Search Results - "Hocková, Dana" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer

MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer

by Meena, Jitendra K., Wang, Jarey H., Neill, Nicholas J., Keough, Dianne, Putluri, Nagireddy, Katsonis, Panagiotis, Koire, Amanda M., Lee, Hyemin, Bowling, Elizabeth A., Tyagi, Siddhartha, Orellana, Mayra, Dominguez-Vidaña, Rocio, Li, Heyuan, Eagle, Kenneth, Danan, Charles, Chung, Hsiang-Ching, Yang, Andrew D., Wu, William, Kurley, Sarah J., Ho, Brian M., Zoeller, Joseph R., Olson, Calla M., Meerbrey, Kristen L., Lichtarge, Olivier, Sreekumar, Arun, Dacso, Clifford C., Guddat, Luke W., Rejman, Dominik, Hocková, Dana, Janeba, Zlatko, Simon, Lukas M., Lin, Charles Y., Pillon, Monica C., Westbrook, Thomas F.
Published in Cancer discovery (04.09.2024)

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5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidinesAcyclic Nucleoside Phosphonate Analogues with Antiviral Activity

5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidinesAcyclic Nucleoside Phosphonate Analogues with Antiviral Activity

by Hocková, Dana, Holý, Antonín, Masojídková, Milena, Andrei, Graciela, Snoeck, Robert, De Clercq, Erik, Balzarini, Jan
Published in Journal of medicinal chemistry (06.11.2003)

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Acyclic nucleoside phosphonates with adenine nucleobase inhibit Trypanosoma brucei adenine phosphoribosyltransferase in vitro

Acyclic nucleoside phosphonates with adenine nucleobase inhibit Trypanosoma brucei adenine phosphoribosyltransferase in vitro

by Doleželová, Eva, Klejch, Tomáš, Špaček, Petr, Slapničková, Martina, Guddat, Luke, Hocková, Dana, Zíková, Alena
Published in Scientific reports (25.06.2021)

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Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2-(phosphonomethoxy)ethoxy]pyrimidine and related compounds

Synthesis and antiviral activity of 2,4-diamino-5-cyano-6-[2-(phosphonomethoxy)ethoxy]pyrimidine and related compounds

by Hocková, Dana, Holý, Antonı́n, Masojı́dková, Milena, Andrei, Graciela, Snoeck, Robert, De Clercq, Erik, Balzarini, Jan
Published in Bioorganic & medicinal chemistry (15.06.2004)

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Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6‑Oxopurine Phosphoribosyltransferases

Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6‑Oxopurine Phosphoribosyltransferases

by Klejch, Tomáš, Keough, Dianne T, King, Gordon, Doleželová, Eva, Česnek, Michal, Buděšínský, Miloš, Zíková, Alena, Janeba, Zlatko, Guddat, Luke W, Hocková, Dana
Published in Journal of medicinal chemistry (10.03.2022)

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Hypoxanthine-Guanine Phosphoribosyltransferase Is Dispensable for Mycobacterium smegmatis Viability

Hypoxanthine-Guanine Phosphoribosyltransferase Is Dispensable for Mycobacterium smegmatis Viability

by Knejzlík, Zdeněk, Herkommerová, Klára, Hocková, Dana, Pichová, Iva
Published in Journal of bacteriology (11.02.2020)

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Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group As Inhibitors of the Human, Plasmodium falciparum and vivax 6‑Oxopurine Phosphoribosyltransferases and Their Prodrugs As Antimalarial Agents

Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group As Inhibitors of the Human, Plasmodium falciparum and vivax 6‑Oxopurine Phosphoribosyltransferases and Their Prodrugs As Antimalarial Agents

by Keough, Dianne T, Hocková, Dana, Janeba, Zlatko, Wang, Tzu-Hsuan, Naesens, Lieve, Edstein, Michael D, Chavchich, Marina, Guddat, Luke W
Published in Journal of medicinal chemistry (22.01.2015)

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Helicobacter pylori Xanthine–Guanine–Hypoxanthine PhosphoribosyltransferaseA Putative Target for Drug Discovery against Gastrointestinal Tract Infections

Helicobacter pylori Xanthine–Guanine–Hypoxanthine PhosphoribosyltransferaseA Putative Target for Drug Discovery against Gastrointestinal Tract Infections

by Keough, Dianne T, Wun, Shun Jie, Baszczyňski, Ondřej, Eng, Wai Soon, Špaček, Petr, Panjikar, Santosh, Naesens, Lieve, Pohl, Radek, Rejman, Dominik, Hocková, Dana, Ferrero, Richard L, Guddat, Luke W
Published in Journal of medicinal chemistry (13.05.2021)

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Synthesis of Novel N-Branched Acyclic Nucleoside Phosphonates As Potent and Selective Inhibitors of Human, Plasmodium falciparum and Plasmodium vivax 6-Oxopurine Phosphoribosyltransferases

Synthesis of Novel N-Branched Acyclic Nucleoside Phosphonates As Potent and Selective Inhibitors of Human, Plasmodium falciparum and Plasmodium vivax 6-Oxopurine Phosphoribosyltransferases

by Hocková, Dana, Keough, Dianne T, Janeba, Zlatko, Wang, Tzu-Hsuan, de Jersey, John, Guddat, Luke W
Published in Journal of medicinal chemistry (12.07.2012)

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Synthesis and anti-trypanosomal evaluation of novel N-branched acyclic nucleoside phosphonates bearing 7-aryl-7-deazapurine nucleobase

Synthesis and anti-trypanosomal evaluation of novel N-branched acyclic nucleoside phosphonates bearing 7-aryl-7-deazapurine nucleobase

by Vankova, Karolina, Dolezelova, Eva, Tloustova, Eva, Hockova, Dana, Zikova, Alena, Janeba, Zlatko
Published in European journal of medicinal chemistry (05.09.2022)

