Clinical Pharmacokinetics and Pharmacodynamics of Etravirine
Schöller-Gyüre, Monika, Kakuda, Thomas N., Raoof, Araz, De Smedt, Goedele, Hoetelmans, Richard M. W.
Published in Clinical pharmacokinetics (01.01.2009)
Published in Clinical pharmacokinetics (01.01.2009)
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Mechanistic Model Describing the Time Course of Humoral Immunity Following Ad26.COV2.S Vaccination in Non-Human Primates
Dari, Anna, Solforosi, Laura, Roozendaal, Ramon, Hoetelmans, Richard M W, Pérez-Ruixo, Juan-José, Boulton, Muriel
Published in The Journal of pharmacology and experimental therapeutics (01.10.2023)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2023)
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Pharmacokinetics of darunavir in fixed-dose combination with cobicistat compared with coadministration of darunavir and ritonavir as single agents in healthy volunteers
Kakuda, Thomas N, Opsomer, Magda, Timmers, Maarten, Iterbeke, Koen, Van De Casteele, Tom, Hillewaert, Vera, Petrovic, Romana, Hoetelmans, Richard M W
Published in Journal of clinical pharmacology (01.08.2014)
Published in Journal of clinical pharmacology (01.08.2014)
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Quantifying Antibody Persistence After a Single Dose of COVID‐19 Vaccine Ad26.COV2.S in Humans Using a Mechanistic Modeling and Simulation Approach
Dari, Anna, Boulton, Muriel, Neyens, Martine, Le Gars, Mathieu, Valenzuela, Belén, Shukarev, Georgi, Cárdenas, Vicky, Ruiz‐Guiñazú, Javier, Sadoff, Jerald, Hoetelmans, Richard M. W., Ruixo, Juan José Pérez
Published in Clinical pharmacology and therapeutics (01.02.2023)
Published in Clinical pharmacology and therapeutics (01.02.2023)
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Single‐ and multiple‐dose pharmacokinetics and safety of pimodivir, a novel, non‐nucleoside polymerase basic protein 2 subunit inhibitor of the influenza A virus polymerase complex, and interaction with oseltamivir: a Phase 1 open‐label study in healthy volunteers
Deleu, Sofie, Kakuda, Thomas N., Spittaels, Kurt, Vercauteren, Jurgen J., Hillewaert, Vera, Lwin, Amy, Leopold, Lorant, Hoetelmans, Richard M. W.
Published in British journal of clinical pharmacology (01.11.2018)
Published in British journal of clinical pharmacology (01.11.2018)
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The effect of different meal types on the pharmacokinetics of darunavir (TMC114)/ritonavir in HIV-negative healthy volunteers
Sekar, Vanitha, Kestens, Dries, Spinosa-Guzman, Sabrina, De Pauw, Martine, De Paepe, Els, Vangeneugden, Tony, Lefebvre, Eric, Hoetelmans, Richard M W
Published in Journal of clinical pharmacology (01.04.2007)
Published in Journal of clinical pharmacology (01.04.2007)
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The effect of single- and multiple-dose etravirine on a drug cocktail of representative cytochrome P450 probes and digoxin in healthy subjects
Kakuda, Thomas N, Van Solingen-Ristea, Rodica M, Onkelinx, Joelle, Stevens, Tanja, Aharchi, Fatima, De Smedt, Goedele, Peeters, Monika, Leopold, Lorant, Hoetelmans, Richard M W
Published in Journal of clinical pharmacology (01.04.2014)
Published in Journal of clinical pharmacology (01.04.2014)
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Minimal Pharmacokinetic Interaction between the Human Immunodeficiency Virus Nonnucleoside Reverse Transcriptase Inhibitor Etravirine and the Integrase Inhibitor Raltegravir in Healthy Subjects
ANDERSON, Matt S, KAKUDA, Thomas N, IWAMOTO, Marian, HANLEY, William, MILLER, Jutta, KOST, James T, STOLTZ, Randall, WENNING, Larissa A, STONE, Julie A, HOETELMANS, Richard M. W, WAGNER, John A
Published in Antimicrobial Agents and Chemotherapy (01.12.2008)
Published in Antimicrobial Agents and Chemotherapy (01.12.2008)
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Bioequivalence of a darunavir/cobicistat fixed-dose combination tablet versus single agents and food effect in healthy volunteers
Kakuda, Thomas N, Van De Casteele, Tom, Petrovic, Romana, Neujens, Mark, Salih, Hiba, Opsomer, Magda, Hoetelmans, Richard Mw
Published in Antiviral therapy (01.01.2014)
Published in Antiviral therapy (01.01.2014)
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Pharmacokinetic Interactions of Maraviroc with Darunavir-Ritonavir, Etravirine, and Etravirine-Darunavir-Ritonavir in Healthy Volunteers: Results of Two Drug Interaction Trials
KAKUDA, Thomas N, ABEL, Samantha, TWEEDY, Sarah, HOETELMANS, Richard M. W, DAVIS, John, HAMLIN, Julia, SCHÖLLER-GYÜRE, Monika, MACK, Rebecca, NDONGO, Noella, PETIT, Wendy, RIDGWAY, Caroline, SEKAR, Vanitha
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
Published in Antimicrobial Agents and Chemotherapy (01.05.2011)
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Pharmacokinetics of Multiple-Dose Darunavir in Combination with Low-Dose Ritonavir in Individuals with Mild-to-Moderate Hepatic Impairment
Sekar, Vanitha, Spinosa-Guzman, Sabrina, De Paepe, Els, Stevens, Tanja, Tomaka, Frank, De Pauw, Martine, Hoetelmans, Richard M. W.
Published in Clinical pharmacokinetics (01.05.2010)
Published in Clinical pharmacokinetics (01.05.2010)
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Journal Article
Pharmacokinetic interaction between etravirine or rilpivirine and telaprevir in healthy volunteers: A randomized, two-way crossover trial
Kakuda, Thomas N, Leopold, Lorant, Nijs, Steven, Vandevoorde, Ann, Crauwels, Herta M, Bertelsen, Kirk M, Stevens, Marita, Witek, James, van Delft, Yvon, Tomaka, Frank, Hoetelmans, Richard M W
Published in Journal of clinical pharmacology (01.05.2014)
Published in Journal of clinical pharmacology (01.05.2014)
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The effect of rilpivirine on the pharmacokinetics of methadone in HIV-negative volunteers
Crauwels, Herta M, van Heeswijk, Rolf P G, Vandevoorde, Ann, Buelens, Annemie, Stevens, Marita, Hoetelmans, Richard M W
Published in Journal of clinical pharmacology (01.02.2014)
Published in Journal of clinical pharmacology (01.02.2014)
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Pharmacokinetic evaluation of the interaction between etravirine and rifabutin or clarithromycin in HIV-negative, healthy volunteers: results from two Phase 1 studies
Kakuda, Thomas N, Woodfall, Brian, De Marez, Tine, Peeters, Monika, Vandermeulen, Kati, Aharchi, Fatima, Hoetelmans, Richard M W
Published in Journal of antimicrobial chemotherapy (01.03.2014)
Published in Journal of antimicrobial chemotherapy (01.03.2014)
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Pharmacokinetic interaction between TMC114/ritonavir and tenofovir disoproxil fumarate in healthy volunteers
Hoetelmans, Richard M. W., Mariën, Kris, De Pauw, Martine, Hill, Andrew, Peeters, Monika, Sekar, Vanitha, De Doncker, Piet, Woodfall, Brian, Lefebvre, Eric
Published in British journal of clinical pharmacology (01.11.2007)
Published in British journal of clinical pharmacology (01.11.2007)
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