Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE)
Samsom, Kris G, Bosch, Linda J W, Schipper, Luuk J, Roepman, Paul, de Bruijn, Ewart, Hoes, Louisa R, Riethorst, Immy, Schoenmaker, Lieke, van der Kolk, Lizet E, Retèl, Valesca P, Frederix, Geert W J, Buffart, Tineke E, van der Hoeven, Jacobus J M, Voest, Emile E, Cuppen, Edwin, Monkhorst, Kim, Meijer, Gerrit A
Published in BMC medical genomics (10.11.2020)
Published in BMC medical genomics (10.11.2020)
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Caring for patients with cancer in the COVID-19 era
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Published in Nature medicine (01.05.2020)
Published in Nature medicine (01.05.2020)
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Limited evolution of the actionable metastatic cancer genome under therapeutic pressure
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Published in Nature medicine (01.09.2021)
Published in Nature medicine (01.09.2021)
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Codon-specific KRAS mutations predict survival benefit of trifluridine/tipiracil in metastatic colorectal cancer
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Published in Nature medicine (01.03.2023)
Published in Nature medicine (01.03.2023)
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Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment
Hoes, Louisa R, van Berge Henegouwen, Jade M, van der Wijngaart, Hanneke, Zeverijn, Laurien J, van der Velden, Daphne L, van de Haar, Joris, Roepman, Paul, de Leng, Wendy J, Jansen, Anne M L, van Werkhoven, Erik, van der Noort, Vincent, Huitema, Alwin D R, Gort, Eelke H, de Groot, Jan Willem B, Kerver, Emile D, de Groot, Derk Jan, Erdkamp, Frans, Beerepoot, Laurens V, Hendriks, Mathijs P, Smit, Egbert F, van der Graaf, Winette T A, van Herpen, Carla M L, Labots, Mariette, Hoeben, Ann, Morreau, Hans, Lolkema, Martijn P, Cuppen, Edwin, Gelderblom, Hans, Verheul, Henk M W, Voest, Emile E
Published in Clinical cancer research (01.04.2022)
Published in Clinical cancer research (01.04.2022)
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Patients with Biallelic BRCA1/2 Inactivation Respond to Olaparib Treatment Across Histologic Tumor Types
van der Wijngaart, Hanneke, Hoes, Louisa R, van Berge Henegouwen, J Maxime, van der Velden, Daphne L, Zeverijn, Laurien J, Roepman, Paul, van Werkhoven, Erik, de Leng, Wendy W J, Jansen, Anne M L, Mehra, Niven, Robbrecht, Debbie G J, Labots, Mariette, de Groot, Derk Jan A, Hoeben, Ann, Hamberg, Paul, Gelderblom, Hans, Voest, Emile E, Verheul, Henk M W
Published in Clinical cancer research (15.11.2021)
Published in Clinical cancer research (15.11.2021)
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Maximizing Treatment Opportunities: Assessing Protocol Waivers' Impact on Safety and Outcome in the Drug Rediscovery Protocol
van Berge Henegouwen, Jade M, Zeverijn, Laurien J, Geurts, Birgit S, Hoes, Louisa R, van der Wijngaart, Hanneke, van der Noort, Vincent, Huitema, Alwin D R, de Vos, Filip Y F, Grünberg, Katrien, Bloemendal, Haiko J, Verheul, Henk M W, Voest, Emile E, Gelderblom, Hans
Published in Clinical cancer research (03.09.2024)
Published in Clinical cancer research (03.09.2024)
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Efficacy of pembrolizumab and biomarker analysis in patients with WGS-based intermediate to high tumor mutational load: results from the Drug Rediscovery Protocol
Geurts, Birgit S, Zeverijn, Laurien J, Leek, Lindsay V M, van Berge Henegouwen, Jade M, Hoes, Louisa R, van der Wijngaart, Hanneke, van der Noort, Vincent, van de Haar, Joris, van Ommen-Nijhof, Annemiek, Kok, Marleen, Roepman, Paul, Jansen, Anne M L, de Leng, Wendy W J, de Jonge, Maja J A, Hoeben, Ann, van Herpen, Carla M L, Westgeest, Hans M, Wessels, Lodewyk F A, Verheul, Henk M W, Gelderblom, Hans, Voest, Emile E
Published in Clinical cancer research (03.09.2024)
Published in Clinical cancer research (03.09.2024)
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Limited clinical activity of palbociclib and ribociclib monotherapy in advanced cancers with cyclin D‐CDK4/6 pathway alterations in the Dutch DRUP and Australian MoST trials
Zeverijn, Laurien J., Looze, Eleonora J., Thavaneswaran, Subotheni, Berge Henegouwen, J. Maxime, Simes, Robert J., Hoes, Louisa R., Sjoquist, Katrin M., Wijngaart, Hanneke, Sebastian, Lucille, Geurts, Birgit S., Lee, Chee K., Wit, Gijsbrecht F., Espinoza, David, Roepman, Paul, Lin, Frank P., Jansen, Anne M. L., Leng, Wendy W. J., Noort, Vincent, Leek, Lindsay V. M., Vos, Filip Y. F. L., Herpen, Carla M. L., Gelderblom, Hans, Verheul, Henk M. W., Thomas, David M., Voest, Emile E.
