Restricted diet delays accelerated ageing and genomic stress in DNA-repair-deficient mice
Vermeij, W. P., Dollé, M. E. T., Reiling, E., Jaarsma, D., Payan-Gomez, C., Bombardieri, C. R., Wu, H., Roks, A. J. M., Botter, S. M., van der Eerden, B. C., Youssef, S. A., Kuiper, R. V., Nagarajah, B., van Oostrom, C. T., Brandt, R. M. C., Barnhoorn, S., Imholz, S., Pennings, J. L. A., de Bruin, A., Gyenis, Á., Pothof, J., Vijg, J., van Steeg, H., Hoeijmakers, J. H. J.
Published in Nature (London) (15.09.2016)
Published in Nature (London) (15.09.2016)
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Cellular senescence drives age-dependent hepatic steatosis
Ogrodnik, Mikolaj, Miwa, Satomi, Tchkonia, Tamar, Tiniakos, Dina, Wilson, Caroline L., Lahat, Albert, Day, Christoper P., Burt, Alastair, Palmer, Allyson, Anstee, Quentin M., Grellscheid, Sushma Nagaraja, Hoeijmakers, Jan H J., Barnhoorn, Sander, Mann, Derek A., Bird, Thomas G., Vermeij, Wilbert P., Kirkland, James L., Passos, João F., von Zglinicki, Thomas, Jurk, Diana
Published in Nature communications (13.06.2017)
Published in Nature communications (13.06.2017)
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Mass-loss rate and local thermodynamic state of the KELT-9 b thermosphere from the hydrogen Balmer series
Wyttenbach, A., Mollière, P., Ehrenreich, D., Cegla, H. M., Bourrier, V., Lovis, C., Pino, L., Allart, R., Seidel, J. V., Hoeijmakers, H. J., Nielsen, L. D., Lavie, B., Pepe, F., Bonfils, X., Snellen, I. A. G.
Published in Astronomy and astrophysics (Berlin) (01.06.2020)
Published in Astronomy and astrophysics (Berlin) (01.06.2020)
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A search for TiO in the optical high-resolution transmission spectrum of HD 209458b: Hindrance due to inaccuracies in the line database
Hoeijmakers, H. J., de Kok, R. J., Snellen, I. A. G., Brogi, M., Birkby, J. L., Schwarz, H.
Published in Astronomy and astrophysics (Berlin) (01.03.2015)
Published in Astronomy and astrophysics (Berlin) (01.03.2015)
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Optical phase curve of the ultra-hot Jupiter WASP-121b
Bourrier, V., Kitzmann, D., Kuntzer, T., Nascimbeni, V., Lendl, M., Lavie, B., Hoeijmakers, H. J., Pino, L., Ehrenreich, D., Heng, K., Allart, R., Cegla, H. M., Dumusque, X., Melo, C., Astudillo-Defru, N., Caldwell, D. A., Cretignier, M., Giles, H., Henze, C. E., Jenkins, J., Lovis, C., Murgas, F., Pepe, F., Ricker, G. R., Rose, M. E., Seager, S., Segransan, D., Suárez-Mascareño, A., Udry, S., Vanderspek, R., Wyttenbach, A.
Published in Astronomy and astrophysics (Berlin) (01.05.2020)
Published in Astronomy and astrophysics (Berlin) (01.05.2020)
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Search for an exosphere in sodium and calcium in the transmission spectrum of exoplanet 55 Cancri e
Ridden-Harper, A. R., Snellen, I. A. G., Keller, C. U., de Kok, R. J., Di Gloria, E., Hoeijmakers, H. J., Brogi, M., Fridlund, M., Vermeersen, B. L. A., van Westrenen, W.
Published in Astronomy and astrophysics (Berlin) (01.09.2016)
Published in Astronomy and astrophysics (Berlin) (01.09.2016)
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Journal Article
The central role of DNA damage in the ageing process
Schumacher, Björn, Pothof, Joris, Vijg, Jan, Hoeijmakers, Jan H. J.
