusainow, Janet, Karimova, Madina, Spiegel, Christopher, Hofmann-Sieber, Helga, Hauber, Joachim, Buchholz, Frank, Pisabarro, M Teresa
Published in Nucleic acids research (01.02.2013)
Published in Nucleic acids research (01.02.2013)
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Excision of HIV-1 proviral DNA by recombinant cell permeable tre-recombinase
Mariyanna, Lakshmikanth, Priyadarshini, Poornima, Hofmann-Sieber, Helga, Krepstakies, Marcel, Walz, Nicole, Grundhoff, Adam, Buchholz, Frank, Hildt, Eberhard, Hauber, Joachim
Published in PloS one (13.02.2012)
Published in PloS one (13.02.2012)
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Isolation and initial propagation of guinea pig adenovirus (GPAdV) in Cavia porcellus cell lines [version 2; peer review: 2 approved]
Kajon, Adriana E, Li, Xiaoxin, Gonzalez, Gabriel, Core, Susan, Hofmann-Sieber, Helga, Leng, Shuguang
Published in F1000 research (01.01.2019)
Published in F1000 research (01.01.2019)
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Impact of ETIF Deletion on Safety and Immunogenicity of Equine Herpesvirus Type 1-Vectored Vaccines
Helga Hofmann-Sieber, Jens Wild, Nicole Fiedler, Karsten Tischer, Jens von Einem, Nikolaus Osterrieder, Heike Hofmann, Josef Köstler, Ralf Wagner
Published in Journal of Virology (01.11.2010)
Published in Journal of Virology (01.11.2010)
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Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity
Karpinski, Janet, Hauber, Ilona, Chemnitz, Jan, Schäfer, Carola, Paszkowski-Rogacz, Maciej, Chakraborty, Deboyoti, Beschorner, Niklas, Hofmann-Sieber, Helga, Lange, Ulrike C, Grundhoff, Adam, Hackmann, Karl, Schrock, Evelin, Abi-Ghanem, Josephine, Pisabarro, M Teresa, Surendranath, Vineeth, Schambach, Axel, Lindner, Christoph, van Lunzen, Jan, Hauber, Joachim, Buchholz, Frank
Published in Nature biotechnology (01.04.2016)
Published in Nature biotechnology (01.04.2016)
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Isolation and initial propagation of guinea pig adenovirus (GPAdV) in Cavia porcellus cell lines [version 1; peer review: 1 approved, 1 approved with reservations]
Kajon, Adriana E., Li, Xiaoxin, Gonzalez, Gabriel, Core, Susan, Hofmann-Sieber, Helga, Leng, Shuguang
Published in F1000 research (2019)
Published in F1000 research (2019)
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Patient-adapted, specific activation of HIV-1 by customized TAL effectors (TALEs), a proof of principle study
Geissler, Rene, Hauber, Ilona, Funk, Nancy, Richter, Annekatrin, Behrens, Martina, Renner, Ivonne, Chemnitz, Jan, Hofmann-Sieber, Helga, Baum, Heidi, van Lunzen, Jan, Boch, Jens, Hauber, Joachim, Behrens, Sven-Erik
Published in Virology (New York, N.Y.) (01.12.2015)
Published in Virology (New York, N.Y.) (01.12.2015)
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KIR3DS1 directs NK cell-mediated protection against human adenovirus infections
Jung, Johannes M, Ching, Wilhelm, Baumdick, Martin E, Hofmann-Sieber, Helga, Bosse, Jens B, Koyro, Tobias, Möller, Kimberly J, Wegner, Lucy, Niehrs, Annika, Russu, Kristina, Ohms, Mareike, Zhang, Wenli, Ehrhardt, Anja, Duisters, Kevin, Spierings, Eric, Hölzemer, Angelique, Körner, Christian, Jansen, Suze A, Peine, Sven, Königs, Ingo, Lütgehetmann, Marc, Perez, Daniel, Reinshagen, Konrad, Lindemans, Caroline A, Altfeld, Marcus, Belderbos, Mirjam, Dobner, Thomas, Bunders, Madeleine J
Published in Science immunology (17.09.2021)
Published in Science immunology (17.09.2021)
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Next-generation LTR-specific Tre-recombinase targets a majority of HIV-1 isolates
Hauber, Joachim, Karpinski, Janet, Hauber, Ilona, Chemnitz, Jan, Hofmann-Sieber, Helga, Nagel, Claus-Henning, Beschorner, Niklas, Schäfer, Carola, Buchholz, Frank
Published in BMC infectious diseases (23.05.2014)
Published in BMC infectious diseases (23.05.2014)
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Highly Significant Antiviral Activity of HIV-1 LTR-Specific Tre-Recombinase in Humanized Mice: e1003587
Hauber, Ilona, Hofmann-Sieber, Helga, Chemnitz, Jan, Dubrau, Danilo, Chusainow, Janet, Stucka, Rolf, Hartjen, Philip, Schambach, Axel, Ziegler, Patrick, Hackmann, Karl, Schröck, Evelin, Schumacher, Udo, Lindner, Christoph, Grundhoff, Adam, Baum, Christopher, Manz, Markus G, Buchholz, Frank, Hauber, Joachim
Published in PLoS pathogens (01.09.2013)
Published in PLoS pathogens (01.09.2013)
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Journal Article
Excision of HIV-1 Proviral DNA using Tre-Recombinase: An Experimental Update
Chemnitz, Jan, Ziegler, Patrick, Hauber, Ilona, Nagel, Claus-Henning, Hofmann-Sieber, Helga, Manz, Markus, Buchholz, Frank, Hauber, Joachim
Published in Antiviral research (01.04.2010)
Published in Antiviral research (01.04.2010)
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