Cognitive correlates of α4β2 nicotinic acetylcholine receptors in mild Alzheimer's dementia
Sabri, Osama, Meyer, Philipp M, Gräf, Susanne, Hesse, Swen, Wilke, Stephan, Becker, Georg-Alexander, Rullmann, Michael, Patt, Marianne, Luthardt, Julia, Wagenknecht, Gudrun, Hoepping, Alexander, Smits, Rene, Franke, Annegret, Sattler, Bernhard, Tiepolt, Solveig, Fischer, Steffen, Deuther-Conrad, Winnie, Hegerl, Ulrich, Barthel, Henryk, Schönknecht, Peter, Brust, Peter
Published in Brain (London, England : 1878) (01.06.2018)
Published in Brain (London, England : 1878) (01.06.2018)
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Journal Article
Procedures for the GMP-Compliant Production and Quality Control of [ 18 F]PSMA-1007: A Next Generation Radiofluorinated Tracer for the Detection of Prostate Cancer
Cardinale, Jens, Martin, René, Remde, Yvonne, Schäfer, Martin, Hienzsch, Antje, Hübner, Sandra, Zerges, Anna-Maria, Marx, Heike, Hesse, Ronny, Weber, Klaus, Smits, Rene, Hoepping, Alexander, Müller, Marco, Neels, Oliver C, Kopka, Klaus
Published in Pharmaceuticals (Basel, Switzerland) (27.09.2017)
Published in Pharmaceuticals (Basel, Switzerland) (27.09.2017)
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Journal Article
First-in-human PET quantification study of cerebral α4β2 nicotinic acetylcholine receptors using the novel specific radioligand (−)-[18F]Flubatine
Sabri, Osama, Becker, Georg-Alexander, Meyer, Philipp M., Hesse, Swen, Wilke, Stephan, Graef, Susanne, Patt, Marianne, Luthardt, Julia, Wagenknecht, Gudrun, Hoepping, Alexander, Smits, René, Franke, Annegret, Sattler, Bernhard, Habermann, Bernd, Neuhaus, Petra, Fischer, Steffen, Tiepolt, Solveig, Deuther-Conrad, Winnie, Barthel, Henryk, Schönknecht, Peter, Brust, Peter
Published in NeuroImage (Orlando, Fla.) (01.09.2015)
Published in NeuroImage (Orlando, Fla.) (01.09.2015)
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Journal Article
(+)-[18F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand—results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzheimer’s disease and healthy controls
Tiepolt, Solveig, Becker, Georg-Alexander, Wilke, Stephan, Cecchin, Diego, Rullmann, Michael, Meyer, Philipp M., Barthel, Henryk, Hesse, Swen, Patt, Marianne, Luthardt, Julia, Wagenknecht, Gudrun, Sattler, Bernhard, Deuther-Conrad, Winnie, Ludwig, Friedrich-Alexander, Fischer, Steffen, Gertz, Hermann-Josef, Smits, René, Hoepping, Alexander, Steinbach, Jörg, Brust, Peter, Sabri, Osama
Published in European journal of nuclear medicine and molecular imaging (01.03.2021)
Published in European journal of nuclear medicine and molecular imaging (01.03.2021)
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Journal Article
Exploring the Metabolism of (+)-[ 18 F]Flubatine in Vitro and in Vivo: LC-MS/MS Aided Identification of Radiometabolites in a Clinical PET Study
Ludwig, Friedrich-Alexander, Fischer, Steffen, Smits, René, Deuther-Conrad, Winnie, Hoepping, Alexander, Tiepolt, Solveig, Patt, Marianne, Sabri, Osama, Brust, Peter
Published in Molecules (Basel, Switzerland) (20.02.2018)
Published in Molecules (Basel, Switzerland) (20.02.2018)
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Journal Article
LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[(18)F]Flubatine-A Positron Emission Tomography Radioligand for Imaging α4β2 Nicotinic Acetylcholine Receptors
Ludwig, Friedrich-Alexander, Smits, René, Fischer, Steffen, Donat, Cornelius K, Hoepping, Alexander, Brust, Peter, Steinbach, Jörg
Published in Molecules (Basel, Switzerland) (08.09.2016)
Published in Molecules (Basel, Switzerland) (08.09.2016)
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Journal Article
