Thirty Years of HDAC Inhibitors: 2020 Insight and Hindsight
Ho, Terence C. S, Chan, Alex H. Y, Ganesan, A
Published in Journal of medicinal chemistry (12.11.2020)
Published in Journal of medicinal chemistry (12.11.2020)
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Journal Article
Synthesis of pyrrothiamine, a novel thiamine analogue, and evaluation of derivatives as potent and selective inhibitors of pyruvate dehydrogenase
Chan, Alex H. Y, Ho, Terence C. S, Agyei-Owusu, Kwasi, Leeper, Finian J
Published in Organic & biomolecular chemistry (23.11.2022)
Published in Organic & biomolecular chemistry (23.11.2022)
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Journal Article
Open-chain thiamine analogues as potent inhibitors of thiamine pyrophosphate (TPP)-dependent enzymes
Chan, Alex H. Y, Ho, Terence C. S, Leeper, Finian J
Published in Organic & biomolecular chemistry (16.08.2023)
Published in Organic & biomolecular chemistry (16.08.2023)
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Journal Article
Correction: Thiamine analogues as inhibitors of pyruvate dehydrogenase and discovery of a thiamine analogue with non-thiamine related antiplasmodial activity
Chan, Alex H. Y, Fathoni, Imam, Ho, Terence C. S, Saliba, Kevin J, Leeper, Finian J
Published in MedChemComm (25.01.2023)
Published in MedChemComm (25.01.2023)
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Journal Article
Design of thiamine analogues for inhibition of thiamine diphosphate (ThDP)-dependent enzymes: Systematic investigation through Scaffold-Hopping and C2-Functionalisation
Chan, Alex H.Y., Ho, Terence C.S., Irfan, Rimsha, Hamid, Rawia A.A., Rudge, Emma S., Iqbal, Amjid, Turner, Alex, Hirsch, Anna K.H., Leeper, Finian J.
Published in Bioorganic chemistry (01.09.2023)
Published in Bioorganic chemistry (01.09.2023)
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Journal Article
Evaluation of ketoclomazone and its analogues as inhibitors of 1-deoxy-d-xylulose 5-phosphate synthases and other thiamine diphosphate (ThDP)-dependent enzymes
Chan, Alex H. Y., Ho, Terence C. S., Fathoni, Imam, Hamid, Rawia, Hirsch, Anna K. H., Saliba, Kevin J., Leeper, Finian J.
Published in MedChemComm (22.05.2024)
Published in MedChemComm (22.05.2024)
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Journal Article
Evaluation of ketoclomazone and its analogues as inhibitors of 1-deoxy--xylulose 5-phosphate synthases and other thiamine diphosphate (ThDP)-dependent enzymes
Chan, Alex H. Y, Ho, Terence C. S, Fathoni, Imam, Hamid, Rawia, Hirsch, Anna K. H, Saliba, Kevin J, Leeper, Finian J
Published in RSC medicinal chemistry (22.05.2024)
Published in RSC medicinal chemistry (22.05.2024)
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