Human Fatty Liver Disease: Old Questions and New Insights
Cohen, Jonathan C., Horton, Jay D., Hobbs, Helen H.
Published in Science (American Association for the Advancement of Science) (24.06.2011)
Published in Science (American Association for the Advancement of Science) (24.06.2011)
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Journal Article
PNPLA3, CGI‐58, and Inhibition of Hepatic Triglyceride Hydrolysis in Mice
Wang, Yang, Kory, Nora, BasuRay, Soumik, Cohen, Jonathan C, Hobbs, Helen H
Published in Hepatology (Baltimore, Md.) (01.06.2019)
Published in Hepatology (Baltimore, Md.) (01.06.2019)
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Journal Article
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
Cohen, Jonathan C, Hobbs, Helen H, Romeo, Stefano, Kozlitina, Julia, Xing, Chao, Pertsemlidis, Alexander, Cox, David, Pennacchio, Len A, Boerwinkle, Eric
Published in Nature genetics (01.12.2008)
Published in Nature genetics (01.12.2008)
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Journal Article
PCSK9: a convertase that coordinates LDL catabolism
Horton, Jay D., Cohen, Jonathan C., Hobbs, Helen H.
Published in Journal of lipid research (01.04.2009)
Published in Journal of lipid research (01.04.2009)
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Journal Article
Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion
Wang, Yan, Gusarova, Viktoria, Banfi, Serena, Gromada, Jesper, Cohen, Jonathan C, Hobbs, Helen H
Published in Journal of lipid research (01.07.2015)
Published in Journal of lipid research (01.07.2015)
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Journal Article
Pnpla3I148M knockin mice accumulate PNPLA3 on lipid droplets and develop hepatic steatosis
Smagris, Eriks, BasuRay, Soumik, Li, John, Huang, Yongcheng, Lai, Ka‐man V., Gromada, Jesper, Cohen, Jonathan C., Hobbs, Helen H.
Published in Hepatology (Baltimore, Md.) (01.01.2015)
Published in Hepatology (Baltimore, Md.) (01.01.2015)
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Journal Article
Atypical angiopoietin-like protein that regulates ANGPTL3
Quagliarini, Fabiana, Wang, Yan, Kozlitina, Julia, Grishin, Nick V, Hyde, Rhonda, Boerwinkle, Eric, Valenzuela, David M, Murphy, Andrew J, Cohen, Jonathan C, Hobbs, Helen H
Published in Proceedings of the National Academy of Sciences - PNAS (27.11.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (27.11.2012)
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Journal Article
Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis
Wang, Yan, Quagliarini, Fabiana, Gusarova, Viktoria, Gromada, Jesper, Valenzuela, David M., Cohen, Jonathan C., Hobbs, Helen H.
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (01.10.2013)
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Journal Article
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans
Romeo, Stefano, Yin, Wu, Kozlitina, Julia, Pennacchio, Len A, Boerwinkle, Eric, Hobbs, Helen H, Cohen, Jonathan C
Published in The Journal of clinical investigation (01.01.2009)
Published in The Journal of clinical investigation (01.01.2009)
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Journal Article
Crystal structure of the human sterol transporter ABCG5/ABCG8
Lee, Jyh-Yeuan, Kinch, Lisa N., Borek, Dominika M., Wang, Jin, Wang, Junmei, Urbatsch, Ina L., Xie, Xiao-Song, Grishin, Nikolai V., Cohen, Jonathan C., Otwinowski, Zbyszek, Hobbs, Helen H., Rosenbaum, Daniel M.
Published in Nature (London) (26.05.2016)
Published in Nature (London) (26.05.2016)
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Journal Article
ANGPTL8/Betatrophin Does Not Control Pancreatic Beta Cell Expansion
Gusarova, Viktoria, Alexa, Corey A., Na, Erqian, Stevis, Panayiotis E., Xin, Yurong, Bonner-Weir, Susan, Cohen, Jonathan C., Hobbs, Helen H., Murphy, Andrew J., Yancopoulos, George D., Gromada, Jesper
Published in Cell (23.10.2014)
Published in Cell (23.10.2014)
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Journal Article
A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
He, Shaoqing, McPhaul, Christopher, Li, John Zhong, Garuti, Rita, Kinch, Lisa, Grishin, Nick V., Cohen, Jonathan C., Hobbs, Helen H.
Published in The Journal of biological chemistry (26.02.2010)
Published in The Journal of biological chemistry (26.02.2010)
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Journal Article
Hepatic ANGPTL3 regulates adipose tissue energy homeostasis
Wang, Yan, McNutt, Markey C., Banfi, Serena, Levin, Michael G., Holland, William L., Gusarova, Viktoria, Gromada, Jesper, Cohen, Jonathan C., Hobbs, Helen H.
Published in Proceedings of the National Academy of Sciences - PNAS (15.09.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (15.09.2015)
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Journal Article
Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways
Mitsche, Matthew A, McDonald, Jeffrey G, Hobbs, Helen H, Cohen, Jonathan C
Published in eLife (26.06.2015)
Published in eLife (26.06.2015)
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Journal Article
Genetic and Metabolic Determinants of Plasma PCSK9 Levels
Lakoski, Susan G, Lagace, Thomas A, Cohen, Jonathan C, Horton, Jay D, Hobbs, Helen H
Published in The journal of clinical endocrinology and metabolism (01.07.2009)
Published in The journal of clinical endocrinology and metabolism (01.07.2009)
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Journal Article
Relative roles of ABCG5/ABCG8 in liver and intestine[S]
Wang, Jin, Mitsche, Matthew A., Lütjohann, Dieter, Cohen, Jonathan C., Xie, Xiao-Song, Hobbs, Helen H.
Published in Journal of lipid research (01.02.2015)
Published in Journal of lipid research (01.02.2015)
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