In vitro and in vivo Human Metabolism of (S)-[18F]Fluspidine – A Radioligand for Imaging σ1 Receptors With Positron Emission Tomography (PET)
Ludwig, Friedrich-Alexander, Fischer, Steffen, Houska, Richard, Hoepping, Alexander, Deuther-Conrad, Winnie, Schepmann, Dirk, Patt, Marianne, Meyer, Philipp M., Hesse, Swen, Becker, Georg-Alexander, Zientek, Franziska Ruth, Steinbach, Jörg, Wünsch, Bernhard, Sabri, Osama, Brust, Peter
Published in Frontiers in pharmacology (13.06.2019)
Published in Frontiers in pharmacology (13.06.2019)
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Journal Article
Image-Guided Development of Heterocyclic Sulfoxides as Ligands for Tau Neurofibrillary Tangles: From First-in-Man to Second-Generation Ligands
Rafique, Waqas, Kramer, Vasko, Pardo, Tania, Smits, René, Spilhaug, Mona M, Hoepping, Alexander, Savio, Eduardo, Engler, Henry, Kuljs, Rodrigo, Amaral, Horacio, Riss, Patrick J
Published in ACS omega (31.07.2018)
Published in ACS omega (31.07.2018)
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Journal Article
Radiation dosimetry of the α4β2 nicotinic receptor ligand (+)-[18F]flubatine, comparing preclinical PET/MRI and PET/CT to first-in-human PET/CT results
Kranz, Mathias, Sattler, Bernhard, Tiepolt, Solveig, Wilke, Stephan, Deuther-Conrad, Winnie, Donat, Cornelius K., Fischer, Steffen, Patt, Marianne, Schildan, Andreas, Patt, Jörg, Smits, René, Hoepping, Alexander, Steinbach, Jörg, Sabri, Osama, Brust, Peter
Published in EJNMMI physics (21.10.2016)
Published in EJNMMI physics (21.10.2016)
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Journal Article
Radiosynthesis and first preclinical evaluation of the novel norepinephrine transporter pet-ligand [11C]ME@HAPTHI
Rami-Mark, Christina, Berroterán-Infante, Neydher, Philippe, Cecile, Foltin, Stefanie, Vraka, Chrysoula, Hoepping, Alexander, Lanzenberger, Rupert, Hacker, Marcus, Mitterhauser, Markus, Wadsak, Wolfgang
Published in EJNMMI research (10.06.2015)
Published in EJNMMI research (10.06.2015)
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Journal Article
Phase III Study of 18F-PSMA-1007 Versus 18F-Fluorocholine PET/CT for Localization of Prostate Cancer Biochemical Recurrence: A Prospective, Randomized, Crossover Multicenter Study
Olivier, Pierre, Giraudet, Anne-Laure, Skanjeti, Andrea, Merlin, Charles, Weinmann, Pierre, Rudolph, Ines, Hoepping, Alexander, Gauthé, Mathieu
Published in The Journal of nuclear medicine (1978) (01.04.2023)
Published in The Journal of nuclear medicine (1978) (01.04.2023)
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Journal Article
Phase III Study of 18 F-PSMA-1007 Versus 18 F-Fluorocholine PET/CT for Localization of Prostate Cancer Biochemical Recurrence: A Prospective, Randomized, Crossover Multicenter Study
Olivier, Pierre, Giraudet, Anne-Laure, Skanjeti, Andrea, Merlin, Charles, Weinmann, Pierre, Rudolph, Ines, Hoepping, Alexander, Gauthé, Mathieu
Published in Journal of Nuclear Medicine (01.04.2023)
Published in Journal of Nuclear Medicine (01.04.2023)
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Journal Article
Enhanced copper-mediated (18)F-fluorination of aryl boronic esters provides eight radiotracers for PET applications
Preshlock, Sean, Calderwood, Samuel, Verhoog, Stefan, Tredwell, Matthew, Huiban, Mickael, Hienzsch, Antje, Gruber, Stefan, Wilson, Thomas C, Taylor, Nicholas J, Cailly, Thomas, Schedler, Michael, Collier, Thomas Lee, Passchier, Jan, Smits, René, Mollitor, Jan, Hoepping, Alexander, Mueller, Marco, Genicot, Christophe, Mercier, Joël, Gouverneur, Véronique
Published in Chemical communications (Cambridge, England) (28.06.2016)
Published in Chemical communications (Cambridge, England) (28.06.2016)
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Journal Article
