Primary Endothelial Damage Is the Mechanism of Cardiotoxicity of Tubulin-Binding Drugs
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Published in Toxicological sciences (01.09.2010)
Published in Toxicological sciences (01.09.2010)
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Mechanisms underlying off-target effects of the cholesteryl ester transfer protein inhibitor torcetrapib involve L-type calcium channels
Clerc, Roger G, Stauffer, Andrea, Weibel, Franziska, Hainaut, Emmanuelle, Perez, Anne, Hoflack, Jean-Christophe, Bénardeau, Agnès, Pflieger, Philippe, Garriz, Jose Mr, Funder, John W, Capponi, Alessandro M, Niesor, Eric J
Published in Journal of hypertension (01.08.2010)
Published in Journal of hypertension (01.08.2010)
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Characterization and Interlaboratory Comparison of a Gene Expression Signature for Differentiating Genotoxic Mechanisms
Ellinger-Ziegelbauer, Heidrun, Fostel, Jennifer M., Aruga, Chinami, Bauer, Daniel, Boitier, Eric, Deng, Shibing, Dickinson, Donna, Le Fevre, Anne-Celine, Fornace, Albert J., Grenet, Olivier, Gu, Yizhong, Hoflack, Jean-Christophe, Shiiyama, Masako, Smith, Roger, Snyder, Ronald D., Spire, Catherine, Tanaka, Gotaro, Aubrecht, Jiri
Published in Toxicological sciences (01.08.2009)
Published in Toxicological sciences (01.08.2009)
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HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model
Melo, Esther, Oertle, Philipp, Trepp, Carolyn, Meistermann, Hélène, Burgoyne, Thomas, Sborgi, Lorenzo, Cabrera, Alvaro Cortes, Chen, Chia-yi, Hoflack, Jean-Christophe, Kam-Thong, Tony, Schmucki, Roland, Badi, Laura, Flint, Nicholas, Ghiani, Zeynep Eren, Delobel, Fréderic, Stucki, Corinne, Gromo, Giulia, Einhaus, Alfred, Hornsperger, Benoit, Golling, Sabrina, Siebourg-Polster, Juliane, Gerber, Francoise, Bohrmann, Bernd, Futter, Clare, Dunkley, Tom, Hiller, Sebastian, Schilling, Oliver, Enzmann, Volker, Fauser, Sascha, Plodinec, Marija, Iacone, Roberto
Published in EBioMedicine (01.01.2018)
Published in EBioMedicine (01.01.2018)
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A novel orally available small molecule that inhibits hepatitis B virus expression
Mueller, Henrik, Wildum, Steffen, Luangsay, Souphalone, Walther, Johanna, Lopez, Anaïs, Tropberger, Philipp, Ottaviani, Giorgio, Lu, Wenzhe, Parrott, Neil John, Zhang, Jitao David, Schmucki, Roland, Racek, Tomas, Hoflack, Jean-Christophe, Kueng, Erich, Point, Floriane, Zhou, Xue, Steiner, Guido, Lütgehetmann, Marc, Rapp, Gianna, Volz, Tassilo, Dandri, Maura, Yang, Song, Young, John A.T., Javanbakht, Hassan
Published in Journal of hepatology (01.03.2018)
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Disease Modeling and Phenotypic Drug Screening for Diabetic Cardiomyopathy using Human Induced Pluripotent Stem Cells
Drawnel, Faye M., Boccardo, Stefano, Prummer, Michael, Delobel, Frédéric, Graff, Alexandra, Weber, Michael, Gérard, Régine, Badi, Laura, Kam-Thong, Tony, Bu, Lei, Jiang, Xin, Hoflack, Jean-Christophe, Kiialainen, Anna, Jeworutzki, Elena, Aoyama, Natsuyo, Carlson, Coby, Burcin, Mark, Gromo, Gianni, Boehringer, Markus, Stahlberg, Henning, Hall, Benjamin J., Magnone, Maria Chiara, Kolaja, Kyle, Chien, Kenneth R., Bailly, Jacques, Iacone, Roberto
Published in Cell reports (Cambridge) (06.11.2014)
Published in Cell reports (Cambridge) (06.11.2014)
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Comparison of Coumarin-Induced Toxicity between Sandwich-Cultured Primary Rat Hepatocytes and Rats in Vivo: A Toxicogenomics Approach
KIENHUIS, Anne S, WORTELBOER, Heleen M, HOFLACK, Jean-Christophe, MOONEN, Edwin J, KLEINJANS, Jos C. S, VAN OMMEN, Ben, VAN DELFT, Joost H. M, STIERUM, Rob H
Published in Drug metabolism and disposition (01.12.2006)
Published in Drug metabolism and disposition (01.12.2006)
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Drug-induced Obstructive and Retrograde Nephropathy Associated with α2u-globulin in Male Rats
Jacobsen, Björn, Freichel, Christian, Eichinger-Chapelon, Anne, Brink, Andreas, Hoflack, Jean-Christophe, Albassam, Mudher, Lenz, Barbara
Published in Toxicologic pathology (01.02.2019)
Published in Toxicologic pathology (01.02.2019)
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Combining In Vivo and Organotypic In Vitro Approaches to Assess the Human Relevance of Basimglurant (RG7090), a Potential CAR Activator
Nudischer, Ramona, Renggli, Kasper, Bertinetti-Lapatki, Cristina, Hoflack, Jean-Christophe, Flint, Nicholas, Sewing, Sabine, Pedersen, Lykke, Schadt, Simone, Higgins, Larry G, Vardy, Audrey, Lenz, Barbara, Gand, Laurent, Boess, Franziska, Elcombe, Barbara M, Hierlemann, Andreas, Roth, Adrian B