Published in International journal of cancer (01.10.2023)
Published in International journal of cancer (01.10.2023)
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The Innate Immune Landscape of dMMR/MSI Cancers Predicts the Outcome of Nivolumab Treatment: Results from the Drug Rediscovery Protocol
Zeverijn, Laurien J, Geurts, Birgit S, Battaglia, Thomas W, van Berge Henegouwen, Jade M, de Wit, Gijs F, Hoes, Louisa R, van der Wijngaart, Hanneke, van der Noort, Vincent, Roepman, Paul, de Leng, Wendy W J, Jansen, Anne M L, Chalabi, Myriam, van Herpen, Carla M L, Devriese, Lot A, Erdkamp, Frans L G, Labots, Mariette, de Jonge, Maja J A, Kerver, Emile D, Bins, Adriaan D, Leek, Lindsay V M, Notohardjo, Jessica C L, van den Eertwegh, Alfonsus J M, Wessels, Lodewyk F A, Verheul, Henk M W, Gelderblom, Hans, van de Haar, Joris, Voest, Emile E
Published in Clinical cancer research (01.10.2024)
Published in Clinical cancer research (01.10.2024)
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Characterization of discordance between mismatch repair deficiency and microsatellite instability testing may prevent inappropriate treatment with immunotherapy
Geurts, Birgit S, Zeverijn, Laurien J, Berge Henegouwen, Jade M, Wijngaart, Hanneke, Hoes, Louisa R, Wit, Gijs F, Spiekman, Ilse AC, Battaglia, Thomas W, Beek, Daphne M, Roepman, Paul, Jansen, Anne ML, Leng, Wendy WJ, Broeks, Annegien, Labots, Mariette, Herpen, Carla ML, Gelderblom, Hans, Verheul, Henk MW, Snaebjornsson, Petur, Voest, Emile E
Published in The Journal of pathology (01.07.2024)
Published in The Journal of pathology (01.07.2024)
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Efficacy, safety and biomarker analysis of durvalumab in patients with mismatch-repair deficient or microsatellite instability-high solid tumours
Geurts, Birgit S, Battaglia, Thomas W, van Berge Henegouwen, J Maxime, Zeverijn, Laurien J, de Wit, Gijs F, Hoes, Louisa R, van der Wijngaart, Hanneke, van der Noort, Vincent, Roepman, Paul, de Leng, Wendy W J, Jansen, Anne M L, Opdam, Frans L, de Jonge, Maja J A, Cirkel, Geert A, Labots, Mariette, Hoeben, Ann, Kerver, Emile D, Bins, Adriaan D, Erdkamp, Frans G L, van Rooijen, Johan M, Houtsma, Danny, Hendriks, Mathijs P, de Groot, Jan-Willem B, Verheul, Henk M W, Gelderblom, Hans, Voest, Emile E
Published in BMC cancer (04.03.2023)
Published in BMC cancer (04.03.2023)
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Author Correction: Caring for patients with cancer in the COVID-19 era
van de Haar, Joris, Hoes, Louisa R., Coles, Charlotte E., Seamon, Kenneth, Fröhling, Stefan, Jäger, Dirk, Valenza, Franco, de Braud, Filippo, De Petris, Luigi, Bergh, Jonas, Ernberg, Ingemar, Besse, Benjamin, Barlesi, Fabrice, Garralda, Elena, Piris-Giménez, Alejandro, Baumann, Michael, Apolone, Giovanni, Soria, Jean Charles, Tabernero, Josep, Caldas, Carlos, Voest, Emile E.
Published in Nature medicine (01.07.2020)
Published in Nature medicine (01.07.2020)
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