Staphylococcus aureus alpha-toxin mediates general and cell type-specific changes in metabolite concentrations of immortalized human airway epithelial cells
Gierok, Philipp, Harms, Manuela, Richter, Erik, Hildebrandt, Jan-Peter, Lalk, Michael, Mostertz, Jörg, Hochgräfe, Falko
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Nitric Oxide Stress Induces Different Responses but Mediates Comparable Protein Thiol Protection in Bacillus subtilis and Staphylococcus aureus
HOCHGRÄFE, Falko, WOLF, Carmen, FUCHS, Stephan, LIEBEKE, Manuel, LALK, Michael, ENGELMANN, Susanne, HECKER, Michael
Published in Journal of Bacteriology (01.07.2008)
Published in Journal of Bacteriology (01.07.2008)
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Phosphoproteomic analysis of anaplastic lymphoma kinase (ALK) downstream signaling pathways identifies signal transducer and activator of transcription 3 as a functional target of activated ALK in neuroblastoma cells
Sattu, Kamaraj, Hochgräfe, Falko, Wu, Jianmin, Umapathy, Ganesh, Schönherr, Christina, Ruuth, Kristina, Chand, Damini, Witek, Barbara, Fuchs, James, Li, Pui‐Kai, Hugosson, Fredrik, Daly, Roger J., Palmer, Ruth H., Hallberg, Bengt
Published in The FEBS journal (01.11.2013)
Published in The FEBS journal (01.11.2013)
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Journal Article
Diamide Triggers Mainly S Thiolations in the Cytoplasmic Proteomes of Bacillus subtilis and Staphylococcus aureus
PÖTHER, Dierk-Christoph, LIEBEKE, Manuel, HECKER, Michael, HOCHGRÄFE, Falko, ANTELMANN, Haike, BECHER, Dörte, LALK, Michael, LINDEQUIST, Ulrike, BOROVOK, Ilya, COHEN, Gerald, AHARONOWITZ, Yair
Published in Journal of Bacteriology (01.12.2009)
Published in Journal of Bacteriology (01.12.2009)
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Journal Article
Tyrosine Phosphorylation Profiling Reveals the Signaling Network Characteristics of Basal Breast Cancer Cells
HOCHGRÄFE, Falko, LUXI ZHANG, SHEARER, Robert, NAIR, Radhika, SWARBRICK, Alexander, FARATIAN, Dana, MULLEN, Peter, HARRISON, David J, BIANKIN, Andrew V, SUTHERLAND, Robert L, RAFTERY, Mark J, DALY, Roger J, O'TOOLE, Sandra A, BROWNE, Brigid C, PINESE, Mark, PORTA CUBAS, Ana, LEHRBACH, Gillian M, CROUCHER, David R, RICKWOOD, Danny, BOULGHOURJIAN, Alice
Published in Cancer research (Chicago, Ill.) (15.11.2010)
Published in Cancer research (Chicago, Ill.) (15.11.2010)
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Journal Article
Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling
Humphrey, Emily S., Su, Shih-Ping, Nagrial, Adnan M., Hochgräfe, Falko, Pajic, Marina, Lehrbach, Gillian M., Parton, Robert G., Yap, Alpha S., Horvath, Lisa G., Chang, David K., Biankin, Andrew V., Wu, Jianmin, Daly, Roger J.
Published in Molecular & cellular proteomics (01.08.2016)
Published in Molecular & cellular proteomics (01.08.2016)
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Involvement of Lyn and the Atypical Kinase SgK269/PEAK1 in a Basal Breast Cancer Signaling Pathway
CROUCHER, David R, HOCHGRÄFE, Falko, SHEARER, Robert, GALLEGO-ORTEGA, David, SAUNDERS, Darren N, SWARBRICK, Alexander, DALY, Roger J, LUXI ZHANG, LING LIU, LYONS, Ruth J, RICKWOOD, Danny, TACTACAN, Carole M, BROWNE, Brigid C, ALI, Naveid, CHAN, Howard
Published in Cancer research (Chicago, Ill.) (15.03.2013)
Published in Cancer research (Chicago, Ill.) (15.03.2013)
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Journal Article
Quantitative Proteomics Reveals the Dynamics of Protein Phosphorylation in Human Bronchial Epithelial Cells during Internalization, Phagosomal Escape, and Intracellular Replication of Staphylococcus aureus
Richter, Erik, Harms, Manuela, Ventz, Katharina, Nölker, Rolf, Fraunholz, Martin J, Mostertz, Jörg, Hochgräfe, Falko
Published in Journal of proteome research (02.12.2016)
Published in Journal of proteome research (02.12.2016)
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Journal Article
Proteomic discovery of host kinase signaling in bacterial infections
Richter, Erik, Mostertz, Jörg, Hochgräfe, Falko
Published in Proteomics. Clinical applications (01.10.2016)
Published in Proteomics. Clinical applications (01.10.2016)
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Journal Article
