Search Results - "Hockerman, Susan L" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of (3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy

Discovery of (3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2H-benzo[g]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy

by Meyers, Marvin J, Arhancet, Graciela B, Hockerman, Susan L, Chen, Xiangyang, Long, Scott A, Mahoney, Matthew W, Rico, Joseph R, Garland, Danny J, Blinn, James. R, Collins, Joe T, Yang, Shengtian, Huang, Horng-Chih, McGee, Kevin F, Wendling, Jay M, Dietz, Jessica D, Payne, Maria A, Homer, Bruce L, Heron, Marcia I, Reitz, David B, Hu, Xiao
Published in Journal of medicinal chemistry (26.08.2010)

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Journal Article

MMP-13 selective isonipecotamide α-sulfone hydroxamates

MMP-13 selective isonipecotamide α-sulfone hydroxamates

by Kolodziej, Stephen A., Hockerman, Susan L., DeCrescenzo, Gary A., McDonald, Joseph J., Mischke, Debbie A., Munie, Grace E., Fletcher, Theresa R., Stehle, Nathan, Swearingen, Craig, Becker, Daniel P.
Published in Bioorganic & medicinal chemistry letters (15.06.2010)

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Journal Article

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

by HOCKERMAN SUSAN L, MONAHAN JOSEPH B, SELNESS SHAUN R
Year of Publication 01.12.2022

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Patent

Orally bioavailable dual MMP-1/MMP-14 sparing, MMP-13 selective α-sulfone hydroxamates

Orally bioavailable dual MMP-1/MMP-14 sparing, MMP-13 selective α-sulfone hydroxamates

by Kolodziej, Stephen A., Hockerman, Susan L., Boehm, Terri L., Carroll, Jeffery N., DeCrescenzo, Gary A., McDonald, Joseph J., Mischke, Debbie A., Munie, Grace E., Fletcher, Theresa R., Rico, Joseph G., Stehle, Nathan W., Swearingen, Craig, Becker, Daniel P.
Published in Bioorganic & medicinal chemistry letters (15.06.2010)

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Journal Article

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

by HOCKERMAN SUSAN L, MONAHAN JOSEPH B, SELNESS SHAUN R
Year of Publication 19.10.2021

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Patent

MMP-13 selective α-sulfone hydroxamates: A survey of P1′ heterocyclic amide isosteres

MMP-13 selective α-sulfone hydroxamates: A survey of P1′ heterocyclic amide isosteres

by Barta, Thomas E., Becker, Daniel P., Bedell, Louis J., Easton, Alan M., Hockerman, Susan L., Kiefer, James, Munie, Grace E., Mathis, Karl J., Li, Madeleine H., Rico, Joseph G., Villamil, Clara I., Williams, Jennifer M.
Published in Bioorganic & medicinal chemistry letters (15.05.2011)

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Journal Article

Chemical Library Purification Strategies Based on Principles of Complementary Molecular Reactivity and Molecular Recognition

Chemical Library Purification Strategies Based on Principles of Complementary Molecular Reactivity and Molecular Recognition

by Flynn, Daniel L, Crich, Joyce Z, Devraj, Rajesh V, Hockerman, Susan L, Parlow, John J, South, Michael S, Woodard, Scott
Published in Journal of the American Chemical Society (28.05.1997)

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Journal Article

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

by HOCKERMAN SUSAN L, MONAHAN JOSEPH B, SELNESS SHAUN R
Year of Publication 15.02.2016

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Patent

α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1

α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1

by Becker, Daniel P, Barta, Thomas E, Bedell, Louis, DeCrescenzo, Gary, Freskos, John, Getman, Daniel P, Hockerman, Susan L, Li, Madeleine, Mehta, Pramod, Mischke, Brent, Munie, Grace E, Swearingen, Craig, Villamil, Clara I
Published in Bioorganic & medicinal chemistry letters (22.10.2001)

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Journal Article

SUBSTITUTED PYROOLOPYRIDINES AND PYRROLOPYRAZINES FOR TREATING CANCER OR INFLAMMATORY DISEASES

SUBSTITUTED PYROOLOPYRIDINES AND PYRROLOPYRAZINES FOR TREATING CANCER OR INFLAMMATORY DISEASES

by JACOBSEN ERIC JON, HOCKERMAN SUSAN L, SPRINGER JOHN ROBERT, BLINN JAMES ROBERT
Year of Publication 05.09.2016

