The central role of DNA damage in the ageing process
Schumacher, Björn, Pothof, Joris, Vijg, Jan, Hoeijmakers, Jan H. J.
Published in Nature (London) (29.04.2021)
Published in Nature (London) (29.04.2021)
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Journal Article
The DNA damage response to transcription stress
Lans, Hannes, Hoeijmakers, Jan H. J., Vermeulen, Wim, Marteijn, Jurgen A.
Published in Nature reviews. Molecular cell biology (01.12.2019)
Published in Nature reviews. Molecular cell biology (01.12.2019)
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Journal Article
Cellular senescence drives age-dependent hepatic steatosis
Ogrodnik, Mikolaj, Miwa, Satomi, Tchkonia, Tamar, Tiniakos, Dina, Wilson, Caroline L., Lahat, Albert, Day, Christoper P., Burt, Alastair, Palmer, Allyson, Anstee, Quentin M., Grellscheid, Sushma Nagaraja, Hoeijmakers, Jan H J., Barnhoorn, Sander, Mann, Derek A., Bird, Thomas G., Vermeij, Wilbert P., Kirkland, James L., Passos, João F., von Zglinicki, Thomas, Jurk, Diana
Published in Nature communications (13.06.2017)
Published in Nature communications (13.06.2017)
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Journal Article
Understanding nucleotide excision repair and its roles in cancer and ageing
Marteijn, Jurgen A., Lans, Hannes, Vermeulen, Wim, Hoeijmakers, Jan H. J.
Published in Nature reviews. Molecular cell biology (01.07.2014)
Published in Nature reviews. Molecular cell biology (01.07.2014)
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Journal Article
Nuclear Genomic Instability and Aging
Niedernhofer, Laura J, Gurkar, Aditi U, Wang, Yinsheng, Vijg, Jan, Hoeijmakers, Jan H.J, Robbins, Paul D
Published in Annual review of biochemistry (20.06.2018)
Published in Annual review of biochemistry (20.06.2018)
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Journal Article
Age to survive: DNA damage and aging
Schumacher, Björn, Garinis, George A, Hoeijmakers, Jan H.J
Published in Trends in genetics (01.02.2008)
Published in Trends in genetics (01.02.2008)
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Journal Article
Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin
Kim, Dong Eun, Dollé, Martijn E. T., Vermeij, Wilbert P., Gyenis, Akos, Vogel, Katharina, Hoeijmakers, Jan H. J., Wiley, Christopher D., Davalos, Albert R., Hasty, Paul, Desprez, Pierre‐Yves, Campisi, Judith
Published in Aging cell (01.03.2020)
Published in Aging cell (01.03.2020)
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Journal Article
Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options
Vermeij, Wilbert P, Hoeijmakers, Jan H.J, Pothof, Joris
Published in Annual review of pharmacology and toxicology (01.01.2016)
Published in Annual review of pharmacology and toxicology (01.01.2016)
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Journal Article
UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair
Schwertman, Petra, Lagarou, Anna, Dekkers, Dick H W, Raams, Anja, van der Hoek, Adriana C, Laffeber, Charlie, Hoeijmakers, Jan H J, Demmers, Jeroen A A, Fousteri, Maria, Vermeulen, Wim, Marteijn, Jurgen A
Published in Nature genetics (01.05.2012)
Published in Nature genetics (01.05.2012)
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Journal Article
The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics
Llerena Schiffmacher, Diana A., Lee, Shun-Hsiao, Kliza, Katarzyna W., Theil, Arjan F., Akita, Masaki, Helfricht, Angela, Bezstarosti, Karel, Gonzalo-Hansen, Camila, van Attikum, Haico, Verlaan-de Vries, Matty, Vertegaal, Alfred C. O., Hoeijmakers, Jan H. J., Marteijn, Jurgen A., Lans, Hannes, Demmers, Jeroen A. A., Vermeulen, Michiel, Sixma, Titia K., Ogi, Tomoo, Vermeulen, Wim, Pines, Alex
Published in Nature communications (29.07.2024)
Published in Nature communications (29.07.2024)
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Journal Article
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
Robinson, Andria Rasile, Appeldoorn, Esther, Hoeijmakers, Jan H. J, Theil, Arjan F, Raams, Anja, Odijk, Hanny, Kleijer, Wim J, Meinecke, Peter, van Leeuwen, Wibeke, Lalai, Astrid S, Ahmad, Anwaar, Niedernhofer, Laura J, Vijg, Jan, Jaspers, Nicolaas G. J, Garinis, George A, Vermeulen, Wim, van der Horst, Gijsbertus T. J, Oostendorp, Roos
Published in Nature (21.12.2006)
Published in Nature (21.12.2006)
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Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks
Motegi, Akira, Liaw, Hung-Jiun, Lee, Kyoo-Young, Roest, Henk P, Maas, Alex, Wu, Xiaoli, Moinova, Helen, Markowitz, Sanford D, Ding, Hao, Hoeijmakers, Jan H.J, Myung, Kyungjae
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2008)
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Journal Article
Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development
Lans, Hannes, Marteijn, Jurgen A, Schumacher, Björn, Hoeijmakers, Jan H J, Jansen, Gert, Vermeulen, Wim
Published in PLoS genetics (06.05.2010)
Published in PLoS genetics (06.05.2010)
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Journal Article
Chromosomal stability and the DNA double-stranded break connection
van Gent, Dik C, Hoeijmakers, Jan H. J, Kanaar, Roland
Published in Nature reviews. Genetics (01.03.2001)
Published in Nature reviews. Genetics (01.03.2001)
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Journal Article
Rbm3 deficiency leads to transcriptome-wide splicing alterations
Erkelenz, Steffen, Grzonka, Marta, Papadakis, Antonios, Schaal, Heiner, Hoeijmakers, Jan H J, Gyenis, Ákos
Published in RNA biology (31.12.2024)
Published in RNA biology (31.12.2024)
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Journal Article
Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing
Gombar, Saurabh, Jung, Hwa Jin, Dong, Feng, Calder, Brent, Atzmon, Gil, Barzilai, Nir, Tian, Xiao-Li, Pothof, Joris, Hoeijmakers, Jan H J, Campisi, Judith, Vijg, Jan, Suh, Yousin
Published in BMC genomics (31.07.2012)
Published in BMC genomics (31.07.2012)
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Journal Article
Nucleotide excision repair-initiating proteins bind to oxidative DNA lesions in vivo
Menoni, Hervé, Hoeijmakers, Jan H J, Vermeulen, Wim
Published in The Journal of cell biology (24.12.2012)
Published in The Journal of cell biology (24.12.2012)
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Journal Article
Aging: not all DNA damage is equal
Vermeij, Wilbert P, Hoeijmakers, Jan HJ, Pothof, Joris
Published in Current opinion in genetics & development (01.06.2014)
Published in Current opinion in genetics & development (01.06.2014)
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