Published in Nature (London) (29.04.2021)
Published in Nature (London) (29.04.2021)
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The small CRL4CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics
Llerena Schiffmacher, Diana A., Lee, Shun-Hsiao, Kliza, Katarzyna W., Theil, Arjan F., Akita, Masaki, Helfricht, Angela, Bezstarosti, Karel, Gonzalo-Hansen, Camila, van Attikum, Haico, Verlaan-de Vries, Matty, Vertegaal, Alfred C. O., Hoeijmakers, Jan H. J., Marteijn, Jurgen A., Lans, Hannes, Demmers, Jeroen A. A., Vermeulen, Michiel, Sixma, Titia K., Ogi, Tomoo, Vermeulen, Wim, Pines, Alex
Published in Nature communications (29.07.2024)
Published in Nature communications (29.07.2024)
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Chromosomal stability and the DNA double-stranded break connection
van Gent, Dik C, Hoeijmakers, Jan H. J, Kanaar, Roland
Published in Nature reviews. Genetics (01.03.2001)
Published in Nature reviews. Genetics (01.03.2001)
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Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks
Motegi, Akira, Liaw, Hung-Jiun, Lee, Kyoo-Young, Roest, Henk P, Maas, Alex, Wu, Xiaoli, Moinova, Helen, Markowitz, Sanford D, Ding, Hao, Hoeijmakers, Jan H.J, Myung, Kyungjae
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (26.08.2008)
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The DNA damage response to transcription stress
Lans, Hannes, Hoeijmakers, Jan H. J., Vermeulen, Wim, Marteijn, Jurgen A.
Published in Nature reviews. Molecular cell biology (01.12.2019)
Published in Nature reviews. Molecular cell biology (01.12.2019)
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Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development
Lans, Hannes, Marteijn, Jurgen A, Schumacher, Björn, Hoeijmakers, Jan H J, Jansen, Gert, Vermeulen, Wim
Published in PLoS genetics (06.05.2010)
Published in PLoS genetics (06.05.2010)
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A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis
Robinson, Andria Rasile, Appeldoorn, Esther, Hoeijmakers, Jan H. J, Theil, Arjan F, Raams, Anja, Odijk, Hanny, Kleijer, Wim J, Meinecke, Peter, van Leeuwen, Wibeke, Lalai, Astrid S, Ahmad, Anwaar, Niedernhofer, Laura J, Vijg, Jan, Jaspers, Nicolaas G. J, Garinis, George A, Vermeulen, Wim, van der Horst, Gijsbertus T. J, Oostendorp, Roos
Published in Nature (21.12.2006)
Published in Nature (21.12.2006)
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In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration
van't Sant, Lisanne J, White, Joshua J, Hoeijmakers, Jan H. J, Vermeij, Wilbert P, Jaarsma, Dick
Published in Acta neuropathologica communications (21.05.2021)
Published in Acta neuropathologica communications (21.05.2021)
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DNA damage in normally and prematurely aged mice
Maslov, Alexander Y., Ganapathi, Shireen, Westerhof, Maaike, Quispe‐Tintaya, Wilber, White, Ryan R., Van Houten, Bennett, Reiling, Erwin, Dollé, Martijn E. T., Steeg, Harry, Hasty, Paul, Hoeijmakers, Jan H. J., Vijg, Jan
Published in Aging cell (01.06.2013)
Published in Aging cell (01.06.2013)
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Silencing of Unpaired Chromatin and Histone H2A Ubiquitination in Mammalian Meiosis
Baarends, Willy M., Wassenaar, Evelyne, van der Laan, Roald, Hoogerbrugge, Jos, Sleddens-Linkels, Esther, Hoeijmakers, Jan H. J., de Boer, Peter, Grootegoed, J. Anton
Published in Molecular and Cellular Biology (01.02.2005)
Published in Molecular and Cellular Biology (01.02.2005)
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Delayed and accelerated aging share common longevity assurance mechanisms
Schumacher, Björn, van der Pluijm, Ingrid, Moorhouse, Michael J, Kosteas, Theodore, Robinson, Andria Rasile, Suh, Yousin, Breit, Timo M, van Steeg, Harry, Niedernhofer, Laura J, van Ijcken, Wilfred, Bartke, Andrzej, Spindler, Stephen R, Hoeijmakers, Jan H J, van der Horst, Gijsbertus T J, Garinis, George A
Published in PLoS genetics (01.08.2008)
Published in PLoS genetics (01.08.2008)
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Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology
Jaarsma, Dick, van der Pluijm, Ingrid, de Waard, Monique C, Haasdijk, Elize D, Brandt, Renata, Vermeij, Marcel, Rijksen, Yvonne, Maas, Alex, van Steeg, Harry, Hoeijmakers, Jan H J, van der Horst, Gijsbertus T J
Published in PLoS genetics (01.12.2011)
Published in PLoS genetics (01.12.2011)
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