Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State
Garcia-Cao, Isabel, Song, Min Sup, Hobbs, Robin M., Laurent, Gaelle, Giorgi, Carlotta, de Boer, Vincent C.J., Anastasiou, Dimitrios, Ito, Keisuke, Sasaki, Atsuo T., Rameh, Lucia, Carracedo, Arkaitz, Vander Heiden, Matthew G., Cantley, Lewis C., Pinton, Paolo, Haigis, Marcia C., Pandolfi, Pier Paolo
Published in Cell (30.03.2012)
Published in Cell (30.03.2012)
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Journal Article
Plzf Regulates Germline Progenitor Self-Renewal by Opposing mTORC1
Hobbs, Robin M., Seandel, Marco, Falciatori, Ilaria, Rafii, Shahin, Pandolfi, Pier Paolo
Published in Cell (06.08.2010)
Published in Cell (06.08.2010)
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Journal Article
Cancer-Associated PTEN Mutants Act in a Dominant-Negative Manner to Suppress PTEN Protein Function
Papa, Antonella, Wan, Lixin, Bonora, Massimo, Salmena, Leonardo, Song, Min Sup, Hobbs, Robin M., Lunardi, Andrea, Webster, Kaitlyn, Ng, Christopher, Newton, Ryan H., Knoblauch, Nicholas, Guarnerio, Jlenia, Ito, Keisuke, Turka, Laurence A., Beck, Andy H., Pinton, Paolo, Bronson, Roderick T., Wei, Wenyi, Pandolfi, Pier Paolo
Published in Cell (24.04.2014)
Published in Cell (24.04.2014)
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Journal Article
Functional Antagonism between Sall4 and Plzf Defines Germline Progenitors
Hobbs, Robin M., Fagoonee, Sharmila, Papa, Antonella, Webster, Kaitlyn, Altruda, Fiorella, Nishinakamura, Ryuichi, Chai, Li, Pandolfi, Pier Paolo
Published in Cell stem cell (02.03.2012)
Published in Cell stem cell (02.03.2012)
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Journal Article
DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia
Legrand, Julien M D, Chan, Ai-Leen, La, Hue M, Rossello, Fernando J, Änkö, Minna-Liisa, Fuller-Pace, Frances V, Hobbs, Robin M
Published in Nature communications (23.05.2019)
Published in Nature communications (23.05.2019)
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Journal Article
RNA processing in the male germline: Mechanisms and implications for fertility
Legrand, Julien M.D., Hobbs, Robin M.
Published in Seminars in cell & developmental biology (01.07.2018)
Published in Seminars in cell & developmental biology (01.07.2018)
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Journal Article
Identification of dynamic undifferentiated cell states within the male germline
La, Hue M, Mäkelä, Juho-Antti, Chan, Ai-Leen, Rossello, Fernando J, Nefzger, Christian M, Legrand, Julien M D, De Seram, Mia, Polo, Jose M, Hobbs, Robin M
Published in Nature communications (19.07.2018)
Published in Nature communications (19.07.2018)
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Journal Article
Revealing cellular and molecular transitions in neonatal germ cell differentiation using single cell RNA sequencing
Liao, Jinyue, Ng, Shuk Han, Luk, Alfred Chun, Suen, Hoi Ching, Qian, Yan, Lee, Annie Wing Tung, Tu, Jiajie, Fung, Jacqueline Chak Lam, Tang, Nelson Leung Sang, Feng, Bo, Chan, Wai Yee, Fouchet, Pierre, Hobbs, Robin M, Lee, Tin Lap
Published in Development (Cambridge) (27.03.2019)
Published in Development (Cambridge) (27.03.2019)
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Journal Article
Long-Term Maintenance and Meiotic Entry of Early Germ Cells in Murine Testicular Organoids Functionalized by 3D Printed Scaffolds and Air-Medium Interface Cultivation
Richer, Guillaume, Hobbs, Robin M, Loveland, Katherine L, Goossens, Ellen, Baert, Yoni
Published in Frontiers in physiology (24.12.2021)
Published in Frontiers in physiology (24.12.2021)
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Journal Article
GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance
La, Hue M, Chan, Ai-Leen, Legrand, Julien M D, Rossello, Fernando J, Gangemi, Christina G, Papa, Antonella, Cheng, Qiang, Morand, Eric F, Hobbs, Robin M