Published in Toxicological sciences (01.08.2020)
Published in Toxicological sciences (01.08.2020)
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Epithelial cells as active player in fibrosis: findings from an in vitro model
Moll, Solange, Ebeling, Martin, Weibel, Franziska, Farina, Annarita, Araujo Del Rosario, Andrea, Hoflack, Jean Christophe, Pomposiello, Silvia, Prunotto, Marco
Published in PloS one (14.02.2013)
Published in PloS one (14.02.2013)
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Characterization of post-surgical alterations in the bile duct-cannulated rat
Bachir-Cherif, Dalila, Blum, Denise, Braendli-Baiocco, Annamaria, Chaput, Evelyne, Duran Pacheco, Gonzalo Christiano, Flint, Nicholas, Haiker, Monika, Hoflack, Jean-Christophe, Justies, Nicole, Neff, Rachel, Starke, Volkmar, Steiner, Guido, Tournillac, Charles Alexandre, Singer, Thomas, Ubeaud-Séquier, Geneviève, Schuler, Franz
Published in Xenobiotica (01.08.2011)
Published in Xenobiotica (01.08.2011)
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RTEL1의 발현을 조절하기 위한 올리고뉴클레오티드
WALLIER ANGELINA, TROPBERGER PHILIPP, BERRERA MARCO, KAMMLER SUSANNE, LEONARD BRIAN, FELBER JOSEPHINE, TRIYATNI MIRIAM, KAM THONG TONY, HOFLACK JEAN CHRISTOPHE, ZHANG JITAO DAVID, PEDERSEN LYKKE, TURLEY DANIEL JEREMY
Year of Publication 25.03.2021
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Year of Publication 25.03.2021
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Characterization of anti-peptide antibodies directed towards the automodification domain and apoptotic fragment of poly(ADP-ribose) polymerase
Duriez, Patrick J, Desnoyers, Serge, Hoflack, Jean-Christophe, Shah, Girish M, Morelle, Bruno, Bourassa, Sylvie, Poirier, Guy G, Talbot, Brian
Published in Biochimica et biophysica acta (11.02.1997)
Published in Biochimica et biophysica acta (11.02.1997)
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A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection
Bosch, Miriam, Kallin, Nina, Donakonda, Sainitin, Zhang, Jitao David, Wintersteller, Hannah, Hegenbarth, Silke, Heim, Kathrin, Ramirez, Carlos, Fürst, Anna, Lattouf, Elias Isaac, Feuerherd, Martin, Chattopadhyay, Sutirtha, Kumpesa, Nadine, Griesser, Vera, Hoflack, Jean-Christophe, Siebourg-Polster, Juliane, Mogler, Carolin, Swadling, Leo, Pallett, Laura J., Meiser, Philippa, Manske, Katrin, de Almeida, Gustavo P., Kosinska, Anna D., Sandu, Ioana, Schneider, Annika, Steinbacher, Vincent, Teng, Yan, Schnabel, Julia, Theis, Fabian, Gehring, Adam J., Boonstra, Andre, Janssen, Harry L. A., Vandenbosch, Michiel, Cuypers, Eva, Öllinger, Rupert, Engleitner, Thomas, Rad, Roland, Steiger, Katja, Oxenius, Annette, Lo, Wan-Lin, Klepsch, Victoria, Baier, Gottfried, Holzmann, Bernhard, Maini, Mala K., Heeren, Ron, Murray, Peter J., Thimme, Robert, Herrmann, Carl, Protzer, Ulrike, Böttcher, Jan P., Zehn, Dietmar, Wohlleber, Dirk, Lauer, Georg M., Hofmann, Maike, Luangsay, Souphalone, Knolle, Percy A.
Published in Nature (London) (25.07.2024)
Published in Nature (London) (25.07.2024)
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Cardiac spheroid co-cultures as a novel in vitro model to study human heart microenvironment
Polonchuk, Liudmila, Chabria, Mamta, Badi, Laura, Hoflack, Jean-Christophe, Davies, Michael J., Figtree, Gemma, Gentile, Carmine
Published in Journal of pharmacological and toxicological methods (01.09.2018)
Published in Journal of pharmacological and toxicological methods (01.09.2018)
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Tailoring in silico model to electrophysiology of individual iPSC-derived cardiomyocyte lines: One-size fits all?
Lei, Chon Lok, Wang, Ken, Gissinger, Evgenia, Flint, Nicholas, Mamta, Chabria, Badi, Laura, Hoflack, Jean-Christophe, Schuler, Franz, Lave, Thierry, Singer, Thomas, Clerx, Michael, Gavaghan, David, Mirams, Gary, Polonchuk, Liudmila
Published in Journal of pharmacological and toxicological methods (01.09.2018)
Published in Journal of pharmacological and toxicological methods (01.09.2018)
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How much of a cardiomyocyte can we get from stem cells? Setting up metrics for cardiac cell models
Chabria, Mamta, Hoflack, Jean-Christophe, Badi, Laura, Flint, Nicholas, Burcin, Mark, Graf, Martin, Singer, Thomas, Alvarez-Sanchez, Ruben, Schuler, Franz, Polonchuk, Liudmila
Published in Journal of pharmacological and toxicological methods (01.09.2016)
Published in Journal of pharmacological and toxicological methods (01.09.2016)
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