Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing
Gombar, Saurabh, Jung, Hwa Jin, Dong, Feng, Calder, Brent, Atzmon, Gil, Barzilai, Nir, Tian, Xiao-Li, Pothof, Joris, Hoeijmakers, Jan H J, Campisi, Judith, Vijg, Jan, Suh, Yousin
Published in BMC genomics (31.07.2012)
Published in BMC genomics (31.07.2012)
Get full text
Journal Article
DNA damage‐induced replication stress results in PA200‐proteasome‐mediated degradation of acetylated histones
Mandemaker, Imke K, Geijer, Marit E, Kik, Iris, Bezstarosti, Karel, Rijkers, Erikjan, Raams, Anja, Janssens, Roel C, Lans, Hannes, Hoeijmakers, Jan HJ, Demmers, Jeroen AA, Vermeulen, Wim, Marteijn, Jurgen A
Published in EMBO reports (01.10.2018)
Published in EMBO reports (01.10.2018)
Get full text
Journal Article
Trichothiodystrophy‐associated MPLKIP maintains DBR1 levels for proper lariat debranching and ectodermal differentiation
Theil, Arjan F, Pines, Alex, Kalayci, Tuğba, Heredia‐Genestar, José M, Raams, Anja, Rietveld, Marion H, Sridharan, Sriram, Tanis, Sabine EJ, Mulder, Klaas W, Büyükbabani, Nesimi, Karaman, Birsen, Uyguner, Zehra O, Kayserili, Hülya, Hoeijmakers, Jan HJ, Lans, Hannes, Demmers, Jeroen AA, Pothof, Joris, Altunoglu, Umut, El Ghalbzouri, Abdoelwaheb, Vermeulen, Wim
Published in EMBO molecular medicine (08.11.2023)
Published in EMBO molecular medicine (08.11.2023)
Get full text
Journal Article
Understanding nucleotide excision repair and its roles in cancer and ageing
Marteijn, Jurgen A., Lans, Hannes, Vermeulen, Wim, Hoeijmakers, Jan H. J.
Published in Nature reviews. Molecular cell biology (01.07.2014)
Published in Nature reviews. Molecular cell biology (01.07.2014)
Get full text
Journal Article
Nuclear Genomic Instability and Aging
Niedernhofer, Laura J, Gurkar, Aditi U, Wang, Yinsheng, Vijg, Jan, Hoeijmakers, Jan H.J, Robbins, Paul D
Published in Annual review of biochemistry (20.06.2018)
Published in Annual review of biochemistry (20.06.2018)
Get full text
Journal Article
Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options
Vermeij, Wilbert P, Hoeijmakers, Jan H.J, Pothof, Joris
Published in Annual review of pharmacology and toxicology (01.01.2016)
Published in Annual review of pharmacology and toxicology (01.01.2016)
Get full text
Journal Article
DNA damage and ageing: new-age ideas for an age-old problem
H.J. Hoeijmakers, Jan, Vijg, Jan, van der Horst, Gijsbertus T.J, Garinis, George A
Published in Nature cell biology (01.11.2008)
Published in Nature cell biology (01.11.2008)
Get full text
Journal Article
Nucleotide excision repair-initiating proteins bind to oxidative DNA lesions in vivo
Menoni, Hervé, Hoeijmakers, Jan H J, Vermeulen, Wim
Published in The Journal of cell biology (24.12.2012)
Published in The Journal of cell biology (24.12.2012)
Get full text
Journal Article
Aging: not all DNA damage is equal
Vermeij, Wilbert P, Hoeijmakers, Jan HJ, Pothof, Joris
Published in Current opinion in genetics & development (01.06.2014)
Published in Current opinion in genetics & development (01.06.2014)
Get full text
Journal Article
Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment
Naipal, Kishan A T, Verkaik, Nicole S, Ameziane, Najim, van Deurzen, Carolien H M, Ter Brugge, Petra, Meijers, Matty, Sieuwerts, Anieta M, Martens, John W, O'Connor, Mark J, Vrieling, Harry, Hoeijmakers, Jan H J, Jonkers, Jos, Kanaar, Roland, de Winter, Johan P, Vreeswijk, Maaike P, Jager, Agnes, van Gent, Dik C
Published in Clinical cancer research (15.09.2014)
Published in Clinical cancer research (15.09.2014)
Get full text
Journal Article
Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks
Motegi, Akira, Liaw, Hung-Jiun, Lee, Kyoo-Young, Roest, Henk P, Maas, Alex, Wu, Xiaoli, Moinova, Helen, Markowitz, Sanford D, Ding, Hao, Hoeijmakers, Jan H.J, Myung, Kyungjae
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2008)
Get full text
Journal Article
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
Robinson, Andria Rasile, Appeldoorn, Esther, Hoeijmakers, Jan H. J, Theil, Arjan F, Raams, Anja, Odijk, Hanny, Kleijer, Wim J, Meinecke, Peter, van Leeuwen, Wibeke, Lalai, Astrid S, Ahmad, Anwaar, Niedernhofer, Laura J, Vijg, Jan, Jaspers, Nicolaas G. J, Garinis, George A, Vermeulen, Wim, van der Horst, Gijsbertus T. J, Oostendorp, Roos
Published in Nature (21.12.2006)
Published in Nature (21.12.2006)
Get full text
Journal Article
Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease
Sepe, Sara, Milanese, Chiara, Gabriels, Sylvia, Derks, Kasper W.J., Payan-Gomez, Cesar, van IJcken, Wilfred F.J., Rijksen, Yvonne M.A., Nigg, Alex L., Moreno, Sandra, Cerri, Silvia, Blandini, Fabio, Hoeijmakers, Jan H.J., Mastroberardino, Pier G.
Published in Cell reports (Cambridge) (31.05.2016)
Published in Cell reports (Cambridge) (31.05.2016)
Get full text
Journal Article
Priming of microglia in a DNA-repair deficient model of accelerated aging
Raj, Divya D.A, Jaarsma, Dick, Holtman, Inge R, Olah, Marta, Ferreira, Filipa M, Schaafsma, Wandert, Brouwer, Nieske, Meijer, Michel M, de Waard, Monique C, van der Pluijm, Ingrid, Brandt, Renata, Kreft, Karim L, Laman, Jon D, de Haan, Gerald, Biber, Knut P.H, Hoeijmakers, Jan H.J, Eggen, Bart J.L, Boddeke, Hendrikus W.G.M
Published in Neurobiology of aging (01.09.2014)
Published in Neurobiology of aging (01.09.2014)
Get full text
Journal Article
Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability
Trego, Kelly S., Groesser, Torsten, Davalos, Albert R., Parplys, Ann C., Zhao, Weixing, Nelson, Michael R., Hlaing, Ayesu, Shih, Brian, Rydberg, Björn, Pluth, Janice M., Tsai, Miaw-Sheue, Hoeijmakers, Jan H.J., Sung, Patrick, Wiese, Claudia, Campisi, Judith, Cooper, Priscilla K.
Published in Molecular cell (18.02.2016)
Published in Molecular cell (18.02.2016)
Get full text
Journal Article
Recognition of DNA damage by XPC coincides with disruption of the XPC-RAD23 complex
Bergink, Steven, Toussaint, Wendy, Luijsterburg, Martijn S, Dinant, Christoffel, Alekseev, Sergey, Hoeijmakers, Jan H J, Dantuma, Nico P, Houtsmuller, Adriaan B, Vermeulen, Wim
Published in The Journal of cell biology (19.03.2012)
Published in The Journal of cell biology (19.03.2012)
Get full text
Journal Article