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Novel nucleotide analogues bearing (1H-1,2,3-triazol-4-yl)phosphonic acid moiety as inhibitors of Plasmodium and human 6-oxopurine phosphoribosyltransferases

Novel nucleotide analogues bearing (1H-1,2,3-triazol-4-yl)phosphonic acid moiety as inhibitors of Plasmodium and human 6-oxopurine phosphoribosyltransferases

by Lukáč, Miloš, Hocková, Dana, Keough, Dianne T., Guddat, Luke W., Janeba, Zlatko
Published in Tetrahedron (09.02.2017)

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Crystal structures of Trypanosoma brucei hypoxanthine – guanine – xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP

Crystal structures of Trypanosoma brucei hypoxanthine – guanine – xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP

by Terán, David, Doleželová, Eva, Keough, Dianne T., Hocková, Dana, Zíková, Alena, Guddat, Luke W.
Published in The FEBS journal (01.12.2019)

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N2′‐Branched Acyclic Nucleoside Phosphonates Containing 9‐Deazahypoxanthine as Inhibitors of Plasmodium falciparum 6‐Oxopurine Phosphoribosyltransferase

N2′‐Branched Acyclic Nucleoside Phosphonates Containing 9‐Deazahypoxanthine as Inhibitors of Plasmodium falciparum 6‐Oxopurine Phosphoribosyltransferase

by Vaňková, Karolína, Keough, Dianne T., Hocková, Dana, Guddat, Luke W., Janeba, Zlatko
Published in ChemMedChem (01.08.2023)

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First Crystal Structures of Mycobacterium tuberculosis 6‑Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity

First Crystal Structures of Mycobacterium tuberculosis 6‑Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity

by Eng, Wai Soon, Hocková, Dana, Špaček, Petr, Janeba, Zlatko, West, Nicholas P, Woods, Kyra, Naesens, Lieve M. J, Keough, Dianne T, Guddat, Luke W
Published in Journal of medicinal chemistry (11.06.2015)

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Acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group Are Potent Inhibitors of 6‑Oxopurine Phosphoribosyltransferases and Have Antimalarial Activity

Acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group Are Potent Inhibitors of 6‑Oxopurine Phosphoribosyltransferases and Have Antimalarial Activity

by Keough, Dianne T, Špaček, Petr, Hocková, Dana, Tichý, Tomáš, Vrbková, Silvie, Slavětínská, Lenka, Janeba, Zlatko, Naesens, Lieve, Edstein, Michael D, Chavchich, Marina, Wang, Tzu-Hsuan, de Jersey, John, Guddat, Luke W
Published in Journal of medicinal chemistry (28.03.2013)

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Nucleotide analogues containing a pyrrolidine, piperidine or piperazine ring: Synthesis and evaluation of inhibition of plasmodial and human 6-oxopurine phosphoribosyltransferases and in vitro antimalarial activity

Nucleotide analogues containing a pyrrolidine, piperidine or piperazine ring: Synthesis and evaluation of inhibition of plasmodial and human 6-oxopurine phosphoribosyltransferases and in vitro antimalarial activity

by Frydrych, Jan, Keough, Dianne T., Chavchich, Marina, Travis, Jye, Dračínský, Martin, Edstein, Michael D., Guddat, Luke W., Hocková, Dana, Janeba, Zlatko
Published in European journal of medicinal chemistry (05.07.2021)

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Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery

Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery

by Doleželová, Eva, Terán, David, Gahura, Ondřej, Kotrbová, Zuzana, Procházková, Michaela, Keough, Dianne, Špaček, Petr, Hocková, Dana, Guddat, Luke, Zíková, Alena
Published in PLoS neglected tropical diseases (26.02.2018)

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Synthesis and Evaluation of Asymmetric Acyclic Nucleoside Bisphosphonates as Inhibitors of Plasmodium falciparum and Human Hypoxanthine–Guanine–(Xanthine) Phosphoribosyltransferase

Synthesis and Evaluation of Asymmetric Acyclic Nucleoside Bisphosphonates as Inhibitors of Plasmodium falciparum and Human Hypoxanthine–Guanine–(Xanthine) Phosphoribosyltransferase

by Špaček, Petr, Keough, Dianne T, Chavchich, Marina, Dračínský, Martin, Janeba, Zlatko, Naesens, Lieve, Edstein, Michael D, Guddat, Luke W, Hocková, Dana
Published in Journal of medicinal chemistry (14.09.2017)

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C1′-Branched acyclic nucleoside phosphonates mimicking adenosine monophosphate: Potent inhibitors of Trypanosoma brucei adenine phosphoribosyltransferase

C1′-Branched acyclic nucleoside phosphonates mimicking adenosine monophosphate: Potent inhibitors of Trypanosoma brucei adenine phosphoribosyltransferase

by Kalčic, Filip, Frydrych, Jan, Doleželová, Eva, Slapničková, Martina, Pachl, Petr, Slavětínská, Lenka Poštová, Dračínský, Martin, Hocková, Dana, Zíková, Alena, Janeba, Zlatko
Published in European journal of medicinal chemistry (05.12.2021)

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Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase by Acyclic Nucleoside Phosphonates: A New Class of Antimalarial Therapeutics

Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase by Acyclic Nucleoside Phosphonates: A New Class of Antimalarial Therapeutics

by Keough, Dianne T, Hocková, Dana, Holý, Antonín, Naesens, Lieve M. J, Skinner-Adams, Tina S, Jersey, John de, Guddat, Luke W
Published in Journal of medicinal chemistry (23.07.2009)

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