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Patent

α-Alkyl-α-amino-β-sulphone hydroxamates as potent MMP inhibitors that spare MMP-1

α-Alkyl-α-amino-β-sulphone hydroxamates as potent MMP inhibitors that spare MMP-1

by Becker, Daniel P, DeCrescenzo, Gary, Freskos, John, Getman, Daniel P, Hockerman, Susan L, Li, Madeleine, Mehta, Pramod, Munie, Grace E, Swearingen, Craig
Published in Bioorganic & medicinal chemistry letters (22.10.2001)

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Journal Article

Discovery of (3 S ,3a R )-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2 H -benzo[ g ]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy

Discovery of (3 S ,3a R )-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydro-2 H -benzo[ g ]indazole-7-carboxylic Acid (PF-3882845), an Orally Efficacious Mineralocorticoid Receptor (MR) Antagonist for Hypertension and Nephropathy

by Meyers, Marvin J., Arhancet, Graciela B., Hockerman, Susan L., Chen, Xiangyang, Long, Scott A., Mahoney, Matthew W., Rico, Joseph R., Garland, Danny J., Blinn, James. R., Collins, Joe T., Yang, Shengtian, Huang, Horng-Chih, McGee, Kevin F., Wendling, Jay M., Dietz, Jessica D., Payne, Maria A., Homer, Bruce L., Heron, Marcia I., Reitz, David B., Hu, Xiao
Published in Journal of medicinal chemistry (26.08.2010)

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Journal Article

Aromatic sulfone hydroxamates and their use as protease inhibitors

Aromatic sulfone hydroxamates and their use as protease inhibitors

by FRESKOS JOHN N.,FOBIAN YVETTE M.,BARTA THOMAS E.,BECKER DANIEL P.,BEDELL LOUIS J.,BOEHM TERRI L.,HOCKERMAN SUSAN L.,KASSAB DARREN J.,KOLODZIEJ STEVE A.,MCDONALD JOSEPH,NORTON MONICA B.,RICO JOSEPH G, JUAN JANE
Year of Publication 26.04.2006

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Patent

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

by SELNESS, SHAUN R, HOCKERMAN, SUSAN L, MONAHAN, JOSEPH B
Year of Publication 25.10.2021

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Patent

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

by SELNESS, SHAUN R, HOCKERMAN, SUSAN L, MONAHAN, JOSEPH B
Year of Publication 07.09.2021

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Patent

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

by SELNESS Shaun R, HOCKERMAN Susan L, MONAHAN Joseph B
Year of Publication 31.08.2021

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Patent

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

by HOCKERMAN, Susan, L, SELNESS, Shaun, R, MONAHAN, Joseph, B
Year of Publication 07.07.2021

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Patent

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

by Monahan, Joseph B, Hockerman, Susan L, Selness, Shaun R
Year of Publication 25.06.2021

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Patent

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

METHYL/FLUORO-PYRIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS AND FLUORO-PYRIMIDINYL-METHOXY SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS

by HOCKERMAN, SUSAN, L, SELNESS, SHAUN, R, MONAHAN, JOSEPH, B
Year of Publication 31.05.2021

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Patent

METHYL/FLUOR-PYRIDINYL-METOXY-SUBSTITUEREDE PYRIDINON-PYRIDINYL-FORBINDELSER OG FLUOR-PYRIMIDINYL-METOXY-SUBSTITUEREDE PYRIDINON-PYRIDINYL-FORBINDELSER

METHYL/FLUOR-PYRIDINYL-METOXY-SUBSTITUEREDE PYRIDINON-PYRIDINYL-FORBINDELSER OG FLUOR-PYRIMIDINYL-METOXY-SUBSTITUEREDE PYRIDINON-PYRIDINYL-FORBINDELSER

by HOCKERMAN, Susan, L, SELNESS, Shaun, R, MONAHAN, Joseph, B
Year of Publication 25.05.2021

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Patent

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