Combination of [18F]FDG and [18F]PSMA-1007 PET/CT predicts tumour aggressiveness at staging and biochemical failure postoperatively in patients with prostate cancer
Kim, Jisu, Lee, Seunghwan, Kim, Dongwoo, Kim, Hyun Jeong, Oh, Kyeong Taek, Kim, Sun Jung, Choi, Young Deuk, Giesel, Frederik L., Kopka, Klaus, Hoepping, Alexander, Lee, Misu, Yun, Mijin
Published in European journal of nuclear medicine and molecular imaging (01.05.2024)
Published in European journal of nuclear medicine and molecular imaging (01.05.2024)
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Journal Article
Multiparametric MRI and 18 F-PSMA-1007 PET/CT for the Detection of Clinically Significant Prostate Cancer
Privé, Bastiaan M, Israël, Bas, Janssen, Marcel J R, van der Leest, Marloes M G, de Rooij, Maarten, van Ipenburg, Jolique A, Jonker, Marianne, Peters, Steffie M B, de Groot, Michel, Zámecnik, Patrik, Hoepping, Alexander, Bomers, Joyce G, Gotthardt, Martin, Sedelaar, J P Michiel, Barentsz, Jelle O, van Oort, Inge M, Nagarajah, James
Published in Radiology (01.05.2024)
Published in Radiology (01.05.2024)
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Journal Article
Synthesis of novel PSMA ligands and preclinical evaluation of [99mTc]TcO-ABX474, a radioligand for SPECT imaging of prostate cancer
Ludwig, Friedrich-Alexander, Lis, Christian, Ullrich, Martin, Lankau, Hans-Joachim, Sihver, Wiebke, Joseph, Desna, Eiselt, Erik, Meyer, Christoph, Guendel, Daniel, Deuther-Conrad, Winnie, Brust, Peter, Donat, Cornelius, Bachmann, Michael, Pietzsch, Hans-Jurgen, Pietzsch, Jens, Fischer, Steffen, Kopka, Klaus, Hoepping, Alexander
Published in Nuclear medicine and biology (01.11.2022)
Published in Nuclear medicine and biology (01.11.2022)
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Journal Article
O-29 - Synthesis of novel PSMA ligands and preclinical evaluation of [99mTc]TcO-ABX474, a radioligand for SPECT imaging of prostate cancer
Ludwig, Friedrich-Alexander, Lis, Christian, Ullrich, Martin, Lankau, Hans-Joachim, Sihver, Wiebke, Joseph, Desna, Eiselt, Erik, Meyer, Christoph, Guendel, Daniel, Deuther-Conrad, Winnie, Brust, Peter, Donat, Cornelius, Bachmann, Michael, Pietzsch, Hans-Jurgen, Pietzsch, Jens, Fischer, Steffen, Kopka, Klaus, Hoepping, Alexander
Published in Nuclear medicine and biology (01.11.2022)
Published in Nuclear medicine and biology (01.11.2022)
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Journal Article
Preclinical Evaluation of a Companion Diagnostic Radiopharmaceutical, [18F]PSMA-1007, in a Subcutaneous Prostate Cancer Xenograft Mouse Model
Kim, Su Bin, Song, In Ho, Kim, Seon Yoo, Ko, Hae Young, Kil, Hee Seup, Chi, Dae Yoon, Giesel, Frederik L., Kopka, Klaus, Hoepping, Alexander, Chun, Joong-Hyun, Park, Hyun Soo, Yun, Mijin, Kim, Sang Eun
Published in Molecular pharmaceutics (06.02.2023)
Published in Molecular pharmaceutics (06.02.2023)
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Journal Article
GMP-compliant fully automated single-step radiosynthesis of [^sup 18^F]PSMA-1007 using SPE cartridge purification
Neels, Oliver, Martin, Rene, Cardinale, Jens, Smits, Rene, Schaefer, Martin, Hoepping, Alexander, Giesel, Frederik, Mueller, Marco, Kopka, Klaus
Published in The Journal of nuclear medicine (1978) (01.05.2018)
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Published in The Journal of nuclear medicine (1978) (01.05.2018)
Journal Article
요오드티로신 유도체 및 요오드티로신 유도체를 제조하기위한 방법
JOSEPH DESNA, KOSTER STEFAN DAVID, EISELT ERIK, MEYER CHRISTOPH, HOEPPING ALEXANDER
Year of Publication 04.09.2023
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Year of Publication 04.09.2023
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