EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma
Struve, Nina, Binder, Zev A., Stead, Lucy F., Brend, Tim, Bagley, Stephen J., Faulkner, Claire, Ott, Leonie, Müller-Goebel, Justus, Weik, Anna-Sophie, Hoffer, Konstantin, Krug, Leonie, Rieckmann, Thorsten, Bußmann, Lara, Henze, Marvin, Morrissette, Jennifer J. D., Kurian, Kathreena M., Schüller, Ulrich, Petersen, Cordula, Rothkamm, Kai, O´ Rourke, Donald M., Short, Susan C., Kriegs, Malte
Published in Oncogene (09.04.2020)
Published in Oncogene (09.04.2020)
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Journal Article
Analyzing expression and phosphorylation of the EGF receptor in HNSCC
Kriegs, Malte, Clauditz, Till Sebastian, Hoffer, Konstantin, Bartels, Joanna, Buhs, Sophia, Gerull, Helwe, Zech, Henrike Barbara, Bußmann, Lara, Struve, Nina, Rieckmann, Thorsten, Petersen, Cordula, Betz, Christian Stephan, Rothkamm, Kai, Nollau, Peter, Münscher, Adrian
Published in Scientific reports (19.09.2019)
Published in Scientific reports (19.09.2019)
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Journal Article
Marine alkaloid monanchoxymycalin C: a new specific activator of JNK1/2 kinase with anticancer properties
Dyshlovoy, Sergey A., Kaune, Moritz, Kriegs, Malte, Hauschild, Jessica, Busenbender, Tobias, Shubina, Larisa K., Makarieva, Tatyana N., Hoffer, Konstantin, Bokemeyer, Carsten, Graefen, Markus, Stonik, Valentin A., von Amsberg, Gunhild
Published in Scientific reports (06.08.2020)
Published in Scientific reports (06.08.2020)
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Journal Article
Synthesis and new DNA targeting activity of 6- and 7-tert-butylfascaplysins
Dyshlovoy, Sergey A., Mansour, Wael Y., Ramm, Natalia A., Hauschild, Jessica, Zhidkov, Maxim E., Kriegs, Malte, Zielinski, Alexandra, Hoffer, Konstantin, Busenbender, Tobias, Glumakova, Ksenia A., Spirin, Pavel V., Prassolov, Vladimir S., Tilki, Derya, Graefen, Markus, Bokemeyer, Carsten, von Amsberg, Gunhild
Published in Scientific reports (23.05.2024)
Published in Scientific reports (23.05.2024)
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Journal Article
Cytotoxic N-Methylpretrichodermamide B Reveals Anticancer Activity and Inhibits P-Glycoprotein in Drug-Resistant Prostate Cancer Cells
Dyshlovoy, Sergey A., Busenbender, Tobias, Hauschild, Jessica, Girich, Elena V., Kriegs, Malte, Hoffer, Konstantin, Graefen, Markus, Yurchenko, Anton N., Bokemeyer, Carsten, von Amsberg, Gunhild
Published in Marine drugs (23.09.2022)
Published in Marine drugs (23.09.2022)
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Journal Article
Ikaros sets the threshold for negative B-cell selection by regulation of the signaling strength of the AKT pathway
Ehm, Patrick A H, Horn, Stefan, Hoffer, Konstantin, Kriegs, Malte, Horn, Michael, Giehler, Susanne, Nalaskowski, Marcus, Rehbach, Christoph, Horstmann, Martin A, Jücker, Manfred
Published in Cell communication and signaling (12.07.2024)
Published in Cell communication and signaling (12.07.2024)
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Journal Article
G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells
Cetin, Meryem H, Rieckmann, Thorsten, Hoffer, Konstantin, Riepen, Britta, Christiansen, Sabrina, Gatzemeier, Fruzsina, Feyerabend, Simon, Schoof, Melanie, Schüller, Ulrich, Petersen, Cordula, Mynarek, Martin, Rothkamm, Kai, Kriegs, Malte, Struve, Nina
Published in Radiation oncology (London, England) (29.01.2023)
Published in Radiation oncology (London, England) (29.01.2023)
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Journal Article