Published in Development (Cambridge) (18.09.2018)
Published in Development (Cambridge) (18.09.2018)
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Journal Article
Distinctive molecular features of regenerative stem cells in the damaged male germline
La, Hue M, Liao, Jinyue, Legrand, Julien M D, Rossello, Fernando J, Chan, Ai-Leen, Vaghjiani, Vijesh, Cain, Jason E, Papa, Antonella, Lee, Tin Lap, Hobbs, Robin M
Published in Nature communications (06.05.2022)
Published in Nature communications (06.05.2022)
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Journal Article
SOX3 promotes generation of committed spermatogonia in postnatal mouse testes
McAninch, Dale, Mäkelä, Juho-Antti, La, Hue M, Hughes, James N, Lovell-Badge, Robin, Hobbs, Robin M, Thomas, Paul Q
Published in Scientific reports (21.04.2020)
Published in Scientific reports (21.04.2020)
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Journal Article
Distinct germline progenitor subsets defined through Tsc2-mTORC1 signaling
Hobbs, Robin M, La, Hue M, Mäkelä, Juho-Antti, Kobayashi, Toshiyuki, Noda, Tetsuo, Pandolfi, Pier Paolo
Published in EMBO reports (01.04.2015)
Published in EMBO reports (01.04.2015)
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Journal Article
Generation of functional multipotent adult stem cells from GPR125 + germline progenitors
Falciatori, Ilaria, Yancopoulos, George D, Rafii, Shahin, Gale, Nicholas W, Hobbs, Robin M, Valenzuela, David M, James, Daylon, Torres, Richard, Zhang, Fan, Murphy, Andrew, Kim, Jiyeon, Shmelkov, Sergey V, Chavala, Sai, Scherr, Douglas S, Pandolfi, Pier Paolo, Seandel, Marco
Published in Nature (London) (20.09.2007)
Published in Nature (London) (20.09.2007)
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Journal Article
Repression of kit Expression by Plzf in Germ Cells
Filipponi, Doria, Hobbs, Robin M., Ottolenghi, Sergio, Rossi, Pellegrino, Jannini, Emmanuele A., Pandolfi, Pier Paolo, Dolci, Susanna
Published in Molecular and Cellular Biology (01.10.2007)
Published in Molecular and Cellular Biology (01.10.2007)
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Journal Article
Essential role of Plzf in maintenance of spermatogonial stem cells
Pandolfi, Pier Paolo, Hobbs, Robin M, Manova, Katia, Sukhwani, Meena, Barna, Maria, Cattoretti, Giorgio, Orwig, Kyle E, Wolgemuth, Debra J, Costoya, José A
Published in Nature genetics (01.06.2004)
Published in Nature genetics (01.06.2004)
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Journal Article
Germline Stem Cell Activity Is Sustained by SALL4-Dependent Silencing of Distinct Tumor Suppressor Genes
Chan, Ai-Leen, La, Hue M., Legrand, Julien M.D., Mäkelä, Juho-Antti, Eichenlaub, Michael, De Seram, Mia, Ramialison, Mirana, Hobbs, Robin M.
Published in Stem cell reports (12.09.2017)
Published in Stem cell reports (12.09.2017)
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Journal Article
The single-cell chromatin accessibility landscape in mouse perinatal testis development
Suen, Hoi Ching, Rao, Shitao, Luk, Alfred Chun Shui, Zhang, Ruoyu, Yang, Lele, Qi, Huayu, So, Hon Cheong, Hobbs, Robin M, Lee, Tin-Lap, Liao, Jinyue
Published in eLife (25.04.2023)
Published in eLife (25.04.2023)
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Journal Article
AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans
Houston, Brendan J., Nguyen, Joseph, Merriner, D. Jo, O’Connor, Anne E., Lopes, Alexandra M., Nagirnaja, Liina, Friedrich, Corinna, Kliesch, Sabine, Tüttelmann, Frank, Aston, Kenneth I., Conrad, Donald F., Hobbs, Robin M., Dunleavy, Jessica E. M., O’Bryan, Moira K.
Published in Cell death & disease (12.07.2024)
Published in Cell death & disease (12.07.2024)
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Journal Article