GvmR - A Novel LysR-Type Transcriptional Regulator Involved in Virulence and Primary and Secondary Metabolism of Burkholderia pseudomallei
Duong, Linh Tuan, Schwarz, Sandra, Gross, Harald, Breitbach, Katrin, Hochgräfe, Falko, Mostertz, Jörg, Eske-Pogodda, Kristin, Wagner, Gabriel E, Steinmetz, Ivo, Kohler, Christian
Published in Frontiers in microbiology (16.05.2018)
Published in Frontiers in microbiology (16.05.2018)
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A multi-omics approach identifies key hubs associated with cell type-specific responses of airway epithelial cells to staphylococcal alpha-toxin
Richter, Erik, Harms, Manuela, Ventz, Katharina, Gierok, Philipp, Chilukoti, Ravi Kumar, Hildebrandt, Jan-Peter, Mostertz, Jörg, Hochgräfe, Falko
Published in PloS one (27.03.2015)
Published in PloS one (27.03.2015)
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Characterization of the Novel Broad-Spectrum Kinase Inhibitor CTx-0294885 As an Affinity Reagent for Mass Spectrometry-Based Kinome Profiling
Zhang, Luxi, Holmes, Ian P, Hochgräfe, Falko, Walker, Scott R, Ali, Naveid A, Humphrey, Emily S, Wu, Jianmin, de Silva, Melanie, Kersten, Wilhelmus J. A, Connor, Theresa, Falk, Hendrik, Allan, Lynda, Street, Ian P, Bentley, John D, Pilling, Patricia A, Monahan, Brendon J, Peat, Thomas S, Daly, Roger J
Published in Journal of proteome research (05.07.2013)
Published in Journal of proteome research (05.07.2013)
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Journal Article
Global characterization of signalling networks associated with tamoxifen resistance in breast cancer
Browne, Brigid C, Hochgräfe, Falko, Wu, Jianmin, Millar, Ewan K. A, Barraclough, Jane, Stone, Andrew, McCloy, Rachael A, Lee, Christine S, Roberts, Caroline, Ali, Naveid A, Boulghourjian, Alice, Schmich, Fabian, Linding, Rune, Farrow, Lynn, Gee, Julia M. W, Nicholson, Robert I, O'Toole, Sandra A, Sutherland, Robert L, Musgrove, Elizabeth A, Butt, Alison J, Daly, Roger J
Published in The FEBS journal (01.11.2013)
Published in The FEBS journal (01.11.2013)
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Quantitative phosphotyrosine profiling of patient-derived xenografts identifies therapeutic targets in pediatric leukemia
Dolai, Sibasish, Sia, Keith C S, Robbins, Alissa K, Zhong, Ling, Heatley, Sue L, Vincent, Tiffaney L, Hochgräfe, Falko, Sutton, Rosemary, Kurmasheva, Raushan T, Revesz, Tamas, White, Deborah L, Houghton, Peter J, Smith, Malcolm A, Teachey, David T, Daly, Roger J, Raftery, Mark J, Lock, Richard B
Published in Cancer research (Chicago, Ill.) (01.05.2016)
Published in Cancer research (Chicago, Ill.) (01.05.2016)
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Journal Article
S-Cysteinylation Is a General Mechanism for Thiol Protection of Bacillus subtilis Proteins after Oxidative Stress
Hochgräfe, Falko, Mostertz, Jörg, Pöther, Dierk-Christoph, Becher, Dörte, Helmann, John D., Hecker, Michael
Published in The Journal of biological chemistry (07.09.2007)
Published in The Journal of biological chemistry (07.09.2007)
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Journal Article
Comprehensive Redox Profiling of the Thiol Proteome of Clostridium difficile
Sievers, Susanne, Dittmann, Silvia, Jordt, Tim, Otto, Andreas, Hochgräfe, Falko, Riedel, Katharina
Published in Molecular & cellular proteomics (01.05.2018)
Published in Molecular & cellular proteomics (01.05.2018)
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Journal Article
Redox regulation of mitochondrial proteins and proteomes by cysteine thiol switches
Nietzel, Thomas, Mostertz, Jörg, Hochgräfe, Falko, Schwarzländer, Markus
Published in Mitochondrion (01.03.2017)
Published in Mitochondrion (01.03.2017)
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Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination
Nietzel, Thomas, Mostertz, Jörg, Ruberti, Cristina, Née, Guillaume, Fuchs, Philippe, Wagner, Stephan, Moseler, Anna, Müller-Schüssele, Stefanie J., Benamar, Abdelilah, Poschet, Gernot, Büttner, Michael, Møller, Ian Max, Lillig, Christopher H., Macherel, David, Wirtz, Markus, Hell, Rüdiger, Finkemeier, Iris, Meyer, Andreas J., Hochgräfe, Falko, Schwarzländer, Markus
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2020)
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