Analysis of the Plasticity of Circulating Tumor Cells Reveals Differentially Regulated Kinases During the Suspension‐to‐Adherent Transition
Smit, Daniel J., Hoffer, Konstantin, Bettin, Bettina, Kriegs, Malte, Cayrefourcq, Laure, Schumacher, Udo, Pantel, Klaus, Alix‐Panabières, Catherine, Jücker, Manfred
Published in Cancer medicine (Malden, MA) (01.10.2024)
Published in Cancer medicine (Malden, MA) (01.10.2024)
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Journal Article
Efficacy and Mechanism of Action of Marine Alkaloid 3,10-Dibromofascaplysin in Drug-Resistant Prostate Cancer Cells
Dyshlovoy, Sergey A, Kaune, Moritz, Hauschild, Jessica, Kriegs, Malte, Hoffer, Konstantin, Busenbender, Tobias, Smirnova, Polina A, Zhidkov, Maxim E, Poverennaya, Ekaterina V, Oh-Hohenhorst, Su Jung, Spirin, Pavel V, Prassolov, Vladimir S, Tilki, Derya, Bokemeyer, Carsten, Graefen, Markus, von Amsberg, Gunhild
Published in Marine drugs (01.12.2020)
Published in Marine drugs (01.12.2020)
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Journal Article
2517: Kinomics identifies activated Src kinases as target for radiosensitization of head and neck cancer
Kriegs, Malte, Hoffer, Konstantin, Zech, Henrike Barbara, Bussmann, Lara, Bargen, Clara Marie von, Lange, Tobias, Koecher, Sabrina, Rieckmann, Thorsten, Betz, Christian, Petersen, Cordula, Rothkamm, Kai
Published in Radiotherapy and oncology (01.05.2024)
Published in Radiotherapy and oncology (01.05.2024)
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Journal Article
Src family kinase targeting in head and neck tumor cells using SU6656, PP2 and dasatinib
Vu, Anh Thu, Akingunsade, Lara, Hoffer, Konstantin, Petersen, Cordula, Betz, Christian Stephan, Rothkamm, Kai, Rieckmann, Thorsten, Bussmann, Lara, Kriegs, Malte
Published in Head & neck (01.01.2023)
Published in Head & neck (01.01.2023)
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Journal Article
Mean global DNA methylation serves as independent prognostic marker in IDH-wildtype glioblastoma
Eckhardt, Alicia, Drexler, Richard, Schoof, Melanie, Struve, Nina, Capper, David, Jelgersma, Claudius, Onken, Julia, Harter, Patrick N, Weber, Katharina J, Divé, Iris, Rothkamm, Kai, Hoffer, Konstantin, Klumpp, Lukas, Ganser, Katrin, Petersen, Cordula, Ricklefs, Franz, Kriegs, Malte, Schüller, Ulrich
Published in Neuro-oncology (Charlottesville, Va.) (04.03.2024)
Published in Neuro-oncology (Charlottesville, Va.) (04.03.2024)
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Journal Article
Analyzing tyrosine kinase activity in head and neck cancer by functional kinomics: Identification of hyperactivated Src family kinases as prognostic markers and potential targets
Bußmann, Lara, Hoffer, Konstantin, Bargen, Clara Marie, Droste, Conrad, Lange, Tobias, Kemmling, Julia, Schröder‐Schwarz, Jennifer, Vu, Anh Thu, Akingunsade, Lara, Nollau, Peter, Rangarajan, Savithri, Wijn, Rik, Oetting, Agnes, Müller, Christian, Böckelmann, Lukas Clemens, Zech, Henrike Barbara, Berger, Joanna Caroline, Möckelmann, Nikolaus, Busch, Chia‐Jung, Böttcher, Arne, Gatzemeier, Fruzsina, Klinghammer, Konrad, Simnica, Donjete, Binder, Mascha, Struve, Nina, Rieckmann, Thorsten, Schumacher, Udo, Clauditz, Till Sebastian, Betz, Christian Stephan, Petersen, Cordula, Rothkamm, Kai, Münscher, Adrian, Kriegs, Malte
Published in International journal of cancer (01.09.2021)
Published in International journal of cancer (01.09.2021)
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Journal Article
Kinomic comparison of snap frozen and ex vivo-cultured head and neck tumors
Berger, Joanna, Zech, Henrike Barbara, Hoffer, Konstantin, von Bargen, Clara Marie, Nordquist, Lena, Bussmann, Lara, Gatzemeier, Fruzsina, Busch, Chia-Jung, Möckelmann, Niko, Münscher, Adrian, Betz, Christian Stefan, Petersen, Cordula, Rothkamm, Kai, Rieckmann, Thorsten, Köcher, Sabrina, Kriegs, Malte
Published in Oral oncology (01.12.2021)
Published in Oral oncology (01.12.2021)
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Journal Article
Receptor tyrosine kinase MET as potential target of multi‐kinase inhibitor and radiosensitizer sorafenib in HNSCC
Beizaei, Kaweh, Gleißner, Lisa, Hoffer, Konstantin, Bußmann, Lara, Vu, Anh Thu, Steinmeister, Leonhard, Laban, Simon, Möckelmann, Nikolaus, Münscher, Adrian, Petersen, Cordula, Rothkamm, Kai, Kriegs, Malte
Published in Head & neck (01.01.2019)
Published in Head & neck (01.01.2019)
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Journal Article
Quantitative proteomics unveiled: Regulation of DNA double strand break repair by EGFR involves PARP1
Myllynen, Laura, Kwiatkowski, Marcel, Gleißner, Lisa, Riepen, Britta, Hoffer, Konstantin, Wurlitzer, Marcus, Petersen, Cordula, Dikomey, Ekkehard, Rothkamm, Kai, Schlüter, Hartmut, Kriegs, Malte
Published in Radiotherapy and oncology (01.09.2015)
Published in Radiotherapy and oncology (01.09.2015)
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Journal Article
Mass Spectrometric Comparison of HPV-Positive and HPV-Negative Oropharyngeal Cancer
Wurlitzer, Marcus, Möckelmann, Nikolaus, Kriegs, Malte, Vens, Maren, Omidi, Maryam, Hoffer, Konstantin, von Bargen, Clara, Möller-Koop, Christina, Witt, Melanie, Droste, Conrad, Oetting, Agnes, Petersen, Hannes, Busch, Chia-Jung, Münscher, Adrian, Schlüter, Hartmut, Clauditz, Till Sebastian, Rieckmann, Thorsten
Published in Cancers (11.06.2020)
Published in Cancers (11.06.2020)
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Journal Article
CBMT-16. EGFRvIII EXPRESSION CONFERS CHEMOSENSITIVITY BY INCREASING DNA MISMATCH REPAIR PROTEIN EXPRESSION AND REPLICATION STRESS
Struve, Nina, Binder, Zev A, Stead, Lucy F, Brend, Tim, Bagley, Stephen J, Faulkner, Claire, Ott, Leonie, Müller-Goebel, Justus, Weik, Anna-Sophie, Hoffer, Konstantin, Rieckmann, Thorsten, Christin Parplys, Ann, Burmester, Jasmin, Henze, Marvin, Morrissette, Jennifer J D, Schüller, Ulrich, Petersen, Cordula, Rothkamm, Kai, Kurian, Kathreena M, Short, Susan C, Kriegs, Malte
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2019)
Published in Neuro-oncology (Charlottesville, Va.) (11.11.2019)
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Journal Article
Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests
Kriegs, Malte, Kasten-Pisula, Ulla, Riepen, Britta, Hoffer, Konstantin, Struve, Nina, Myllynen, Laura, Braig, Friederike, Binder, Mascha, Rieckmann, Thorsten, Grénman, Reidar, Petersen, Cordula, Dikomey, Ekkehard, Rothkamm, Kai
Published in Oncotarget (19.07.2016)
Published in Oncotarget (19.07.2016)
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Journal Article
Effect of sorafenib on cisplatin-based chemoradiation in head and neck cancer cells
Möckelmann, Nikolaus, Rieckmann, Thorsten, Busch, Chia-Jung, Becker, Benjamin, Gleißner, Lisa, Hoffer, Konstantin, Omniczynski, Maria, Steinmeister, Leonhard, Laban, Simon, Grénman, Reidar, Petersen, Cordula, Rothkamm, Kai, Dikomey, Ekkehard, Knecht, Rainald, Kriegs, Malte
Published in Oncotarget (26.04.2016)
Published in Oncotarget (26.04.2016)
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Journal Article